Abstract
The unique properties of lanthanides as analytical luminophores may only be efficiently exploited when the measuring instrument has been especially designed for this particular purpose. Nowadays, many commercial plate fluorometers can be equipped for time-resolved measurements. However, not all of them perform to the limits of the luminophores: time-gating alone does not constitute an optimally sensitive measuring device but other factors such as the performance of optical components need also to be considered. The scope of this chapter is to underline these special, practical design requirements and solutions rather than give generic outlines on how fluorometers need to be built.
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Wieder I (1982) Luminescent antibody composition for immunofluorometric assay. US Patent 4,341,957
Soini E, Hemmilä I (1983) Luminescence spectroscopy assay means with luminescent chelate of europium. US Patent 4,374,120A
Diamandis EP (1999) Europium and terbium chelators for time-resolved fluorometric assay. EP0635006B1
Meurman OH, Hemmilä IA, Lövgren TN-E et al (1982) Time-resolved fluoroimmunoassay: a new test for rubella antibodies. J Clin Microbiol 16:920–925
Hamamatsu (2005) Technical information, xenon flash lamps. http://sales.hamamatsu.com/assets/applications/ETD/Xe-F_TLSX9001E05.pdf. Accessed 14 June 2009
Jury P (2007) Microchip lasers: beyond the visible. Laser Focus World, 1 April 2007
Laser diodes stretch further into the UV. Optics.org News. http://optics.org/article/37228. Accessed 22 March 2011
Eom IY (2005) Application of light emitting diodes as solid state light sources in analytical chemistry. Doctoral Dissertation, Texas Tech University
Hamamatsu (2005) Photon counting. Using photomultiplier tubes. http://sales.hamamatsu.com/assets/applications/ETD/PhotonCounting_TPHO9001E04.pdf. Accessed 14 June 2009
Sun X, Krainak M, Gentry B (2007) New developments in detector technology at wavelengths >1 micron. http://space.hsv.usra.edu/LWG/Jul07/Papers.jul07/Sun.jul07.pdf. Accessed 14 June 2007
Image Sensors World (2010) Hamamatsu develops MEMS-based photomultiplier tube technology. http://image-sensors-world.blogspot.com/2010/10/hamamatsu-develops-mems-based.html. Accessed 22 March 2011
Buzhana P, Dolgoshein B, Ilyin A et al (2001) ICFA instrumentation bulletin. http://www.slac.stanford.edu/pubs/icfa/fall01/paper3/paper3.pdf. Accessed 24 June 2009
Golovina V, Savelievb V (2004) Novel type of avalanche photodetector with Geiger mode operation. Nucl Instrum Meth Phys Res A 518:560–564
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Kuusisto, A., Hänninen, P. (2011). Time-Domain Measurements. In: Hänninen, P., Härmä, H. (eds) Lanthanide Luminescence. Springer Series on Fluorescence, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/4243_2011_18
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DOI: https://doi.org/10.1007/4243_2011_18
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