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Chapter 13
Cotton, R.G.H., Milstein. C. 1973. Fusion of two immunoglobulin-producing myeloma cells. Nature 244: 42.
Grosschedl, R., Weaver, D., Baltimore, D., Costantini, F. 1984. Introduction of a mu immunoglobulin gene into the mouse germ line: specific expression in lymphoid cells and synthesis of functional antibody. Cell 38:647.
Storb, U., O’Brien, R.L., McMullen, M.D., Gollahon, K.A., Brinster, R.L. 1984. High expression of cloned immunoglobulin kappa gene in transgenic mice is restricted to B lymphocytes. Nature 310:238.
Ochi, A., Hawley, R.G., Hawley, T., Shulman, M.J., Traunecker, A., Köhler, G., Hozumi, N. 1983. Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells. Proc. Nat. Acad. Sci. USA 80:6351.
Rusconi, S., Köhler, G. 1985. Transmission and expression of a specific pair of rearranged immunoglobulin mu and kappa genes in a transgenic mouse line. Nature 314:330.
Leder. P. 1982. The genetics of antibody diversity. Sci. Am. 246:108.
Kindt, T. Capra, J.D. 1984. The antibody enigma. Plenum Press, New York, London
Janeway, C.A. Jr., Travers, P., Walpot, M., Shlomchik, M.J. 2005. Immunobiology, the immune system in health and disease. 6th edition. GS Garland Science, New York, London.
Kottmann, A.H., Brack, C., Eibel, H., Köhler, G. 1992. A survey of protein-DNA interaction sites within the murine immunoglobulin heavy chain locus reveals a particularly complex pattern around the DQ52 element. Eur. J. Immunol. 22:2113.
Kottmann, A, H., Zevnik, B., Welte, M., Nielsen, P.J., Köhler G. 1994. A second promoter and enhancer element within the immunoglobulin heavy chain locus. Eur. J. Immunol. 24:817.
Iglesias, A., Lamers, M., Köhler, G. 1987. Expression of immunoglobulin delta chain causes allelic exclusion in transgenic mice. Nature 330:482.
Köhler, G. 1989. Allelic exclusion-one facet of B-cell development. Immunol. Today 10:11.
Melchers, F., ten Boekel, E., Yamagami, T., Andersson, J., Rolink, A. 1999. The roles of preB and B cell receptors in the stepwise allelic exclusion of mouse IgH and L chain gene loci. Semin. Immunol. 11:307
Loffert, D., Schaal, S., Ehlich, A., Hardy, R.R., Zou, Y.R., Muller, W., Rajewsky, K. 1994. Early B-cell development in the mouse: insights from mutations introduced by gene targeting. Immunol. Rev. 137:135.
Nitschke, L., Kosco, M.H., Köhler, G., Lamers, M.C. 1993. Immunoglobulin D-deficient mice can mount normal immune responses to thymus-independent and-dependent antigens. Proc. Nat. Acad. Sci. USA 90:1887.
Rammensee, H.G., Julius, M.H., Nemazee, D., Langhorne, J., Lamers, R., Köhler, G. 1987. Targeting cytotoxic T cells to antigen-specific B lymphocytes. Eur. J. Immunol. 17:433.
Julius, M.H., Rammensee, H.G., Ratcliffe, M.J., Lamers, M.C., Langhorne, J., Köhler, G. 1988. The molecular interactions with helper T cells which limit antigen-specific B cell differentiation. Eur. J. Immunol. 18:381.
Brombacher, F., Lamers, M.C., Köhler, G., Eibel, H. 1989. Elimination of CD8+ thymocytes in transgenic mice expressing an anti-Lyt2.2 immunoglobulin heavy chain gene. EMBO J. 8:3719.
Brombacher, F., Köhler, G., Eibel, H. 1991. B cell tolerance in mice transgenic for anti-CD8 immunoglobulin mu chain. J. Exp. Med. 174:1335.
Theopold, U., Köhler, G. 1990. Partial tolerance in beta-galactosidase-transgenic mice. Eur. J. Immunol. 20:1311.
Goodnow, C.C., Crosbie, J., Adelstein, S., Lavoie, T.B., Smith-Gill, S.J., Brink, R.A., Pritchard-Briscoe, H., Wotherspoon, J.S., Loblay, R.H., Raphael, K, et al. 1988. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334:676.
Nemazee, D.A., Burki, K. 1989. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature 337:562.
Götz, J., Eibel, H., Köhler, G. 1990. Non-tolerance and differential susceptibility to diabetes in transgenic mice expressing major histocompatibility class II genes on pancreatic beta cells. Eur. J. Immunol. 20:1677.
Allison, J., Campbell, I.L., Morahan, G., Mandel, T.E., Harrison, L.C., Miller, J.F. 1988. Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic beta cells. Nature 333:529.
Lo, D., Burkly, L.C., Widera, G., Cowing, C., Flavell, R.A., Palmiter, R.D., Brinster, R.L. 1988. Diabetes and tolerance in transgenic mice expressing class II MHC moleculein pancreatic beta cells. Cell 53:159.
Sarvetnick, N., Liggitt, D., Pitts, S.L., Hansen, S.E., Stewart, T.A. 1988. Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma. Cell 52:773.
Bohme, J., Haskins, K., Stecha, P., van Ewijk, W., LeMeur M., Gerlinger, P., Benoist, C., Mathis, D. 1989. Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant. Science 244:1179.
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(2005). Post-Nobel science I. In: Köhler’s Invention. Birkhäuser Basel. https://doi.org/10.1007/3-7643-7413-6_13
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DOI: https://doi.org/10.1007/3-7643-7413-6_13
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