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Pertussis: Identification, Prevention and Control

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Pertussis Infection and Vaccines

Part of the book series: Advances in Experimental Medicine and Biology ((AMIDPH,volume 1183))

Abstract

Pertussis is a vaccine-preventable disease. Despite the high vaccination coverage among children, pertussis is considered a re-emerging disease for which identification, prevention and control strategies need to be improved. To control pertussis it is important to maintain a high vaccination coverage to protect the age groups considered at high risk for the disease. Laboratory confirmation of Bordetella pertussis infection together with a differential diagnostic test for other Bordetellae are prerequisite for a correct and timely diagnosis of pertussis. Moreover, investigations of antimicrobial susceptibility and whole genome sequencing may permit to monitor the circulation of antimicrobials resistant and/or vaccine-escape strains. Finally, the preventive framework should no longer consider pertussis exclusively as a childhood infectious disease, since adults may play a role in transmission events.

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  1. Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy

    Paola Stefanelli

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  1. Paola Stefanelli
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Correspondence to Paola Stefanelli .

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Editors and Affiliations

  1. Vaccine Preventable Diseases - Reference Labs Unit, Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy

    Giorgio Fedele

  2. Former Research Director in the Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy

    Clara Maria Ausiello

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Stefanelli, P. (2019). Pertussis: Identification, Prevention and Control. In: Fedele, G., Ausiello, C. (eds) Pertussis Infection and Vaccines. Advances in Experimental Medicine and Biology(), vol 1183. Springer, Cham. https://doi.org/10.1007/5584_2019_408

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