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Complement and Kidney Disease pp 65–83Cite as

Non-Shiga toxin-associated hemolytic uremic syndrome

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References

  1. Ruggenenti P, Noris M, Remuzzi G (2001) Thrombotic microangiopathy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Kidney Int 60: 831–846

    CAS  PubMed  Google Scholar 

  2. Thorpe CM (2004) Shiga toxin-producing Escherichia coli infection. Clin Infect Dis 38: 1298–1303

    Article  PubMed  Google Scholar 

  3. Karmali MA, Steele BT, Petric M, Lim C (1983) Sporadic cases of haemolytic-uraemic syndrome associated with faecal cytotoxin and cytotoxin-producing Escherichia coli in stools. Lancet 1: 619–620

    CAS  PubMed  Google Scholar 

  4. Riley LW, Remis RS, Helgerson SD, McGee HB, Wells JG, Davis BR, Hebert RJ, Olcott ES, Johnson LM, Hargrett NT, Blake PA, Cohen ML (1983) Hemorrhagic colitis associated with a rare Escherichia coli serotype. N Engl J Med 308: 681–685

    CAS  PubMed  Google Scholar 

  5. Mead PS, Griffin PM (1998) Escherichia coli O157:H7. Lancet 352: 1207–1212

    Article  CAS  PubMed  Google Scholar 

  6. Jackson MP, Newland JW, Holmes RK, O’Brien AD (1987) Nucleotide sequence analysis of the structural genes for Shiga-like toxin I encoded by bacteriophage 933J from Escherichia coli. Microb Pathog 2: 147–153

    CAS  PubMed  Google Scholar 

  7. Gianviti A, Rosmini F, Caprioli A, Corona R, Matteucci MC, Principato F, Luzzi I, Rizzoni G (1994) Haemolytic-uraemic syndrome in childhood: surveillance and case-control studies in Italy. Italian HUS Study Group. Pediatr Nephrol 8: 705–709

    CAS  PubMed  Google Scholar 

  8. Kaplan BS, Meyers KE, Schulman SL (1998) The pathogenesis and treatment of hemolytic uremic syndrome. J Am Soc Nephrol 9: 1126–1133

    CAS  PubMed  Google Scholar 

  9. Tonshoff B, Sammet A, Sanden I, Mehls O, Waldherr R, Scharer K (1994) Outcome and prognostic determinants in the hemolytic uremic syndrome of children. Nephron 68: 63–70

    CAS  PubMed  Google Scholar 

  10. Banatvala N, Griffin PM, Greene KD, Barrett TJ, Bibb WF, Green JH, Wells JG (2001) The United States National Prospective Hemolytic Uremic Syndrome Study: microbiologic, serologic, clinical, and epidemiologic findings. J Infect Dis 183: 1063–1070

    Article  CAS  PubMed  Google Scholar 

  11. Milford D (1992) The hemolytic uremic syndromes in the United Kingdom. In: BSTR Kaplan, JL Moake (eds): Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura. Marcel Dekker Inc., New York, 39–59

    Google Scholar 

  12. Van Dyck M, Proesmans W, Depraetere M (1988) Hemolytic uremic syndrome in childhood: renal function ten years later. Clin Nephrol 29: 109–112

    PubMed  Google Scholar 

  13. Schieppati A, Ruggenenti P, Cornejo RP, Ferrario F, Gregorini G, Zucchelli P, Rossi E, Remuzzi G (1992) Renal function at hospital admission as a prognostic factor in adult hemolytic uremic syndrome. The Italian Registry of Haemolytic Uremic Syndrome. J Am Soc Nephrol 2: 1640–1644

    CAS  PubMed  Google Scholar 

  14. Taylor CM, Chua C, Howie AJ, Risdon RA (2004) Clinico-pathological findings in diarrhoea-negative haemolytic uraemic syndrome. Pediatr Nephrol 19: 419–425

    CAS  PubMed  Google Scholar 

  15. Constantinescu AR, Bitzan M, Weiss LS, Christen E, Kaplan BS, Cnaan A, Trachtman H (2004) Non-enteropathic hemolytic uremic syndrome: causes and short-term course. Am J Kidney Dis 43: 976–982

    PubMed  Google Scholar 

  16. Taylor CM, Howie AJ, Williams JM (1999) No common final pathogenetic pathway in haemolytic uraemic syndromes. Nephrol Dial Transplant 14: 1100–1102

