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Regulation of Excitability by Potassium Channels

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Inhibitory Regulation of Excitatory Neurotransmission

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 44))

Abstract

Neurons express a large number of different voltage-gated potassium (Kv) channels with distinct biophysical and biochemical properties. Possibly, this diversity reflects the need to regulate and fine-tune neuronal excitability at various levels of complexity in space and time. In this context, Kv channels operating in the subthreshold range of action- potential firing are of particular interest. It is likely that these Kv channels play a prominent role in both propagating and integrating dendritic signaling, as well as axonal action-potential firing and propagation.

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Authors and Affiliations

  1. Institute for Neural Signal Conduction, Center for Molecular Neurobiology, University Hospital Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany

    O. Pongs

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  1. O. Pongs
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Correspondence to O. Pongs .

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Mark G. Darlison

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© 2007 Springer-Verlag Berlin Heidelberg

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Pongs, O. (2007). Regulation of Excitability by Potassium Channels. In: Darlison, M.G. (eds) Inhibitory Regulation of Excitatory Neurotransmission. Results and Problems in Cell Differentiation, vol 44. Springer, Berlin, Heidelberg. https://doi.org/10.1007/400_2007_032

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