Summary
“Barreloids” and “barrels” are patch-like structure representing single whiskers observed in the ventroposterior thalamic nucleus (VP) and somatosensory cortex in rodents, respectively. They are characteristic structure observed during the early neonatal period, which is an important period for the development of the networks in VP and somatosensory cortex. Various neurotransmitter systems have been reported to be involved in the development of these structure including, serotonergic, glutamatargic, GABAergic and cholinergic ones. The present study indicated that immunoreactivity for a calcium binding protein, S-100B, was transiently found as “barreloids” in VP at postnatal day (PND) 7 and as “barrels” in the somatosensory layer IV at PND 15, respectively. “Barrel” - like 5-hydroxytriptamine transporter (5-HTT) immunoreactivity was also found in the somatosensory cortex at PND 15. Morphological findings indicated that S-100B was present in cellular nuclei and released into extracellular space in both the thalamus and cortex. S-100B is suggested to be involved in the formation or remodeling of networks in VP and the somatosensory cortex via modulating calcium levels intra- and extracellularly beside changes in related neurotransmitters.
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© 2006 Springer-Verlag Tokyo
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Muneoka, K.T., Funahashi, H., Ogawa, T., Kuwagata, M., Whitaker-Azmitia, P.M., Shioda, S. (2006). S-100B Expression in Neonatal Rat Cortical “Barrels” and Thalamic “Barreloids”. In: Homma, I., Shioda, S. (eds) Breathing, Feeding, and Neuroprotection. Springer, Tokyo. https://doi.org/10.1007/4-431-28775-2_13
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DOI: https://doi.org/10.1007/4-431-28775-2_13
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-28774-2
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