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Application of Organometallic Catalysts in API Synthesis

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Organometallics in Process Chemistry

Part of the book series: Topics in Organometallic Chemistry ((TOPORGAN,volume 65))

Abstract

Inherent creativity in synthetic organic chemists is hallucinogenic and found to have potential to impact global healthcare industry incredibly by executing contemporary organometallic strategies to manufacture the products of varied interest. Application of organometallics in chemical industry has intensely perfected the manufacturing of the materials right from trade goods to very personalized medicines without generating significant amount of waste. In pursuit of drug development, two types of challenges are encountered. The first one is related to design of the molecules, and the second is related to the manufacturing of these at commercial scale. Contemporary organometallics in the context of drug development and process research have advanced the toolbox of enabling technologies for addressing these challenges posed during drug development.

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Authors and Affiliations

  1. Integrated Product Development, Innovation Plaza, Dr. Reddy’s Laboratories Ltd, Qutubullapur, Telangana, India

    Debjit Basu, Srinivas Achanta, N. Uday Kumar, Rajeev Bhudhdev Rehani & Rakeshwar Bandichhor

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  4. Rajeev Bhudhdev Rehani
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  5. Rakeshwar Bandichhor
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Correspondence to Rakeshwar Bandichhor .

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  1. MilliporeSigma (A business of Merck KGaA, Darmstadt, Germany), Milwaukee, WI, USA

    Thomas J. Colacot

  2. Johnson Matthey, Taloja, Maharashtra, India

    Vilvanathan Sivakumar

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Basu, D., Achanta, S., Kumar, N.U., Rehani, R.B., Bandichhor, R. (2019). Application of Organometallic Catalysts in API Synthesis. In: Colacot, T., Sivakumar, V. (eds) Organometallics in Process Chemistry. Topics in Organometallic Chemistry, vol 65. Springer, Cham. https://doi.org/10.1007/3418_2019_31

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