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Nanoparticle Catalysts in Flow Systems

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Nanoparticles in Catalysis

Part of the book series: Topics in Organometallic Chemistry ((TOPORGAN,volume 66))

Abstract

By taking advantage of the high catalytic activity and high turnover frequency (TOF) of heterogeneous metal nanoparticle catalysts, continuous-flow systems, in which introduced reactants are converted into the desired product in high yield, can be realized. These continuous-flow reactors possess high compatibility with sequential continuous-flow systems, which enable multistep flow synthesis of biologically active compounds such as active pharmaceutical ingredients (APIs) and natural products.

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References

  1. Kobayashi S (2016) Chem Asian J 11:425–436

    Article  CAS  PubMed  Google Scholar 

  2. Kobayashi S, Miyamura H (2013) Aldrichimica Acta 46:3–19

    CAS  Google Scholar 

  3. Kobayashi J, Mori Y, Okamoto K, Akiyama R, Ueno M, Kitamori T, Kobayashi S (2004) Science 304:1305–1308

    Article  CAS  PubMed  Google Scholar 

  4. Oyamada H, Akiyama R, Hagio H, Naito T, Kobayashi S (2006) Chem Commun:4297–4299

    Google Scholar 

  5. Ueno M, Suzuki T, Naito T, Oyamada H, Kobayashi S (2008) Chem Commun:1647–1649

    Google Scholar 

  6. Miyamura H, Matsubara R, Miyazaki Y, Kobayashi S (2007) Angew Chem Int Ed 46:4151–4154

    Article  CAS  Google Scholar 

  7. Wang N, Matsumoto T, Ueno M, Miyamura H, Kobayashi S (2009) Angew Chem Int Ed 48:4744–4746

    Article  CAS  Google Scholar 

  8. Kenis PJA, Ismagilov RF, Whitesides GM (1999) Science 285:83

    Article  CAS  PubMed  Google Scholar 

  9. Uozumi Y, Yamada YMA, Beppu T, Fukuyama N, Ueno M, Kitamori T (2006) J Am Chem Soc 128:15994–15995

    Article  CAS  PubMed  Google Scholar 

  10. Yamada YM, Watanabe T, Ohno A, Uozumi Y (2012) ChemSusChem 5:293–299

    Article  CAS  PubMed  Google Scholar 

  11. Oyamada H, Naito T, Miyamoto S, Akiyama R, Hagio H, Kobayashi S (2008) Org Biomol Chem 6:61–65

    Article  CAS  PubMed  Google Scholar 

  12. Oyamada H, Naito T, Kobayashi S (2011) Beilstein J Org Chem 7:735–739

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Kobayashi S, Okumura M, Akatsuka Y, Miyamura H, Ueno M, Oyamada H (2015) ChemCatChem 7:4025–4029

    Article  CAS  Google Scholar 

  14. Saito Y, Ishitani H, Kobayashi S (2016) Asian J Org Chem 5:1124–1127

    Article  CAS  Google Scholar 

  15. Ishitani H, Saito Y, Tsubogo T, Kobayashi S (2016) Org Lett 18:1346–1349

    Article  CAS  PubMed  Google Scholar 

  16. Saito Y, Ishitani H, Ueno M, Kobayashi S (2017) ChemistryOpen 6:211–215

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Tsubogo T, Oyamada H, Kobayashi S (2015) Nature 520:329–332

    Article  CAS  PubMed  Google Scholar 

  18. Saaby S, Knudsen KR, Ladlow M, Ley SV (2005) Chem Commun:2909–2911

    Google Scholar 

  19. Laroche B, Ishitani H, Kobayashi S (2018) Adv Synth Catal 360:4699–4704

    Article  CAS  Google Scholar 

  20. Irfan M, Petricci E, Glasnov TN, Taddei M, Kappe CO (2009) Eur J Org Chem 2009:1327–1334

    Article  Google Scholar 

  21. Ouchi T, Battilocchio C, Hawkins JM, Ley SV (2014) Org Process Res Dev 18:1560–1566

    Article  CAS  Google Scholar 

  22. Miyamura H, Suzuki A, Yasukawa T, Kobayashi S (2018) J Am Chem Soc 140:11325–11334

    Article  CAS  PubMed  Google Scholar 

  23. Zotova N, Hellgardt K, Kelsall GH, Jessiman AS, Hii KK (2010) Green Chem 12:2157

    Article  CAS  Google Scholar 

  24. Kaizuka K, Miyamura H, Kobayashi S (2010) J Am Chem Soc 132:15096–15098

    Article  CAS  PubMed  Google Scholar 

  25. Kaizuka K, Lee K-Y, Miyamura H, Kobayashi S (2012) J Flow Chem 2:1

    Article  CAS  Google Scholar 

  26. Mannel DS, Ahmed MS, Root TW, Stahl SS (2017) J Am Chem Soc 139:1690–1698

    Article  CAS  PubMed  Google Scholar 

  27. Gross E, Liu Jack H-C, Toste FD, Somorjai GA (2012) Nat Chem 4:947–952

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Shū Kobayashi .

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Miyamura, H., Kobayashi, S. (2020). Nanoparticle Catalysts in Flow Systems. In: Kobayashi, S. (eds) Nanoparticles in Catalysis. Topics in Organometallic Chemistry, vol 66. Springer, Cham. https://doi.org/10.1007/3418_2020_46

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