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Iridium-Catalyzed Undirected Homogeneous C–H Borylation Reaction

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Book cover Iridium Catalysts for Organic Reactions

Part of the book series: Topics in Organometallic Chemistry ((TOPORGAN,volume 69))

Abstract

The present chapter describes the intense efforts devoted to develop new concepts from 2014 up today in the iridium-catalyzed undirected homogeneous C–H borylation of heteroarenes, arenes, and alkanes. Selectivity issues are principally highlighted in this chapter since no directed groups are included in these approaches, but improved ligands are responsible of the new trends instead. In parallel, mechanistic insights on the C–B bond formation analyzed through density functional theory orientate the suggestion of alternative catalytic cycles, to understand the high level of selectivity on Csp2-H and Csp3-H borylation. This area of work keeps very active because of the inherent interest on the C–B bond formation allowing access to multifunctionalized products, in a straightforward manner.

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Author information

Authors and Affiliations

  1. Dept. Química Física i Inorgànica, Faculty of Chemistry, Tarragona, Spain

    Elena Fernández

Authors
  1. Elena Fernández
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Correspondence to Elena Fernández .

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Editors and Affiliations

  1. Department of Inorganic Chemistry, University of Zaragoza-CSIC, Zaragoza, Spain

    Luis A. Oro

  2. Department of Physical and Inorganic Chemistry, University Rovira i Virgili, Tarragona, Spain

    Carmen Claver

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Fernández, E. (2020). Iridium-Catalyzed Undirected Homogeneous C–H Borylation Reaction. In: Oro, L.A., Claver, C. (eds) Iridium Catalysts for Organic Reactions. Topics in Organometallic Chemistry, vol 69. Springer, Cham. https://doi.org/10.1007/3418_2020_53

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