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Tuberculosis of the Urogenital Tract in Adults in a Tertiary Referral Center

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Clinical Research Involving Pulmonary Disorders

Part of the book series: Advances in Experimental Medicine and Biology ((NR,volume 1040))

Abstract

The genitourinary system is the main location of extrapulmonary tuberculosis. In Poland, it occupies the third place after tuberculosis of the pleura and lymph nodes. The aim of this study was to evaluate the prevalence and characteristics of tuberculosis in the urogenital tract in adult patients in a tertiary referral center in the years 2007–2015. The retrospective study included 87 patients, 42 women and 45 men. The average age was 62 ± 15 years. Changes in the urinary tract were diagnosed in 91% of women and 64% of men. Testicular tuberculosis was found in ten men, prostate tuberculosis in five, and in individual cases tuberculosis of the epididymis, scrotum, uterus, and the fallopian tube were found. The diagnosis was confirmed by bacteriological methods in 47% of patients, by histopathological in 41%, and by molecular methods in 23% of patients. In 84% of patients urological or gynecological interventions had to be applied. Patients were burdened with a number of urological diseases or diseases affecting other systems which hampered the diagnosis of tuberculosis. Antituberculosis treatment gave good results. Urogenital tuberculosis is a multivariate disease and a standard unified approach is impossible.

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References

  • Ali A, Abdallah T (2012) Clinical presentation and epidemiology of female genital tuberculosis in eastern Sudan. Int J Gynaecol Obstet 8:236–238

    Article  Google Scholar 

  • Altiparmak MR, Trabulus S, Balkan II, Yalin SF, Denizli N, Aslan G, Doruk HE, Engin A, Tekin R, Birengel S, Cetin BD, Arslan F, Turhan V, Mert A (2015) Urinary tuberculosis: a cohort of 79 adult cases. Ren Fail 37:1157–1163

    Article  PubMed  Google Scholar 

  • Benchekroun A, Lachkar A, Soumana A, Farih M, Belahnech Z, Marzouk M, Faik M (1998) Urogenital tuberculosis. 80 cases. Ann Urol 32:89–94

    CAS  Google Scholar 

  • Błachnio M, Zielonka TM, Błachnio A, Jagodziński J (2014) Socio-economic status and the duration of pulmonary tuberculosis symptoms in women treated at the Mazovian Treatment Centre of Tuberculosis and Lung Diseases in Otwock. Pneumonol Alergol Pol 82(1):3–9.

    PubMed  Google Scholar 

  • CDC (2007) Reported tuberculosis incidence – United States, 2006. MMWR Wkly 56(11):245–250

    Google Scholar 

  • Chowdury AR, Dey RK (2013) Penile tuberculosis following intravesical Bacille Calmette-Guérin immunotherapy. Indian J Urol 29:64–66

    Article  Google Scholar 

  • de Daher EF, da Silva G, Barros E (2013) Renal tuberculosis in the modern era. Am J Trop Med Hyg 88:54–64

    Article  CAS  PubMed  Google Scholar 

  • Ellis E, Gallant V, Scholten D, Dawson K, Phypers M (2010). Tuberculosis in Canada 2009 – pre-release. 2010, Ottawa: Public Health Agency of Canada. http://www.phac-aspc.gc.ca/tbpc-latb/pubs/tbcan08pre/index-eng.ph. Accessed on 12 Oct 2016

  • Erkens CGM, Kalisvaart NA, Slump E, Sebek M, van Soolingen D (2007) Tuberculose in the Nederland 2005. Surveillancerapport. KNCV Tuberculosefonds, Den Haag

    Google Scholar 

  • Figueiredo AA, Lucon AM, Junior RF, Srougi M (2008) Epidemiology of urogenital tuberculosis worldwide. Int J Urol 15:827–832

    Article  PubMed  Google Scholar 

  • Forssbohm M, Zwahlen M, Loddenkemper R, Rieder HL (2008) Demographic characteristics of patients with extrapulmonary tuberculosis in Germany. Eur Respir J 31:99–105

    Article  CAS  PubMed  Google Scholar 

  • García-Rodríguez J, Álvarez-Díaz H, Lorenzo-García M, Mariño-Callejo A, Fernández-Rial Á, Sesma-Sánchez P (2011) Extrapulmonary tuberculosis: epidemiology and risk factors. Enferm Infec Microbiol Clin 29:502–509

    Article  Google Scholar 

  • Gupta NP, Kumar R, Mundada OP, Aron M, Hemal AK, Dogra PN, Seth A (2006) Reconstructive surgery for the management of genitourinary tuberculosis: a single center experience. J Urol 175:2150–2154

    Article  CAS  PubMed  Google Scholar 

  • Heydari AA, Movahhede Danesh MR, Ghazvini K (2014) Urine PCR evaluation to diagnose pulmonary tuberculosis. Jundishapur J Microbiol 7:e9311

    Article  PubMed  PubMed Central  Google Scholar 

  • Huang H, Li X, Jin J (2013) Epidemiology and clinical features of renal tuberculosis: 239 cases report. Beijing Da Xue Xue Bao 45:600–604

    PubMed  Google Scholar 

  • Jagodziński J, Zielonka TM, Błachnio M (2012) Socio-economic status and duration of TB symptoms in males treated at the Mazovian Treatment Centre of Tuberculosis and Lung Diseases in Otwock. Pneumonol Alergol Pol 80:533–540.

