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Bioactive Phenothiazines and Benzo[a]phenothiazines: Spectroscopic Studies, and Biological and Biomedical Properties and Applications

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Bioactive Heterocycles VII

Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 16))

Abstract

Recent progress in spectroscopic, photophysical, photochemical and analytical studies, as well as in the biological and biomedical properties of bioactive phenothiazines and benzophenothiazines, is reviewed. Their electronic absorption and luminescence properties, and their complexation and interactions in organized media are discussed. Various applications, including analytical studies, relative to phenothiazines and benzophenothiazines are described. Among the important biological and biomedical properties of these compounds, their neurological effects, their antibacterial, antifungal, antiviral, antiparasitic and antitumour activities, and their cytotoxicity are particularly reviewed.

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Authors and Affiliations

  1. ITODYS, Université Paris 7 – Denis-Diderot, Associé au CNRS UMR 70-86, 1, rue Guy de la Brosse, 75005, Paris, France

    J. J. Aaron

  2. Laboratoire des Géomatériaux et Géologie de l'Ingénieur (G2I), Université Paris-Est Marne la Vallée, 5, boulevard Descartes, Champs-sur-Marne, 77454, Marne-la-Vallée Cedex 2, France

    J. J. Aaron

  3. Département de Chimie, Faculté des Sciences et Techniques, Université Cheikh Anta Diop, Dakar, Senegal

    M. D. Gaye Seye

  4. Department of Medical and Experimental Biochemistry, Medical Faculty, University Sv Kiril i Metodij, 50, Divija 6, 1000 Skopje, Macedonia

    S. Trajkovska

  5. Department of Medicinal Chemistry, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose-shi, 204-8588, Tokyo, Japan

    N. Motohashi

Authors
  1. J. J. Aaron
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  2. M. D. Gaye Seye
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  3. S. Trajkovska
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  4. N. Motohashi
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Correspondence to J. J. Aaron .

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Noboru Motohashi

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Aaron, J.J., Gaye Seye, M.D., Trajkovska, S., Motohashi, N. (2008). Bioactive Phenothiazines and Benzo[a]phenothiazines: Spectroscopic Studies, and Biological and Biomedical Properties and Applications. In: Motohashi, N. (eds) Bioactive Heterocycles VII. Topics in Heterocyclic Chemistry, vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7081_2008_125

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