Skip to main content
SpringerLink
Log in
Book cover

Neurotransmitter Interactions and Cognitive Function pp 35–39Cite as

Chemoresponsiveness and Breath Physiology in Anosmia

  • Chapter
  • First Online:

Part of the book series: Advances in Experimental Medicine and Biology ((NR,volume 837))

Abstract

Anosmia is a model to study the interaction among chemoreception systems. In the head injury, the traumatic irreversible anosmia caused by damage to olfactory nerve fibers and brain regions is of enviable research interest. In this study, psychophysiological tests for a comprehensive assessment of olfactory function were utilized to investigate anosmia, together with a new technique based on the breath real-time monitoring of volatile organic compounds (VOCs). We applied the breath and VOCs analysis to investigate chemoresponsiveness in the long-term irreversible post-traumatic anosmia.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Cain WS (1982) Sumner’s ‘On testing the sense of smell’ revisited. Yale J Biol Med 55:515–519

    CAS  PubMed Central  PubMed  Google Scholar 

  • Cain WS, Gent JP, Goodspeed RD, Leonard G (1988) Evaluation of olfactory dysfunction in the Connecticut Chemosensory Clinical Research Center. Laryngoscope 98:83–88

    Article  CAS  PubMed  Google Scholar 

  • Costanzo RM, Becker DP (1986) Smell and taste disorders in head injury and neurosurgery patients. In: Meiselman HL, Rivlin RS (eds) Clinical measurements of taste and smell. MacMillan Publishing Company, New York, pp 565–578

    Google Scholar 

  • Costanzo RM, Zasler ND (1991) Head trauma. In: Getchell TV, Doty RL, Bartoshuk LM, Snow JB Jr (eds) Smell and taste in health and disease. Raven, New York, pp 711–730

    Google Scholar 

  • Doty RL, Shaman P, Dunn M (1984) Development of the University of Pennsylvania Smell Identification Test: a standardized microencapsulated test of olfactory function. Physiol Behav 32:489–502

    Article  CAS  PubMed  Google Scholar 

  • Doty RL, Yousem DM, Pham LT, Kreshak AA, Geckle R, Lee WW (1997) Olfactory dysfunction in patients with head trauma. Arch Neurol 54:1131–1145

    Article  CAS  PubMed  Google Scholar 

  • Hummel T, Sekinger B, Wolf SR, Pauli E, Kobal G (1997) Sniffin’ sticks: olfactory performance assessed by the combined testing of odor identification, odor discrimination and odor threshold. Chem Senses 22:39–52

    Article  CAS  PubMed  Google Scholar 

  • Mazzatenta A, Di Giulio C, Pokorski M (2013a) Pathologies currently identified by exhaled biomarkers. Respir Physiol Neurobiol 187:128–134

    Article  CAS  PubMed  Google Scholar 

  • Mazzatenta A, Pokorski M, Cozzutto S, Barbieri P, Veratti V, Di Giulio C (2013b) Non-invasive assessment of exhaled breath pattern in patients with multiple chemical sensibility disorder. Adv Exp Med Biol 756:179–188

    Article  CAS  PubMed  Google Scholar 

  • Mazzatenta A, Pokorski M, Di Giulio C (2013c) Real time breath analysis in type 2 diabetes mellitus patients during cognitive task. Adv Exp Med Biol 788:247–253

    Article  PubMed  Google Scholar 

  • Mueller CA, Hummel T (2009) Recovery of olfactory function after nine years of post-traumatic anosmia: a case report. J Med Case Rep 1–3:9283

    Article  Google Scholar 

  • Reden J, Mueller A, Mueller C, Konstantinidis I, Frasnelli J, Landis BN, Hummel T (2006) Recovery of olfactory function following closed head injury or infections of the upper respiratory tract. Arch Otolaryngol Head Neck Surg 132:265–269

    Article  PubMed  Google Scholar 

  • Sumner D (1975) Disturbance of the senses of smell and taste after head injuries. In: Vinken PH, Bruyn GW (eds) Handbook of clinical neurology. North-Holland Publishing Company, Amsterdam, pp 1–25

    Google Scholar 

  • Sumner D (1964) Post-traumatic anosmia. Brain 87:107–129

    Article  CAS  PubMed  Google Scholar 

  • Temmel AF, Quint C, Schickinger-Fischer B, Klimek L, Stoller E, Hummel T (2002) Characteristics of olfactory disorders in relation to major causes of olfactory loss. Arch Otolaryngol Head Neck Surg 128:635–641

    Article  PubMed  Google Scholar 

  • Zusho H (1982) Posttraumatic anosmia. Arch Otolaryngol 108:90–92

    Article  CAS  PubMed  Google Scholar 

Download references

Conflicts of Interest

The authors declare no conflicts of interest in relation to this article.

Author information

Authors and Affiliations

  1. Sensorial Physiology Unit, Department of Neuroscience and Imaging, “G. d’Annunzio” University of Chieti–Pescara, 66013, Chieti, Italy

    Andrea Mazzatenta, Danilo Montinaro & Camillo Di Giulio

  2. Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy

    Andrea Mazzatenta

  3. Neuroscience Institute, C.N.R., Pisa, Italy

    Andrea Mazzatenta

  4. Department of Nursing, Public Higher Medical Professional School in Opole, 68 Katowicka St., 45-060, Opole, Poland

    Mieczyslaw Pokorski

  5. Institute of Psychology, University of Opole, Opole, Poland

    Mieczyslaw Pokorski

  6. Department of Psychiatry and Psychology, ASL 2, Chieti, Italy

    Danilo Montinaro

Authors
  1. Andrea Mazzatenta
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mieczyslaw Pokorski
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Danilo Montinaro
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Camillo Di Giulio
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Andrea Mazzatenta .

Editor information

Editors and Affiliations

  1. Institute of Psychology, Opole University, Poland

    Mieczyslaw Pokorski

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Mazzatenta, A., Pokorski, M., Montinaro, D., Di Giulio, C. (2014). Chemoresponsiveness and Breath Physiology in Anosmia. In: Pokorski, M. (eds) Neurotransmitter Interactions and Cognitive Function. Advances in Experimental Medicine and Biology(), vol 837. Springer, Cham. https://doi.org/10.1007/5584_2014_66

Download citation

Publish with us

Policies and ethics

Search

Navigation