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Post Thrombotic Syndrome

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Thrombosis and Embolism: from Research to Clinical Practice

Part of the book series: Advances in Experimental Medicine and Biology ((AIM,volume 906))

Abstract

Venous insufficiency following deep venous thrombosis is known as the post thrombotic syndrome. Whilst its presentation and symptoms can vary slightly between individuals, it can have a profound effect on quality of life. Symptoms range from mild limb swelling to severe intractable ulceration. A number of scoring systems have been developed to help monitor the disease progression, response to treatment as well as to classify patients for research purposes.

Treatment involves a combination of therapies, including compression stockings, venous stenting for out flow obstruction and in some instances deep venous bypass. A considerable effort is made in preventing post thrombotic syndrome with a number of trials looking into the effect of prompt and stable anticoagulation, the effect of compression stockings, the effect of exercise and the outcomes following early thrombus removal strategies such as catheter directed and pharmacomechanical thrombolysis.

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Abbreviations

PTS:

post thrombotic syndrome

DVT:

deep vein thrombosis

CDT:

catheter directed thrombolysis

LMWH:

Low molecular weight heparin

VKA:

Vitamin K Antagonists

PMT:

Pharmaco-mechanical thrombolysis

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Authors and Affiliations

  1. Academic Section of Vascular Surgery, Charing Cross Hospital, Imperial College London, London, UK

    Andrew Busuttil, Chung Sim Lim & Alun H. Davies

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  1. Andrew Busuttil
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  2. Chung Sim Lim
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  3. Alun H. Davies
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Correspondence to Alun H. Davies .

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Editors and Affiliations

  1. Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden

    Md. Shahidul Islam

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© 2016 Springer International Publishing Switzerland

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Busuttil, A., Lim, C.S., Davies, A.H. (2016). Post Thrombotic Syndrome. In: Islam, M. (eds) Thrombosis and Embolism: from Research to Clinical Practice. Advances in Experimental Medicine and Biology(), vol 906. Springer, Cham. https://doi.org/10.1007/5584_2016_126

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  • DOI: https://doi.org/10.1007/5584_2016_126

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-22107-6

  • Online ISBN: 978-3-319-22108-3

  • eBook Packages: MedicineMedicine (R0)

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