Fluorescence in Pharmaceutics and Cosmetics

  • Maurício da Silva BaptistaEmail author
  • Erick Leite BastosEmail author
Part of the Springer Series on Fluorescence book series (SS FLUOR, volume 18)


Fluorescence is a visually appealing phenomenon that revolutionized many fields of science and technology. The abilities to see biological processes as they occur, monitor drug delivery and action, stain specific cells, and highlight microscopic structures are some of the applications of fluorescence that are changing our daily lives. This chapter discusses the use of the fluorescence phenomenon in pharmaceuticals and cosmetics focusing on the toxicology and the use of task-specific fluorescent materials and development of sensitive and selective analytical and imaging methods. Noninvasive bioimaging using endogenous fluorophores as probes, emerging techniques related to fluorescence, and a brief description of selected fundamental concepts in photoscience are provided for completeness.


Cosmetics Drug discovery Dyes Fluorescence Hair Labels Microscopy Nanomaterials Pharmaceuticals Photoprotection Probes Skin 



Molar absorption coefficient


Absorption wavelength


Emission wavelength


Excitation wavelength


Lifetime of the singlet excited state


Fluorescence quantum yield


Aequorea-derived fluorescent proteins


Active pharmaceutical ingredients


Carbon nanodots


Carbon nanotubes


Charge transfer


Fluorescent dye-doped silica nanoparticles


Fluorescence cross-correlation spectroscopy


Fluorescence correlation spectroscopy


Fluorescence lifetime measurements


Fluorescent protein


Fluorescence photobleaching recovery


Förster resonance energy transfer


Green fluorescent protein




Graphene oxide


Molecular beacons


New chemical entities




Near infrared


Photoinduced electron transfer

Ph. Eur.

European Pharmacopoeia


Semiconductor quantum dots


Solution-phase single-pair FRET


Time-resolved fluorescence


Lanthanide-based upconversion nanoparticles


US Pharmacopeia



We thank the São Paulo Research Foundation (FAPESP), the Brazilian National Council for Scientific and Technological Development (CNPq), the Coordination for the Improvement of Higher Education Personnel (CAPES), and Natura Cosmetics for the financial support.

Conflict of Interest Statement

The authors declare that there are no conflicts of interest associated with this publication.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Instituto de Química, Universidade de São PauloSão PauloBrazil

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