Abstract
Up to 20 years ago, it was generally believed that undifferentiated multipotent cells do not exist in adult mammals. But recent studies have revealed that stem cells, which are capable of broad differentiation and self-renewal, exist in various tissues in young and adult mammalian animals. Moreover, these somatic stem cells reportedly possess a differentiation potential to change into functional cells of other organs. Non-neural tissues such as dermis, adipose tissue and bone marrow are thus expected to offer sources of cells for regenerative treatment of severe neurological disorders, including spinal cord injury, traumatic brain injury, Parkinson’s disease and stroke.
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© 2006 Springer-Verlag Tokyo
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Magaki, T., Kurisu, K., Okazaki, T. (2006). Ex vivo Expansion and Neural Differentiation of Bone Marrow-derived Cells under Serum-free Condition. In: Kanno, T., Kato, Y. (eds) Minimally Invasive Neurosurgery and Multidisciplinary Neurotraumatology. Springer, Tokyo. https://doi.org/10.1007/4-431-28576-8_40
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DOI: https://doi.org/10.1007/4-431-28576-8_40
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-28551-9
Online ISBN: 978-4-431-28576-2
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