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Artificial Metalloproteins Exploiting Vacant Space: Preparation, Structures, and Functions

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Topics in Organometallic Chemistry

Part of the book series: Topics in Organometallic Chemistry

Abstract

Molecular design of artificial metalloproteins is one of the most attractive subjects in bioinorganic chemistry. Protein vacant space has been utilized to prepare artificial metalloproteins because it provides a unique chemical environment for application to catalysts and to biomaterials bearing electronic, magnetic, and medical properties. Recently, X-ray crystal structural analysis has increased in this research area because it is a powerful tool for understanding the interactions of metal complexes and protein scaffolds, and for providing rational design of these composites. This chapter reviews the recent studies on the preparation methods and X-ray crystal structural analyses of metal/protein composites, and their functions as catalysts, metal-drugs, etc.

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Authors and Affiliations

  1. Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan

    Satoshi Abe

  2. PRESTO, Japan Science and Technology Agency (JST), Saitama, 332-0012, Japan

    Takafumi Ueno

  3. Research Center for Materials Science, Nagoya University, Nagoya 464-8602, Japan

    Yoshihito Wantanable

  4. Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto 615-8510, Japan

    Satoshi Abe & Takafumi Ueno

Authors
  1. Satoshi Abe
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  2. Takafumi Ueno
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  3. Yoshihito Wantanable
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Correspondence to Yoshihito Wantanable .

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© 2008 Springer-Verlag London

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Abe, S., Ueno, T., Wantanable, Y. (2008). Artificial Metalloproteins Exploiting Vacant Space: Preparation, Structures, and Functions. In: Topics in Organometallic Chemistry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3418_2008_4

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  • DOI: https://doi.org/10.1007/3418_2008_4

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