Abstract
Lipid assemblies are arrays of noncovalently associated amphiphiles, i.e. supramolecular assemblies. They may be classified as supported or self-supported assmeblies. The advent of methods to polymerize these supramolecular assemblies has opened up opportunities for the creation of new materials. This review emphasizes the interaction of polymerization and lipid domain formation within supramolecular assemblies. The polymerization of amphiphilic assemblies can “lock in” preexisting lipid domains or create lipid domains from random mixtures depending on the nature of the polymerizable amphiphile. Lipid diacetylenes or fluorinated lipids provide a convenient means to form an unpolymerized immiscible mixture of reactive and nonreactive lipids in monolayers or bilayers. In contrast the polymerization of dienoyl-, sorbyl-, or acryloyl-substituted lipids can effectively induce the phase separation of unreactive lipids from the growing polymeric domains. Polymerization-induced lipid domains can endow bilayer vesicles with latent instability sites or can be used to concentrate membrane-associated electron or energy transfer cofactors. These polymeric materials suggest new approaches to the delivery of reagents as well as the transduction of light energy.
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5 References
Ringsdorf H, Schlar B, Venzmer J (1988) Angew Chem Int Ed Engl 27: 113
O'Brien DF (1994) Trends Polym Sci 2: 183
Lee Y-S, Yang J-Z, Sisson TM, Frankel DA, Gleeson JT, Aksay E, Keller SL, Gruner SM, O'Brien DF (1995) J Am Chem Soc 117: 5573.
Singer SJ, Nicolson GL (1972) Science 175: 720
Möhwald H (1990) Annu Rev Phys Chem 41: 441
McConnell H (1991) Annu Rev Phys Chem 42: 171
Chi LF, Anders M, Fuchs H, Johnson RR, Ringsdorf H (1993) Science 259: 213
Klausner RD, Kleinfeld AM (1984) In: Perelson AS, DeLisi C, Wiegel FW (eds). Cell Surface Dynamics. Marcel Dekker, New York, p 23
McElhaney RN (1982) Chem Phys Lipids 30: 229
Krisovitch SM, Regen SL (1992) J Am Chem Soc 114: 9828
Silvius JR (1986) Biochim Biophys Acta 857: 217
Sankaram MB, Marsh D, Thompson TE (1992) Biophys J 63: 340
Singh A, Schnur JM (1993) In: Cevc G (ed). Phospholipids Handbook. Marcel Dekker, NY, p 233
O'Brien DF, Ramaswami V (1989) Encyclopedia of Polymer Science and Engineering 17: 108
Fahey PF, Webb WW (1978) Biochemistry 17: 3046
Sells TD, O'Brien DF (1991) Macromolecules 24: 336
Sells TD, O'Brien DF (1994) Macromolecules 27: 226
Lei J, O'Brien DF (1994) Macromolecules 27: 1381
Lamparski H, O'Brien DF (1995) Macromolecules 28: 1786
Hitchcock PB, Mason R, Thomas KM, Shipley GG (1974) Proc Natl Acad Sci USA 71: 3036
Haberkorn RA, Griffin RG, Meadows MD, Oldfield E (1977) J Am Chem Soc 99: 7353
Hauser H, Pascher I, Pearson RH, Sundell S (1981) Biochim Biophys Acta 650: 21
Lopez E, O'Brien DF, Whitesides TH (1982) J Am Chem Soc 104: 305
Kölchens S, Lamparski H, O'Brien DF (1993) Macromolecules 26: 398
Helenius A, Simons K (1975) Biochim Biophys Acta 415: 29
Lichtenberg D, Robson R, Dennis EA (1983) Biochim Biophys Acta 737: 285
Regen SL, Singh A, Oehme G, Singh M (1982) J. Am Chem Soc 104: 791
Tsuchida E, Hasegawa E, Kimura N, Hatashita M, Makino C (1992) Macromolecules 25: 207
Sisson T, Lamparski HG, Kölchens S, Elyadi A, O'Brien DF, (unpublished observations)
Stein WD (1986) Transport and Diffusion Across Cell Membranes, Academic Press, San Diego, CA
Dorn K, Klingbiel RT, Specht DP, Tyminski PN, Ringsdorf H, O'Brien DF (1984) J Am Chem Soc 106: 1627
Büschl R, Ringsdorf H, O'Brien DF (unpublished observations)
Hupfer B, Ringsdorf H, Schupp H (1981) Makromol Chem 182: 247
Crisp DJ (1967) In: Surface Chemistry. Butterworth's London: Proc Joint Meeting Faraday Soc Chem Phys 1944