    PubMed  Google Scholar 

  • Kruijshar ME, Abubakar I (2009) Increase in extrapulmonary tuberculosis in England and Wales 1999–2006. Thorax 64:1090–1095

    Article  Google Scholar 

  • Kulchavenya E (2013) Best practice in the diagnosis and management of urogenital tuberculosis. Ther Adv Urol 5:143–151

    Article  PubMed  PubMed Central  Google Scholar 

  • Kulchavenya E (2014a) Extrapulmonary tuberculosis: are statistical reports accurate? Ther Adv Infect Dis 2:61–70

    PubMed  PubMed Central  Google Scholar 

  • Kulchavenya E (2014b) Urogenital tuberculosis: definition and classification. Ther Adv Infect Dis 2:117–122

    Google Scholar 

  • Kulchavenya E, Kholtobin D (2015) Diseases masking and delaying the diagnosis of urogenital tuberculosis. Ther Adv Urol 7:331–338

    Article  PubMed  PubMed Central  Google Scholar 

  • Lin J, Lai C, Chen Y, Lee S, Tsai S, Huang C, Chung HC, Liang SH, Lin HH (2009) Risk factors for extra-pulmonary tuberculosis compared to pulmonary tuberculosis. Int J Tuberc Lung Dis 13(5):620–625

    CAS  PubMed  Google Scholar 

  • Mahajan N, Naidu P, Deep Kaur S (2016) Insight into the diagnosis and management of subclinical genital tuberculosis in women with infertility. J Hum Reprod Sci 9:135–144

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mazza-Stalder J, Nicod L, Janssens J (2012) Extrapulmonary tuberculosis. Rev Mal Respir 29:566–578

    Article  CAS  PubMed  Google Scholar 

  • Merchant S, Bharati A, Merchant N (2013) Tuberculosis of the genitourinary system – urinary tract tuberculosis: renal tuberculosis. Part I. Indian J Radiol Imaging 23:46–63

    Article  PubMed  PubMed Central  Google Scholar 

  • Nakane K, Yasuda M, Deguchi T, Takahashi S, Tanaka K, Hayami H, Hamasuna R, Yamamoto S, Arakawa S, Matsumoto T (2014) Nationwide survey of urogenital tuberculosis in Japan. Int J Urol 21:1171–1177

    Article  PubMed  Google Scholar 

  • Portillo-Gomez L, Morris SL, Panduro A (2000) Rapid and efficient detection of extrapulmonary Mycobacterium tuberculosis by PCR analysis. Int J Tuberc Lung Dis 4:361–370

    CAS  PubMed  Google Scholar 

  • Rowinska-Zakrzewska E, Korzeniewska-Kosela M, Roszkowski-Sliz K (2013) Extrapulmonary tubrculosis in Poland 1974–2010. Pneumonol Alergol Pol 81:121–129.

    PubMed  Google Scholar 

  • Rowińska-Zakrzewska E, Korzeniewska-Koseła M, Roszkowski-Śliż K (2014) The epidemiological situation of tuberculosis in Poland: Part I. According to notification rates, the incidence of tuberculosis varies in different regions of Poland: is this true? Pneumonol Alergol Pol 82:342–348.

    PubMed  Google Scholar 

  • Rowińska-Zakrzewska E, Szopiński J, Remiszewski P, Szymańska D, Miller M, Pawlicka L, Zwolska-Kwiek Z (1995) Tuberculosis in the autopsy material: analysis of 1500 autopsies performed between 1972 and 1991 in the Institute of Tuberculosis and Chest Diseases, Warsaw, Poland. Tubercle Lung Dis 76:349–354

    Article  Google Scholar 

  • Shivakoti R, Sharma D, Mamoon G, Pham K (2017) Association of HIV infection with extrapulmonary tuberculosis: a systematic review. Infection 45(1):11–21

    Article  PubMed  Google Scholar 

  • Uno T, Numazaki S, Kato N, Egawa S (2014) Tuberculous epididymitis after Bacillus Calmette-Guérin intravesical therapy: a case report. Hinyokika Kiyo 60:291–294

    PubMed  Google Scholar 

  • WHO (2014) Global tuberculosis control: surveillance, planning, financing. WHO report 2014. World Health Organization, Geneva. ISBN:978 92 4 156480 9

    Google Scholar 

  • Zammarchi L, Bartalesi F, Bartoloni A (2014) Tuberculosis in tropical areas and immigrants. Mediterr J Hematol Infect Dis 6:e2014043

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Conflicts Interest

The authors declare no conflict of interest in relation to this article.

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Authors and Affiliations

  1. Mazovian Center for the Treatment of Lung Diseases and Tuberculosis in Otwock, Otwock, Poland

    Jacek Jagodziński

  2. Department of Family Medicine, Medical University of Warsaw, 1A Banacha Street, 02-097, Warsaw, Poland

    Tadeusz M. Zielonka & Katarzyna Życińska

  3. Department of Internal Medicine and Cardiology, Solec Hospital, Warsaw, Poland

    Krystyna Peplińska

Authors
  1. Jacek Jagodziński
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  2. Tadeusz M. Zielonka
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  3. Krystyna Peplińska
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  4. Katarzyna Życińska
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Corresponding author

Correspondence to Tadeusz M. Zielonka .

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Editors and Affiliations

  1. Opole Medical School, Opole, Poland

    Mieczyslaw Pokorski

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Jagodziński, J., Zielonka, T.M., Peplińska, K., Życińska, K. (2018). Tuberculosis of the Urogenital Tract in Adults in a Tertiary Referral Center. In: Pokorski, M. (eds) Clinical Research Involving Pulmonary Disorders. Advances in Experimental Medicine and Biology(), vol 1040. Springer, Cham. https://doi.org/10.1007/5584_2017_103

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