    CAS  PubMed  Google Scholar 

  17. Remuzzi G, Ruggenenti P (1994) Thrombotic microangiopathies. In: C Tisher, B Brenner (eds): Renal Pathology, 2nd ed. J.B. Lippincott, Philadelphia, 1154–1184

    Google Scholar 

  18. Kincaid-Smith P (1975) Participation of intravascular coagulation in the pathogenesis of glomerular and vascular lesions. Kidney Int 7: 242–253

    CAS  PubMed  Google Scholar 

  19. Levy M, Gagnadoux M, Habib R (1980) Pathology of hemolytic uremic syndrome in children. In: G Remuzzi, G Mecca, G dG (eds): Hemostasis, Prostaglandins and Renal Disease. Raven Press, New York, 383–397

    Google Scholar 

  20. Vitsky BH, Suzuki Y, Strauss L, Churg J (1969) The hemolytic-uremic syndrome: a study of renal pathologic alterations. Am J Pathol 57: 627–647

    CAS  PubMed  Google Scholar 

  21. Proia AD, Harden EA, Silberman HR (1984) Mitomycin-induced hemolytic-uremic syndrome. Arch Pathol Lab Med 108: 959–962

    CAS  PubMed  Google Scholar 

  22. Hammar SP, Bloomer HA, McCloskey D (1978) Adult hemolytic uremic syndrome with renal arteriolar deposition of IgM andC3. Am J Clin Pathol 70: 434–439

    CAS  PubMed  Google Scholar 

  23. Hall SM, Glickman M (1988) The British Paediatric Surveillance Unit. Arch Dis Child 63: 344–346

    CAS  PubMed  Google Scholar 

  24. Renaud C, Niaudet P, Gagnadoux MF, Broyer M, Habib R (1995) Haemolytic uraemic syndrome: prognostic factors in children over 3 years of age. Pediatr Nephrol 9: 24–29

    Article  CAS  PubMed  Google Scholar 

  25. Erickson LC, Smith WS, Biswas AK, Camarca MA, Waecker NJ Jr (1994) Streptococcus pneumoniae-induced hemolytic uremic syndrome: a case for early diagnosis. Pediatr Nephrol 8: 211–213

    Article  CAS  PubMed  Google Scholar 

  26. Novak RW, Martin CR, Orsini EN (1983) Hemolytic-uremic syndrome and T-cryptantigen exposure by neuraminidase-producing pneumococci: an emerging problem? Pediatr Pathol 1: 409–413

    CAS  PubMed  Google Scholar 

  27. Leaf AN, Laubenstein LJ, Raphael B, Hochster H, Baez L, Karpatkin S (1988) Thrombotic thrombocytopenic purpura associated with human immunodeficiency virus type 1 (HIV-1) infection. Ann Intern Med 109: 194–197

    CAS  PubMed  Google Scholar 

  28. Dlott JS, Danielson CF, Blue-Hnidy DE, McCarthy LJ (2004) Drug-induced thrombotic thrombocytopenic purpura/hemolytic uremic syndrome: a concise review. Therap Apher Dial 8: 102–111

    CAS  Google Scholar 

  29. Reynolds JC, Agodoa LY, Yuan CM, Abbott KC (2003) Thrombotic microangiopathy after renal transplantation in the United States. Am J Kidney Dis 42: 1058–1068

    PubMed  Google Scholar 

  30. Ruggenenti P (2002) Post-transplant hemolytic-uremic syndrome. Kidney Int 62: 1093–1104

    Article  PubMed  Google Scholar 

  31. Remuzzi G, Ruggenenti P (1995) The hemolytic uremic syndrome. Kidney Int 48: 2–19

    CAS  PubMed  Google Scholar 

  32. George JN (2003) The association of pregnancy with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Curr Opin Hematol 10: 339–344

    Article  PubMed  Google Scholar 

  33. Campbell S, Carre IJ (1965) Fatal haemolytic uraemic syndrome and idiopathic hyperlipaemia in monozygotic twins. Arch Dis Child 40: 654–658

