Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Shaham Y, Shalev U, Lin L, de Wit H, Stewart J (2003) The reinstatement model of drug relapse: history, methodoloy and major findings. Psychopharmacology 168: 3–20
Spanagel R (2003) Alcohol addiction research: From animal models to clinics. Best Pract Res Cl GA 17: 507–518
Tzschentke T (2005) Measuring reward with conditioned place preference: an up-date of the literature. Addict Biol; in press
Everitt BJ, Robbins TW (2000) Second-order schedules of drug reinforcement in rats and monkeys: measurement of reinforcing efficacy and drug-seeking behaviour. Psychopharmacology 153: 17–30
Ahmed SH, Koob GF (1998) Transition from moderate to excessive drug intake: change in hedonic set point. Science 282: 298–300
van der Kooy D, O’Shaughnessy M, Mucha RF, Kalant H (1983) Motivational properties of ethanol in naive rats as studied by place conditioning. Pharmacol Biochem Behav 19: 441–445
Cunningham CL, Niehus DR, Malott DH, Prather LK (1992) Genetic differences in the rewarding and activating effects of morphine and ethanol. Psychopharmacology 107: 385–393
Chiamulera C, Valerio E, Tessari M (1995) Resumption of ethanol-seeking behaviour in rats. Behav Pharmacol 6: 32–39
Ludwig AM, Wikler A, Stark LH (1974) The first drink: psychobiological aspects of craving. Arch Gen Psychiatry 30: 539–547
Besancon F (1993) Time to alcohol dependence after abstinence and first drink. Addiction 88: 1647–1650
de Wit H, Chutuape MA (1993) Increased ethanol choice in social drinkers following ethanol preload. Behav Pharmacol 4: 29–36
Lê AD, Quan B, Juzytch W et al. (1998) Reinstatement of alcohol-seeking by priming injections of alcohol and exposure to stress in rats. Psychopharmacology 135: 169–174
Katner SN, Magalong JG, Weiss F (1999) Reinstatement of alcohol-seeking behavior by drug-associated discriminative stimuli after prolonged extinction in the rat. Neuropsychopharmacology 20: 471–479
Liu X, Weiss F (2002) Addictive effect of stress and drug cues on reinstatement of ethanol seeking: exacerbation by history of dependence and role of concurrent activation of corticotropin-releasing factor and opioid mechanisms. J Neurosci 22: 7856–7861
Spanagel R, Sanchis-Segura C (2003) The use of transgenic mice to study addictive behavior. Clin Neurosci Res 3: 325–331
Bachteler D, Economidou D, Danysz W, Ciccocioppo R, Spanagel R (2005) The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behaviour. Neuropsychopharmacology; in press
Lê AD, Poulos CX, Harding S, Watchus J, Juzytsch W, Shaham Y (1999) Effects of naltrexone and fluoxetine on alcohol self-administration and reinstatement of alcohol seeking induced by priming injections of alcohol and exposure to stress. Neuropsychopharmacology 21: 435–444
Spanagel R, Hölter SM (2000) Controversial research areas: a critical review. In: G Zernig, A Saria, A Kurz (eds): Handbook of Alcoholism: Clinical and Theoretical Approaches. CRC Press, Boca Raton, Fl, 401–416
Sinclair JD (1997) The alcohol-deprivation effect in monkeys. Psychonom Sci 25: 21–25
Burish TG, Maisto SA, Cooper AM, Sobell MB (1981) Effects of voluntary short-term abstinence from alcohol on subsequent drinking patterns of college students. J Stud Alcohol 42: 1013–1020
Rodd-Henricks ZA, McKinzie DL, Murphy JM et al. (2000) The expression of an alcohol deprivation effect in the high-alcohol-drinking replicate rat lines is dependent on repeated deprivations. Alcohol Clin Exp Res 24: 747–753
Rodd-Henricks ZA, McKinzie DL, Shaikh SR et al. (2000) Alcohol deprivation effect is prolonged in the alcohol preferring (P) rat after repeated deprivations. Alcohol Clin Exp Res 24: 8–16
Spanagel R, Hölter SM (1999) Long-term alcohol self-administration with repeated alcohol deprivation phases: an animal model of alcoholism? Alcohol Alcoholism 34: 231–243
Spanagel R, Pendyala G, Abarca C et al. (2004) The circadian clock gene period2 alters the glutamatergic system and thereby modulates alcohol consumption. Nature Med; in press
Salimov RM, Salimova NB (1993) The alcohol-deprivation effect in hybrid mice. Drug Alcohol Depend 32: 187–191
Salimov RM, Salimova NB, Shvets LN, Maisky AI (2000) Haloperidol administered subchronically reduces the alcohol-deprivation effect in mice. Alcohol 20: 61–68
Cowen MS, Schroff KC, Gass P, Sprengel R, Spanagel R (2003) Neurobehavioral effects of alcohol in AMPA receptor subunit (GluR1) deficient mice. Neuropharmacology 45: 325–333
Cowen M, Schumann G, Yagi, Spanagel R (2003) Role of Fyn tyrosine kinase in ethanol consumption by mice. Alcohol Clin Exp Res 27: 1213–1219
Spanagel R, Hölter SM (2000) Pharmacological validation of a new animal model of alcoholism. J Neural Transm 107: 669–680
Spanagel R, Sanchis-Segura C (2005) Basic considerations for random ENU mutagenesis in combination with an alcohol screen test. Addict Biol; in press
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Birkhäuser Verlag/Switzerland
About this chapter
Cite this chapter
Spanagel, R. (2005). How to measure relapse in animals. In: Spanagel, R., Mann, K.F. (eds) Drugs for Relapse Prevention of Alcoholism. Milestones in Drug Therapy MDT. Birkhäuser Basel. https://doi.org/10.1007/3-7643-7305-9_2
Download citation
DOI: https://doi.org/10.1007/3-7643-7305-9_2
Publisher Name: Birkhäuser Basel
Print ISBN: 978-3-7643-0214-6
Online ISBN: 978-3-7643-7305-4
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)