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Pro-Inflammatory Cytokines in Psychiatric Disorders in Children and Adolescents: A Review

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Advances in Experimental Medicine and Biology

Abstract

Cytokines are a large group of small proteins which play a significant role in cell signaling and regulate a variety of processes in organisms, including proliferation and differentiation of many cells, mediation in defense reactions and regulation of hematopoiesis. Cytokines can be divided into those with pro- and those with anti-inflammatory properties. In the group of pro-inflammatory cytokines the most important are: IL-1 beta, IL-6, TNF-alpha, and IFN-gamma. Pro-inflammatory cytokines might be involved in the pathophysiology of many psychiatric conditions in adults, but their role in children and adolescents is less clear. The aim of this article is to demonstrate the patterns of pro-inflammatory cytokines in children and adolescents.

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Conflicts of Interest

The authors declare no conflicts of interest in relation to this article.

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Authors and Affiliations

  1. Department of Child Psychiatry, Warsaw Medical University, 63A Zwirki i Wigury Street, 02-091, Warsaw, Poland

    Paulina Miłkowska & Tomasz Wolańczyk

  2. Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Warsaw Medical University, 63A Zwirki i Wigury Street, 02-091, Warsaw, Poland

    Katarzyna Popko & Urszula Demkow

Authors
  1. Paulina Miłkowska
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  2. Katarzyna Popko
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  3. Urszula Demkow
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  4. Tomasz Wolańczyk
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Correspondence to Paulina Miłkowska .

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Miłkowska, P., Popko, K., Demkow, U., Wolańczyk, T. (2017). Pro-Inflammatory Cytokines in Psychiatric Disorders in Children and Adolescents: A Review. In: Advances in Experimental Medicine and Biology(). Springer, Boston, MA. https://doi.org/10.1007/5584_2017_24

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  • DOI: https://doi.org/10.1007/5584_2017_24

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