    CAS  PubMed  Google Scholar 

  34. Kaplan BS, Chesney RW, Drummond KN (1975) Hemolytic uremic syndrome in families. N Engl J Med 292: 1090–1093

    CAS  PubMed  Google Scholar 

  35. Berns JS, Kaplan BS, Mackow RC, Hefter LG (1992) Inherited hemolytic uremic syndrome in adults. Am J Kidney Dis 19: 331–334

    CAS  PubMed  Google Scholar 

  36. Noris M, Azzollini N, Mister M, Pezzotta A, Piccinini G, Casiraghi F, Cugini D, Perico N, Orisio S, Remuzzi G (1999) Peripheral donor leukocytes prolong survival of rat renal allografts. Kidney Int 56: 1101–1112

    CAS  PubMed  Google Scholar 

  37. Carreras L, Romero R, Requesens C, Oliver AJ, Carrera M, Clavo M, Alsina J (1981) Familial hypocomplementemic hemolytic uremic syndrome with HLA-A3, B7 haplotype. Jama 245: 602–604

    Article  CAS  PubMed  Google Scholar 

  38. Warwicker P, Goodship TH, Donne RL, Pirson Y, Nicholls A, Ward RM, Turnpenny P, Goodship JA (1988) Genetic studies into inherited and sporadic hemolytic uremic syndrome. Kidney Int 53: 836–844

    Google Scholar 

  39. Petermann A, Offermann G, Distler A, Sharma AM (1998) Familial hemolytic-uremic syndrome in three generations. Am J Kidney Dis 32: 1063–1067

    CAS  PubMed  Google Scholar 

  40. Noris M, Ruggenenti P, Perna A, Orisio S, Caprioli J, Skerka C, Vasile B, Zipfel PF, Remuzzi G (1999) Hypocomplementemia discloses genetic predisposition to hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: role of factor H abnormalities. Italian Registry of Familial and Recurrent Hemolytic Uremic Syndrome/Thrombotic Thrombocytopenic Purpura. J Am Soc Nephrol 10: 281–293

    CAS  PubMed  Google Scholar 

  41. Caprioli J, Castelletti F, Bucchioni S, Bettinaglio P, Bresin E, Pianetti G, Gamba S, Brioschi S, Daina E, Remuzzi G, Noris M (2003) Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: the C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease. Hum Mol Genet 12: 3385–3395

    Article  CAS  PubMed  Google Scholar 

  42. Stuhlinger W, Kourilsky O, Kanfer A, Sraer JD (1974) Letter: Haemolytic-uraemic syndrome: evidence for intravascular C3 activation. Lancet 2: 788–789

    CAS  PubMed  Google Scholar 

  43. Bogdanovic R, Cvoric A, Nikolic V, Sindjic M (1988) Recurrent haemolytic-uraemic syndrome with hypocomplementaemia: a case report. Pediatr Nephrol 2: 236–238

    CAS  PubMed  Google Scholar 

  44. Pichette V, Querin S, Schurch W, Brun G, Lehner-Netsch G, Delage JM (1994) Familial hemolytic-uremic syndrome and homozygous factor H deficiency. Am J Kidney Dis 24: 936–941

    CAS  PubMed  Google Scholar 

  45. Noris M, Brioschi S, Caprioli J, Todeschini M, Bresin E, Porrati F, Gamba S, Remuzzi G (2003) Familial haemolytic uraemic syndrome and an MCP mutation. Lancet 362: 1542–1547

    Article  CAS  PubMed  Google Scholar 

  46. Kim Y, Miller K, Michael AF (1977) Breakdown products of C3 and factor B in hemolytic-uremic syndrome. J Lab Clin Med 89: 845–850

    CAS  PubMed  Google Scholar 

  47. Monnens L, Molenaar J, Lambert PH, Proesmans W, van Munster P (1980) The complement system in hemolytic-uremic syndrome in childhood. Clin Nephrol 13: 168–171

    CAS  PubMed  Google Scholar 

  48. Gonzalo A, Mampaso F, Gallego N, Bellas C, Segui J, Ortuno J (1981) Hemolytic uremic syndrome with hypocomplementemia and deposits of IgM and C3 in the involved renal tissue. Clin Nephrol 16: 193–199

    CAS  PubMed  Google Scholar 

  49. Cossio PM, Laguens RP, Pantin DJ, de Bracco MM, Molinas F, Voyer LE, Arana RM (1977) Persistent glomerulonephritis following the haemolytic-uremic syndrome. Immunopathological and morphological studies. Clin Exp Immunol 29: 361–368

