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Iridium-Catalyzed Asymmetric Hydrogenation

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Iridium Catalysts for Organic Reactions

Part of the book series: Topics in Organometallic Chemistry ((TOPORGAN,volume 69))

Abstract

In this chapter, we describe the development in homogeneous Ir-catalyzed asymmetric hydrogenation with particular emphasis on the achievements made during the last 10 years. We also present their application to the synthesis of complex molecules. The first section deals with the hydrogenation of unfunctionalized olefins or with poorly coordinative groups. The second section includes the advances made in the hydrogenation of functionalized olefins. The last two sections cover the hydrogenation of imines and ketones, respectively.

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Acknowledgments

We gratefully acknowledge financial support from the Spanish Ministry of Economy and Competitiveness (CTQ2016-74878-P and PID2019-104904GB-I00), the European Regional Development Fund (AEI/FEDER, UE), the Catalan Government (2017SGR1472), the ICREA Foundation (ICREA Academia award to MD) and from “La Caixa” Foundation.

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  1. Departament de Química Física i Inorgànica, Universitat Rovira i Virgili, Tarragona, Spain

    Jèssica Margalef, Oscar Pàmies & Montserrat Diéguez

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  1. Jèssica Margalef
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  2. Oscar Pàmies
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  3. Montserrat Diéguez
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Correspondence to Montserrat Diéguez .

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  1. Department of Inorganic Chemistry, University of Zaragoza-CSIC, Zaragoza, Spain

    Luis A. Oro

  2. Department of Physical and Inorganic Chemistry, University Rovira i Virgili, Tarragona, Spain

    Carmen Claver

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Margalef, J., Pàmies, O., Diéguez, M. (2020). Iridium-Catalyzed Asymmetric Hydrogenation. In: Oro, L.A., Claver, C. (eds) Iridium Catalysts for Organic Reactions. Topics in Organometallic Chemistry, vol 69. Springer, Cham. https://doi.org/10.1007/3418_2020_64

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