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References

  1. Libby P (2002) Atherosclerosis: the new view. Sci Am 286: 46–55

    PubMed  Google Scholar 

  2. Russell ME (1997) Graft arteriosclerosis: molecular features of macrophage activation. Transplant Proc 29: 2542–2543

    PubMed  CAS  Google Scholar 

  3. Cipollone F, Marini M, Fazia M, Pini B, Iezzi A, Reale M, Paloscia L, Materazzo G, D’Annunzio E, Conti P et al. (2001) Elevated circulating levels of monocyte chemoattractant protein-1 in patients with restenosis after coronary angioplasty. Arterioscler Thromb Vasc Biol 21: 327–334

    PubMed  CAS  Google Scholar 

  4. Nicholson AC, Han J, Febbraio M, Silversterin RL, Hajjar DP (2001) Role of CD36, the macrophage class B scavenger receptor, in atherosclerosis. Ann NY Acad Sci 947: 224–228

    PubMed  CAS  Google Scholar 

  5. Plump AS, Smith JD, Hayek T, Aalto-Setala K, Walsh A, Verstuyft JG, Rubin EM, Breslow JL (1992) Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 71: 343–353

    Article  PubMed  CAS  Google Scholar 

  6. Buono C, Pang H, Uchida Y, Libby P, Sharpe AH, Lichtman AH (2004) B7-1/B7-2 costimulation regulates plaque antigen-specific T-cell responses and atherogenesis in lowdensity lipoprotein receptor-deficient mice. Circulation 109: 2009–2015

    Article  PubMed  CAS  Google Scholar 

  7. gano H, Libby P, Taylor MK, Hasegawa S, Stinn JL, Becker G, Tilney NL, Mitchell RN (1998) Coronary arteriosclerosis after T-cell-mediated injury in transplanted mouse hearts: role of interferon-gamma. Am J Pathol 152: 1187–1197

    Google Scholar 

  8. Li L, Lee EW, Ji H, Zukowska Z (2003) Neuropeptide Y-induced acceleration of postangioplasty occlusion of rat carotid artery. Arterioscler Thromb Vasc Biol 23: 1204–1210

    PubMed  CAS  Google Scholar 

  9. Zukowska-Grojec Z, Konarska M, McCarty R (1988) Differential plasma catecholamine and neuropeptide Y responses to acute stress in rats. Life Sci 42: 1615–1624

    Article  PubMed  CAS  Google Scholar 

  10. Zukowska-Grojec Z, Dayao EK, Karwatowska-Prokopczuk E, Hauser GJ, Doods HN (1996) Stress-induced mesenteric vasoconstriction in rats is mediated by neuropeptide Y Y1 receptors. Am J Physiol 270: H796–H800

    PubMed  CAS  Google Scholar 

  11. Wahlestedt C, Hakanson R, Vaz CA, Zukowska-Grojec Z (1990) Norepinephrine and neuropeptide Y: vasoconstrictor cooperation in vivo and in vitro. Am J Physiol 258: R736–R742

    PubMed  CAS  Google Scholar 

  12. Pons J, Kitlinska J, Ji H, Lee EW, Zukowska Z (2003) Mitogenic actions of neuropeptide Y in vascular smooth muscle cells: synergetic interactions with the beta-adrenergic system. Can J Physiol Pharmacol 81: 177–185

    Article  PubMed  CAS  Google Scholar 

  13. Erlinge D, Brunkwall J, Edvinsson L (1994) Neuropeptide Y stimulates proliferation of human vascular smooth muscle cells: cooperation with noradrenaline and ATP. Regul Pept 50: 259–265

    Article  PubMed  CAS  Google Scholar 

  14. Laurent S, Vanhoutte P, Cavero I, Chabrier PE, Dupuis B, Elghozi JL, Hamon G, Janiak P, Juillet Y, Kher A et al (1996) The arterial wall: a new pharmacological and therapeutic target. Fundam Clin Pharmacol 10: 243–257

    PubMed  CAS  Google Scholar 

  15. Zukowska-Grojec Z, Karwatowska-Prokopczuk E, Rose W, Rone J, Movafagh S, Ji H, Yeh Y, Chen WT, Kleinman HK, Grouzmann E et al (1998) Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium. Circ Res 83: 187–195

    PubMed  CAS  Google Scholar 

  16. De la Fuente M, Bernaez I, Del Rio M, Hernanz A (1993) Stimulation of murine peritoneal macrophage functions by neuropeptide Y and peptide YY. Involvement of protein kinase C. Immunology 80: 259–265

    PubMed  Google Scholar 

  17. Kalra SP, Clark JT, Sahu A, Dube MG, Kalra PS (1988) Control of feeding and sexual behaviors by neuropeptide Y: physiological implications. Synapse 2: 254–257

    Article  PubMed  CAS  Google Scholar 

  18. Bedoui S, Miyake S, Lin Y, Miyamoto K, Oki S, Kawamura N, Beck-Sickinger A, Von Horsten S, Yamamura T (2003) Neuropeptide Y (NPY) suppresses experimental autoimmune encephalomyelitis: NPY(1) receptor-specific inhibition of autoreactive Th1 responses in vivo. J Immunol 171: 3451–3458

    PubMed  CAS  Google Scholar 

  19. Zukowska Z, Grant DS, Lee EW (2003) Neuropeptide y. A novel mechanism for ischemic angiogenesis. Trends Cardiovasc Med 13: 86–92

    Article  PubMed  CAS  Google Scholar 

  20. Karvonen MK, Pesonen U, Koulu M, Niskanen L, Laakso M, Rissanen A, Dekker JM, Hart LM, Valve R, Uusitupa MI (1998) Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels. Nat Med 4: 1434–1437