    CAS  PubMed  Google Scholar 

  50. Barre P, Kaplan BS, de Chadarevian JP, Drummond KN (1977) Hemolytic uremic syndrome with hypocomplementemia, serum C3NeF, and glomerular deposits of C3. Arch Pathol Lab Med 101: 357–361

    CAS  PubMed  Google Scholar 

  51. Ohali M, Shalev H, Schlesinger M, Katz Y, Kachko L, Carmi R, Sofer S, Landau D (1998) Hypocomplementemic autosomal recessive hemolytic uremic syndrome with decreased factor H. Pediatr Nephrol 12: 619–624

    Article  CAS  PubMed  Google Scholar 

  52. Walport MJ (2001) Complement. First of two parts. N Engl J Med 344: 1058–1066

    CAS  PubMed  Google Scholar 

  53. Walport MJ (2001) Complement. Second of two parts. N Engl J Med 344: 1140–1144

    CAS  PubMed  Google Scholar 

  54. Neumann HP, Salzmann M, Bohnert-Iwan B, Mannuelian T, Skerka C, Lenk D, Bender BU, Cybulla M, Riegler P, Konigsrainer A et al. (2003) Haemolytic uraemic syndrome and mutations of the factor H gene: a registry-based study of German speaking countries. J Med Genet 40: 676–681

    Article  CAS  PubMed  Google Scholar 

  55. Dragon-Durey MA, Fremeaux-Bacchi V, Loirat C, Blouin J, Niaudet P, Deschenes G, Coppo P, Herman Fridman W, Weiss L (2004) Heterozygous and homozygous factor h deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: report and genetic analysis of 16 cases. J Am Soc Nephrol 15: 787–795

    Article  CAS  PubMed  Google Scholar 

  56. Perez-Caballero D, Gonzalez-Rubio C, Gallardo ME, Vera M, Lopez-Trascasa M, Rodriguez de Cordoba S, Sanchez-Corral P (2001) Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome. Am J Hum Genet 68: 478–484

    CAS  PubMed  Google Scholar 

  57. Rodriguez de Cordoba S, Esparza-Gordillo J, Goicoechea de Jorge E, Lopez-Trascasa M, Sanchez-Corral P (2004) The human complement factor H: functional roles, genetic variations and disease associations. Mol Immunol 41: 355–367

    CAS  PubMed  Google Scholar 

  58. Caprioli J, Bettinaglio P, Zipfel PF, Amadei B, Daina E, Gamba S, Skerka C, Marziliano N, Remuzzi G, Noris M (2001) The molecular basis of familial hemolytic uremic syndrome: mutation analysis of factor H gene reveals a hot spot in short consensus repeat 20. J Am Soc Nephrol 12: 297–307

    CAS  PubMed  Google Scholar 

  59. Buddles MR, Donne RL, Richards A, Goodship J, Goodship TH (2000) Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome. Am J Hum Genet 66: 1721–1722

    Article  CAS  PubMed  Google Scholar 

  60. Richards A, Kemp EJ, Liszewski MK, Goodship JA, Lampe AK, Decorte R, Muslumanoglu MH, Kavukcu S, Filler G, Pirson Y et al. (2003) Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome. Proc Natl Acad Sci USA 100: 12966–12971

    CAS  PubMed  Google Scholar 

  61. Fremeaux-Bacchi V, Dragon-Durey MA, Blouin J, Vigneau C, Kuypers D, Boudailliez B, Loirat C, Rondeau E, Fridman WH (2004) Complement factor I: a susceptibility gene for atypical haemolytic uraemic syndrome. J Med Genet 41: e84

    Article  CAS  PubMed  Google Scholar 

  62. Richards A, Buddles MR, Donne RL, Kaplan BS, Kirk E, Venning MC, Tielemans CL, Goodship JA, Goodship TH (2001) Factor H mutations in hemolytic uremic syndrome cluster in exons 18–20, a domain important for host cell recognition. Am J Hum Genet 68: 485–490

    CAS  PubMed  Google Scholar 

  63. Rougier N, Kazatchkine MD, Rougier JP, Fremeaux-Bacchi V, Blouin J, Deschenes G, Soto B, Baudouin V, Pautard B, Proesmans W et al (1998) Human complement factor H deficiency associated with hemolytic uremic syndrome. J Am Soc Nephrol 9: 2318–2326

