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Synthesis of Heterocycles by Metathesis Reactions pp 33–55Cite as

The Synthesis of Cyclic Ether-Containing Natural and Non-natural Products by Metathesis Reactions

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Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 47))

Abstract

This chapter describes recent advances (2005–2015) in the use of metathesis reactions to construct the cyclic ether portions in the total synthesis of natural products. Advances in the synthesis of a range of marine polyether natural products are presented, and various strategic approaches to the bridged pyran-macrocycles neopeltolide and kendomycin are discussed. Finally, the synthesis of a range of biologically active, cyclic ether-based non-natural products is described.

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Authors and Affiliations

  1. Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow, G1 1XL, UK

    David M. Lindsay

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  1. David M. Lindsay
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Correspondence to David M. Lindsay .

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Editors and Affiliations

  1. School of Chemistry, University of Glasgow, Glasgow, United Kingdom

    Joëlle Prunet

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Lindsay, D.M. (2016). The Synthesis of Cyclic Ether-Containing Natural and Non-natural Products by Metathesis Reactions. In: Prunet, J. (eds) Synthesis of Heterocycles by Metathesis Reactions. Topics in Heterocyclic Chemistry, vol 47. Springer, Cham. https://doi.org/10.1007/7081_2015_197

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