    Article  PubMed  CAS  Google Scholar 

  21. Kallio J, Pesonen U, Kaipio K, Karvonen MK, Jaakkola U, Heinonen OJ, Uusitupa MI, Koulu M (2001) Altered intracellular processing and release of neuropeptide Y due to leucine 7 to proline 7 polymorphism in the signal peptide of preproneuropeptide Y in humans. Faseb J 15: 1242–1244

    PubMed  CAS  Google Scholar 

  22. Karvonen MK, Valkonen VP, Lakka TA, Salonen R, Koulu M, Pesonen U, Tuomainen TP, Kauhanen J, Nyyssonen K, Lakka HM et al. (2001) Leucine7 to proline7 polymorphism in the preproneuropeptide Y is associated with the progression of carotid atherosclerosis, blood pressure and serum lipids in Finnish men. Atherosclerosis 159: 145–151

    Article  PubMed  CAS  Google Scholar 

  23. Zukowska-Grojec Z (1995) Neuropeptide Y. A novel sympathetic stress hormone and more. Ann NY Acad Sci 771: 219–233

    CAS  Google Scholar 

  24. Bedoui S, Lechner S, Gebhardt T, Nave H, Beck-Sickinger AG, Straub RH, Pabst R, von Horsten S (2002) NPY modulates epinephrine-induced leukocytosis via Y-1 and Y-5 receptor activation in vivo: sympathetic co-transmission during leukocyte mobilization. J Neuroimmunol 132: 25–33

    Article  PubMed  CAS  Google Scholar 

  25. Medina S, Del Rio M, Ferrandez MD, Hernanz A, De la Fuente M (1998) Changes with age in the modulation of natural killer activity of murine leukocytes by gastrin-releasing peptide, neuropeptide Y and sulfated cholecystokinin octapeptide. Neuropeptides 32: 549–555

    Article  PubMed  CAS  Google Scholar 

  26. Myers AK, Farhat MY, Vaz CA, Keiser HR, Zukowska-Grojec Z (1988) Release of immunoreactive-neuropeptide Y by rat platelets. Biochem Biophys Res Commun 155: 118–122

    Article  PubMed  CAS  Google Scholar 

  27. Berglund MM, Hipskind PA, Gehlert DR (2003) Recent developments in our understanding of the physiological role of PP-fold peptide receptor subtypes. Exp Biol Med (Maywood) 228: 217–244

    CAS  Google Scholar 

  28. Ericsson A, Schalling M, McIntyre KR, Lundberg JM, Larhammar D, Seroogy K, Hokfelt T, Persson H (1987) Detection of neuropeptide Y and its mRNA in megakaryocytes: enhanced levels in certain autoimmune mice. Proc Natl Acad Sci USA 84: 5585–5589

    PubMed  CAS  Google Scholar 

  29. Ogawa T, Kitamura K, Kangawa K, Matsuo H, Eto T (1992) Platelet neuropeptide Y in spontaneously hypertensive rats. J Hypertens 10: 765–771

    PubMed  CAS  Google Scholar 

  30. Myers AK, Torres Duarte AP, Zukowska-Grojec Z (1993) Immunoreactive neuropeptide Y (NPY) in plasma and platelets of rat and mouse strains and human volunteers. Regul Pept 47: 239–245

    Article  PubMed  CAS  Google Scholar 

  31. Wagner DD (2005) New links between inflammation and thrombosis. Arterioscler Thromb Vasc Biol 25: 1321–1324

    PubMed  CAS  Google Scholar 

  32. Carmeliet P, Collen D (1997) Molecular genetics of the fibrinolytic and coagulation systems in haemostasis, thrombogenesis, restenosis and atherosclerosis. Curr Opin Lipidol 8: 118–125

    PubMed  CAS  Google Scholar 

  33. Nilsson C, Karlsson G, Blennow K, Heilig M, Ekman R (1996) Differences in the neuropeptide Y-like immunoreactivity of the plasma and platelets of human volunteers and depressed patients. Peptides 17: 359–362

    Article  PubMed  CAS  Google Scholar 

  34. Lewandowski J, Pruszczyk P, Wocial B, Ignatowska-Switalska H, Romejko-Woniewicz E, Madej-Firek A, Januszewicz W, Zukowska-Grojec Z (1996) Sex hormone modulation of neuropeptide Y and cardiovascular responses to stress in humans. In: R McCarty, G Aguilera, E Sabban, R Kvetnansky (eds): Stress: Molecular and Neurobiological Advances. Gordon and Breach Science Publishers S.A., New York, USA, 569–578

    Google Scholar 

  35. Dutton MA, Lee EW, Zukowska Z (2005) NPY and extreme stress: lessons learned from posttraumatic stress disorder. In: Z Zukowska, GZ Feuerstein (eds): NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics. Birkhäuser Publishing Ltd., Basel, Switzerland

    Google Scholar 

  36. Merten N, Beck-Sickinger AG (2005) Molecular ligand-receptor interaction of the NPY/PP peptide family. In: Z Zukowska, GZ Feuerstein (eds): NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics. Birkhäuser Publishing Ltd., Basel, Switzerland

    Google Scholar 

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Li, L., Abe, K., Lee, E.W., Zukowska, Z. (2005). NPY in vascular inflammation, remodeling and atherosclerosis. In: Zukowska, Z., Feuerstein, G.Z. (eds) The NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis and Cancer. Progress in Inflammation Research. Birkhäuser Basel. https://doi.org/10.1007/3-7643-7427-6_11

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