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Metabolomics pp 235–252Cite as

The exo-metabolome in filamentous fungi

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Part of the book series: Topics in Current Genetics ((TCG,volume 18))

Abstract

Filamentous fungi are a diverse group of eukaryotic microorganisms that have a significant impacton human life as spoilers of food and feed by degradation and toxin production. They are also mostuseful as a source of bulk and fine chemicals and pharmaceuticals. This chapter focuses on the exo-metabolomein filamentous fungi, which comprises more than 30,000 known secondary metabolites. Profiles of thisdiverse range of secondary metabolites have, for more than 25 years, been central in development offungal systematics, taxonomy, and ecology, today integrated in a multidisciplinary and polyphasicapproach to applied mycology. Lead discovery is an example of the successful integration of metaboliteprofiling and natural product chemistry in mycology.

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Authors and Affiliations

  1. Center for Microbial Biotechnology, BioCentrum-DTU, Technical University of Denmark, Søltofts Plads 221, DK-2800, Kgs. Lyngby, Denmark

    Ulf Thrane, Birgitte Anderson, Jens C. Frisvad & Jørn Smedsgaard

Authors
  1. Ulf Thrane
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  2. Birgitte Anderson
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  3. Jens C. Frisvad
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  4. Jørn Smedsgaard
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Corresponding author

Correspondence to Ulf Thrane .

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Jens Nielsen Michael C. Jewett

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© 2007 Springer-Verlag Berlin Heidelberg

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Thrane, U., Anderson, B., Frisvad, J.C., Smedsgaard, J. (2007). The exo-metabolome in filamentous fungi. In: Nielsen, J., Jewett, M.C. (eds) Metabolomics. Topics in Current Genetics, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/4735_2007_0230

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