4. Conclusion
The focused analysis for the metabolites obtained by rough separation with the differences in solubility compared to the extraction solvent is very effective, because further separation such as by LC or CE conditions suitable for the chemical properties of these metabolites is more easily selected. This is true for all metabolomics studies, especially in the detection of minor components. By using the differences in solubility, metabolites can be categorized into different groups of chemical and physiological nature. For each specified category of the metabolites, specified fields of metabolomics such as for peptidome, glycome, and lipidome can exist. It is very important that new strategies of analytical methods and databases for each of these categories of metabolites are created.
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Taguchi, R. (2005). Application of Electrospray Ionization Mass Spectrometry for Metabolomics. In: Tomita, M., Nishioka, T. (eds) Metabolomics. Springer, Tokyo. https://doi.org/10.1007/4-431-28055-3_3
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DOI: https://doi.org/10.1007/4-431-28055-3_3
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