    CAS  PubMed  Google Scholar 

  64. Pirson Y, Lefebvre C, Arnout C, van Ypersele de Strihou C (1987) Hemolytic uremic syndrome in three adult siblings: a familial study and evolution. Clin Nephrol 28: 250–255

    CAS  PubMed  Google Scholar 

  65. Landau D, Shalev H, Levy-Finer G, Polonsky A, Segev Y, Katchko L (2001) Familial hemolytic uremic syndrome associated with complement factor H deficiency. J Pediatr 138: 412–417

    CAS  PubMed  Google Scholar 

  66. Hollenbeck M, Kutkuhn B, Aul C, Leschke M, Willers R, Grabensee B (1998) Haemolytic-uraemic syndrome and thrombotic-thrombocytopenic purpura in adults: clinical findings and prognostic factors for death and end-stage renal disease. Nephrol Dial Transplant 13: 76–81

    CAS  PubMed  Google Scholar 

  67. Lara PN Jr, Coe TL, Zhou H, Fernando L, Holland PV, Wun T (1999) Improved survival with plasma exchange in patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Am J Med 107: 573–579

    Article  PubMed  Google Scholar 

  68. Morel-Maroger L, Kanfer A, Solez K, Sraer JD, Richet G (1979) Prognostic importance of vascular lesions in acute renal failure with microangiopathic hemolytic anemia (hemolytic-uremic syndrome): clinicopathologic study in 20 adults. Kidney Int 15: 548–558

    CAS  PubMed  Google Scholar 

  69. Dundas S, Murphy J, Soutar RL, Jones GA, Hutchinson SJ, Todd WT (1999) Effectiveness of therapeutic plasma exchange in the 1996 Lanarkshire Escherichia coli O157:H7 outbreak. Lancet 354: 1327–1330

    Article  CAS  PubMed  Google Scholar 

  70. Tsai HM (2003) Is severe deficiency of ADAMTS-13 specific for thrombotic thrombocytopenic purpura? Yes. J Thromb Haemost 1: 625–631

    PubMed  Google Scholar 

  71. Tsai HM (2003) Deficiency of ADAMTS-13 in thrombotic and thrombocytopenic purpura. J Thromb Haemost 1: 2038–2040; discussion 2040–2035

    PubMed  Google Scholar 

  72. Remuzzi G (2003): Is ADAMTS-13 deficiency specific for thrombotic thrombocytopenic purpura? No. J Thromb Haemost 1: 632–634

    CAS  PubMed  Google Scholar 

  73. Clark WF, Rock GA, Buskard N, Shumak KH, LeBlond P, Anderson D, Sutton DM (1999) Therapeutic plasma exchange: an update from the Canadian Apheresis Group. Ann Intern Med 131: 453–462

    CAS  PubMed  Google Scholar 

  74. Vesely SK, George JN, Lammle B, Studt JD, Alberio L, El-Harake MA, Raskob GE (2003) ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients. Blood 102: 60–68

    Article  CAS  PubMed  Google Scholar 

  75. Tostivint I, Mougenot B, Flahault A, Vigneau C, Costa MA, Haymann JP, Sraer JD, Rondeau E (2002) Adult haemolytic and uraemic syndrome: causes and prognostic factors in the last decade. Nephrol Dial Transplant 17: 1228–1234

    PubMed  Google Scholar 

  76. Ruggenenti P, Galbusera M, Cornejo RP, Bellavita P, Remuzzi G (1993) Thrombotic thrombocytopenic purpura: evidence that infusion rather than removal of plasma induces remission of the disease. Am J Kidney Dis 21: 314–318

    CAS  PubMed  Google Scholar 

  77. Filler G, Radhakrishnan S, Strain L, Hill A, Knoll G, Goodship TH (2004) Challenges in the management of infantile factor H associated hemolytic uremic syndrome. Pediatr Nephrol 19: 908–911

    PubMed  Google Scholar 

  78. Gerber A, Kirchhoff-Moradpour AH, Obieglo S, Brandis M, Kirschfink M, Zipfel PF, Goodship JA, Zimmerhackl LB (2003) Successful (?) therapy of hemolytic-uremic syndrome with factor H abnormality. Pediatr Nephrol 18: 952–955

