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Chemistry of Biologically Active Isothiazoles

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Bioactive Heterocycles III

Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 9))

Abstract

The isothiazole ring as well as the corresponding benzo- and heterocondensed rings are present in many chemically interesting compounds. The isothiazole ring can be a substituent of a bioactive scaffold or the pharmacophore of bioactive molecules. New compounds have been designed, synthesised and tested towards different biological targets and, in many cases, they display interesting pharmaceutical activities. Different SAR studies are reported starting from already known isothiazole derivatives or from new compounds characterised by a particular substitution pattern aiming to improve the biological activity. Agrochemical applications are also reported.

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Authors and Affiliations

  1. Istituto di Chimica Organica “A. Marchesini”, Facoltà di Farmacia, Università di Milano, Via Venezian 21, 20133, Milano, Italy

    Francesca Clerici, Maria Luisa Gelmi, Sara Pellegrino & Donato Pocar

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  1. Francesca Clerici
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  2. Maria Luisa Gelmi
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  3. Sara Pellegrino
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  4. Donato Pocar
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Correspondence to Maria Luisa Gelmi .

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Mahmud Tareq Hassan Khan

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To our dear Prof Pocar for his retirement

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Clerici, F., Gelmi, M.L., Pellegrino, S., Pocar, D. (2007). Chemistry of Biologically Active Isothiazoles. In: Khan, M.T.H. (eds) Bioactive Heterocycles III. Topics in Heterocyclic Chemistry, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7081_2007_081

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