Abstract
In this paper we consider graph traversal problems that arise from a particular technology for DNA sequencing — sequencing by hybridization (SBH). We first explain the connection of the graph problems to SBH and then focus on the traversal problems. We describe a practical polynomial time solution to the Travelling Salesman Problem in a rich class of directed graphs (including edge weighted binary de Bruijn graphs), and provide a bounded-error approximation algorithm for the maximum weight TSP in a superset of those directed graphs. We also establish the existence of a matroid structure defined on the set of Euler and Hamilton paths in the restricted class of graphs.
Partially supported by Department of Energy grant DE-FG03-90ER60999.
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© 1996 Springer-Verlag Berlin Heidelberg
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Gusfield, D., Karp, R., Wang, L., Stelling, P. (1996). Graph traversals, genes, and matroids: An efficient case of the travelling salesman problem. In: Hirschberg, D., Myers, G. (eds) Combinatorial Pattern Matching. CPM 1996. Lecture Notes in Computer Science, vol 1075. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-61258-0_22
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DOI: https://doi.org/10.1007/3-540-61258-0_22
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