    Article  PubMed  Google Scholar 

  79. Nathanson S, Fremeaux-Bacchi V, Deschenes G (2001) Successful plasma therapy in hemolytic uremic syndrome with factor H deficiency. Pediatr Nephrol 16: 554–556

    CAS  PubMed  Google Scholar 

  80. Stratton JD, Warwicker P (2002) Successful treatment of factor H-related haemolytic uraemic syndrome. Nephrol Dial Transplant 17: 684–685

    PubMed  Google Scholar 

  81. Remuzzi G, Galbusera M, Salvadori M, Rizzoni G, Paris S, Ruggenenti P (1996) Bilateral nephrectomy stopped disease progression in plasma-resistant hemolytic uremic syndrome with neurological signs and coma. Kidney Int 49: 282–286

    CAS  PubMed  Google Scholar 

  82. Franco A, Hernandez D, Capdevilla L, Errasti P, Gonzalez M, Ruiz JC, Sanchez J (2003) De novo hemolytic-uremic syndrome/thrombotic microangiopathy in renal transplant patients receiving calcineurin inhibitors: role of sirolimus. Transplant Proc 35: 1764–1766

    CAS  PubMed  Google Scholar 

  83. Loirat C, Niaudet P (2003) The risk of recurrence of hemolytic uremic syndrome after renal transplantation in children. Pediatr Nephrol 18: 1095–1101

    Article  PubMed  Google Scholar 

  84. Artz MA, Steenbergen EJ, Hoitsma AJ, Monnens LA, Wetzels JF (2003) Renal transplantation in patients with hemolytic uremic syndrome: high rate of recurrence and increased incidence of acute rejections. Transplantation 76: 821–826

    PubMed  Google Scholar 

  85. Ferraris JR, Ramirez JA, Ruiz S, Caletti MG, Vallejo G, Piantanida JJ, Araujo JL, Sojo ET (2002) Shiga toxin-associated hemolytic uremic syndrome: absence of recurrence after renal transplantation. Pediatr Nephrol 17: 809–814

    Article  PubMed  Google Scholar 

  86. Miller RB, Burke BA, Schmidt WJ, Gillingham KJ, Matas AJ, Mauer M, Kashtan CE (1997) Recurrence of haemolytic-uraemic syndrome in renal transplants: a single-centre report. Nephrol Dial Transplant 12: 1425–1430

    CAS  PubMed  Google Scholar 

  87. Donne RL, Abbs I, Barany P, Elinder CG, Little M, Conlon P, Goodship TH (2002) Recurrence of hemolytic uremic syndrome after live related renal transplantation associated with subsequent de novo disease in the donor. Am J Kidney Dis 40: E22

    Article  PubMed  Google Scholar 

  88. Remuzzi G, Ruggenenti P, Codazzi D, Noris M, Caprioli J, Locatelli G, Gridelli B (2002) Combined kidney and liver transplantation for familial haemolytic uraemic syndrome. Lancet 359: 1671–1672

    Article  PubMed  Google Scholar 

  89. Remuzzi G, Ruggenenti P, Colledan M, Gridelli B, Bertani A, Bettinaglio P, Bucchioni S, Sonzogni A, Bonanomi E, Sonzogni V et al. (2005) Hemolytic uremic syndrome: a fatal outcome after kidney and liver transplantation performed to correct factor H gene mutation. Am J Transplant 5: 1146–1150

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Transplant Research Center “Chiara Cucchi de Alessandri e Gilberto Crespi”, Mario Negri Institute for Pharmacological Research, Villa Camozzi, via Camozzi, 3, 24020, Ranica, Bergamo, Italy

    Marina Noris1 & Giuseppe Remuzzi

  2. Department of Medicine and Transplantation, Ospedali Riuniti di Bergamo, Largo Barozzi 1, 24128, Bergamo, Italy

    Giuseppe Remuzzi

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  1. Marina Noris1
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  2. Giuseppe Remuzzi
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  1. Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Beutenbergstr. 11a, D-07745, Jena, Germany

    Peter F. Zipfel

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Noris1, M., Remuzzi, G. (2006). Non-Shiga toxin-associated hemolytic uremic syndrome. In: Zipfel, P.F. (eds) Complement and Kidney Disease. Progress in Inflammation Research. Birkhäuser Basel. https://doi.org/10.1007/3-7643-7428-4_5

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