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Metal-Free C–H Functionalization of Aromatic Compounds Through the Action of Nucleophilic Reagents

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Metal Free C-H Functionalization of Aromatics

Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 37))

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Abbreviations

Ar:

Aryl

Bu:

Butyl

DDQ:

2,3-Dichloro-5,6-dicyano-1,4-benzoquinone

DMF:

Dimethylformamide

DMSO:

Dimethyl sulfoxide

EEP:

Electron–electron–proton sequence

EPE:

Electron–proton–electron sequence

Et:

Ethyl

i-Pr:

Iso-propyl

Me:

Methyl

NMR:

Nuclear magnetic resonance

Nu:

Nucleophile

PEE:

Proton–electron–electron sequence

Ph:

Phenyl

SET:

Single electron transfer

SN H :

Nucleophilic aromatic substitution of hydrogen

SN H(AE):

Addition–elimination protocol for the SN H reactions

SN H(AO):

Addition–oxidation protocol for the SN H reactions

SN X :

Nucleophilic aromatic substitution of halogen X or other good leaving groups

t-Bu:

Tert-butyl

THF:

Tetrahydrofuran

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  1. I. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, S. Kovalevskaya/Akademicheskaya, 22/20, 620219, Ekaterinburg, Russian Federation

    Valery N. Charushin & Oleg N. Chupakhin

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  1. Valery N. Charushin
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  2. Oleg N. Chupakhin
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Correspondence to Valery N. Charushin .

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  1. Postovsky Institute of Organic Synthesis, Ural Federal University, Ekaterinburg, Russia

    Valery Charushin

  2. Postovsky Institute of Organic Synthesis, Ural Federal University, Ekaterinburg, Russia

    Oleg Chupakhin

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Charushin, V.N., Chupakhin, O.N. (2014). Metal-Free C–H Functionalization of Aromatic Compounds Through the Action of Nucleophilic Reagents. In: Charushin, V., Chupakhin, O. (eds) Metal Free C-H Functionalization of Aromatics. Topics in Heterocyclic Chemistry, vol 37. Springer, Cham. https://doi.org/10.1007/7081_2013_119

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