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Bioactive Heterocycles II pp 173–222Cite as

Preparation, Structure, and Biological Properties of Phosphorus Heterocycles with a C – P Ring System

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Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 8))

Abstract

Phosphoric acid esters, phosphates, have three P–O bonds around the central P(V) atom in the molecule. Replacing a phosphate P–O bond by a P–C bond and reducing the number of oxygen atoms one by one, converts phosphates into phosphonates, phosphinates, and phosphine oxides. Phospha sugar is a pseudo-sugar whose hemiacetal ring of the sugar contains a phosphorus atom with a C–P–C bond in the heterocycle, and is not yet found in nature. Research on phosphorus heterocycles is not as popular as that on nitrogen heterocycles, nevertheless the research is quite challenging.

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Authors and Affiliations

  1. Biomedical Materials Laboratory, Nano Material Research Division, Department of Research, Graduate School of Science and Technology, Shizuoka University, Hamamatsu 432-8561, Japan

    Mitsuji Yamashita

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  1. Mitsuji Yamashita
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Correspondence to Mitsuji Yamashita .

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Shoji Eguchi

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Yamashita, M. (2007). Preparation, Structure, and Biological Properties of Phosphorus Heterocycles with a C – P Ring System. In: Eguchi, S. (eds) Bioactive Heterocycles II. Topics in Heterocyclic Chemistry, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7081_2007_086

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