Wegner G (1972) Makromol Chem 154: 35
Büschl R, Hupfer B, Ringsdorf H (1982) Makromol Chem Rapid Commun 3: 589
Lopez E, O'Brien DF, Whitesides TH (1982) Biochim Biophys Acta 693: 437
Sackmann E, Eggl P, Fahn C, Bader H, Ringsdorf H, Schollmeier M (1985) Ber Bunsenges Phys Chem 89: 1198
Elbert R, Folda T, Ringsdorf H (1984) J Am Chem Soc 106: 7687
Mimms LT, Zampighi G, Nozaki Y, Tanford C, Reynolds JA (1981) Biochemistry 20: 833
Büschl R, Folda T, Ringsdorf H (1984) Makromol Chem 6: 245
Gaub H, Büschl R, Ringsdorf H, Sackmann E (1985) Chem Phys Lipids 37: 19
Gaub H, Sackmann E, Büschl R, Ringsdorf H (1984) Biophys J 45: 725
Dorn K, Patton EV, Klingbiel RT, O'Brien DF, Ringsdorf H (1983) Makro Chem Rapid Commun 4: 513
Seki N, Tsuchida E, Ukaji K, Sekiya T, Nozawa Y (1985) Polym Bull 13: 489
Tsuchida E, Seki N, Ohno H (1986) Makromol Chem 187: 1351
Elbert R, Laschewsky A, Ringsdorf H (1985) J Am Chem Soc 107: 4134
Ohno H, Takeoka S, Tsuchida E (1985) Polym Bull 14: 487
Takeoka S, Sakai H, Ohno H, Tsuchida E (1991) Macromolecules 24: 1279
Dennis ED (1983) In: Boyer PD (ed.) The Enzymes, 3rd Edn. Academic Press, New York 16: 307
Büschl R (1984) PhD Dissertation, Universität Mainz
Tsuchida E, Seki N, Ohno H (1986) Makromol Chem 187: 1351
Grainger DW, Reichert A, Ringsdorf H, Salesse C, Davies DE, Lloyd JB (1990) Biochim Biophys Acta 1022: 146
Ahlers M, Muller W, Reichert A, Ringsdorf H, Venzmer J (1990) Angew Chem Int Ed Engl 29: 1269
Tyminski PN, Latimer LH, O'Brien DF (1985) J Am Chem Soc 107: 7769
Tyminski PN, Latimer LH, O'Brien DF (1988) Biochemistry 27: 2696
Kuhn H (1980) Nature (London) 283: 587
Tyminski PN, O'Brien DF (1984) Biochemistry 23: 3986
Frankel DA, Lamparski H, Liman U, O'Brien DF (1989) J Am Chem Soc 111: 9262
Lamparski H, Liman U, Frankel DA, Barry JA, Ramaswami V, Brown MF, O'Brien DF (1992) Biochemistry 31: 685
Tyminski PN, Ponticello IS, O'Brien DF (1987) J Am Chem Soc 109: 6541
Szoka FC, Papahadjopoulos D (1978) Proc Natl Acad Sci USA 75: 4198
Hope MJ, Bally MB, Webb G, Cullis PR (1985) Biochim Biophys Acta 812: 55
Mayer LD, Hope MJ, Cullis PR (1986) Biochim Biophys Acta 858: 161
Ellens H, Bentz J, Szoka FC (1984) Biochemistry 23: 1532
Ellens H, Bentz J, Szoka FC (1986) Biochemistry 25: 4141
Ellens H, Bentz J, Szoka FC (1986) Biochemistry 25: 285
Parsegian VA, Fuller N, Rand RP (1979) Proc Natl Acad Sci USA 76: 2750
Siegel DP (1986) Biophys J 49: 1155
Siegel DP (1986) Biophys J 49: 1171
Siegel DP (1993) Biophys J 65: 2124
Cullis PR, DeKruijff B (1979) Biochim Biophys Acta 559: 399
Barry JA, Lamparski H, Shyamsunder E, Osterberg F, Cerne J, Brown MF, O'Brien DF (1992) Biochemistry 31: 10114
Bennett DE, O'Brien DF (1995) Biochemistry 34: 3102
Bentz J, Nir S, Wilschut J (1983) Colloids Surf 6: 333
Gruner SM (1985) Proc Natl Acad Sci 82: 3665
Gruner SM (1989) J Phys Chem 93: 7562
Eggl P, Pink D, Quinn B, Ringsdorf H, Sackmann E (1990) Macromolecules 23: 3472
Armitage BA, Klekotka PA, Oblinger E, O'Brien DF (1993) J Am Chem Soc 115: 7920
Balzani V, Scandola F (1991) Supramolecular Photochemistry, Ellis Harwood, New York
Clapp PJ, Armitage BA, Roosa P, O'Brien DF (1994) J Am Chem Soc 116: 9166
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Armitage, B.A., Bennett, D.E., Lamparski, H.G., O'Brien, D.F. (1996). Polymerization and domain formation in lipid assemblies. In: Biopolymers Liquid Crystalline Polymers Phase Emulsion. Advances in Polymer Science, vol 126. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-60484-7_2
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DOI: https://doi.org/10.1007/3-540-60484-7_2
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