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Field evaluations of a knowledge-based system for peripheral blood interpretation

  • Diamond L. W. 
  • Nguyen D. T. 
  • Ralph P. 
  • Sheridan B. 
  • Bak A. 
  • Kessler C. 
  • Muncer D. 
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 934)

Abstract

A medical knowledge-based system for hemogram and peripheral blood smear interpretation was tested in three situations outside of the developers' laboratory: Coulter Corporation's Clinical Evaluations, and two clinical laboratories in the United States and Canada. Rigorous testing of the system's functionality was performed. Hazard testing caught several programming errors which were corrected. The outside evaluators requested a number of changes to the screens and additional functionality. As a result, several user configurable features were added to the system. Medical information collected from 13 of 392 (3.3%) cases effected the knowledge base. Only two of the evaluator's comments concerned the style of the system's displayed output. The system was able to maintain high quality interpretive reports, appropriate to patient care, despite the expected differences in subjective morphologic interpretation between observers.

Keywords

Hard Disk Drive Blood Film Manual Differential Peripheral Blood Film Patient Identification Number 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. [1]
    Wyatt J. Field trials of medical decision-aids: potential problems and solutions. In: Fifteenth Annual Symposium on Computer Applications in Medical Care. NewYork: McGraw-Hill 1992;3–7.Google Scholar
  2. [2]
    Wyatt J, Spieglehalter D. Evaluating medical expert systems: what to test and how? Med Inf (Lond) 1990;15:205–17.Google Scholar
  3. [3]
    Nguyen DT, Diamond LW, Priolet G, Sultan C. A decision support system for diagnostic consultation in laboratory hematology. In: MEDINFO 92. Lun KC, Degoulet P, Piemme TE, Rienhoff O (eds), Amsterdam: North Holland 1992; 591–5.Google Scholar
  4. [4]
    Nguyen DT, Diamond LW, Priolet G, Sultan C. Expert system design in hematology diagnosis. Meth Inform Med 1992;31:82–89.PubMedGoogle Scholar
  5. [5]
    Diamond LW, Mishka VG, Seal AH, Nguyen DT. A clinical database as a component of a diagnostic hematology workstation. In: Proceedings of the Eighteenth Annual Symposium on Computer Applications in Medical Care. J. Am Med Informatics Assoc. Symposium Supplement. 1994:298–302.Google Scholar
  6. [6]
    Barahona P, Durinck J Florin C et al. Knowledge Processing for decision support in the health sector; A perspective for the next decade. In: Barahona P, Christensen JP (eds). Knowledge and decisions in Health Telematics, Amsterdam: IOS Press 1994;3–58.Google Scholar
  7. [7]
    Nolan J, McNair P, Brender J. Factors influencing the transferability of medical decision support systems. Int J Biomed Comput 1991;27:7–26.PubMedGoogle Scholar
  8. [8]
    Talmon JL. Guidelines for the evaluation of medical decision aids. Technical report, SEM Concerted Action, 1991.Google Scholar
  9. [9]
    Rector A. Compositional models of medical concepts: Towards re-usable application-independent medical terminologies. In: Barahona P, Christensen JP (eds). Knowledge and Decisions in Health Telematics, Amsterdam: IOS Press 1994;109–14.Google Scholar
  10. [10]
    Diamond LW, Nguyen DT. Linking an electronic textbook to expert systems in haematology. In: Richards B (ed). Healthcare Computing 1994-Current Perspectives in Healthcare Computing, Weybridge, UK: BJHC Books, 1994;269–79.Google Scholar
  11. [11]
    Diamond LW, Nguyen DT, Andreeff M, Maiese RL, Braylan RC. A knowledge-based system for the interpretation of flow cytometry data in leukemias and lymphomas. Cytometry. 1994;17:266–73.PubMedGoogle Scholar
  12. [12]
    Nguyen DT, Cherubino P, Tamino PB, Diamond LW. Computer-assisted bone marrow interpretation: a pattern approach. In: Reichert A, Sadan BA, Bengtsson S, Bryant J, Piccolo U, eds. Proceedings of MIE 93. London: Freund Publishing House, 1993;119–23.Google Scholar
  13. [13]
    Nguyen DT, Mishka VG, Moskowitz FB, Diamond LW. A multiparameter decision support system for lymph node pathology. In: Barahona P, Veloso M, Bryant J, eds. Proceedings of MIE 94. Lisbon: 1994; 162–7.Google Scholar
  14. [14]
    Engelbrecht R, Fitter M, Rector A. Requirements for a medical workstation using user-centred design. In: Adlassnig K-P, Grabner G, Bengtsson S, Hansen R (eds). Medical Informatics Europe 1991. Lecture Notes in Medical Informatics No. 45. Berlin: Springer-Verlag, 1991;140–4.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • Diamond L. W. 
    • 1
  • Nguyen D. T. 
    • 1
  • Ralph P. 
    • 2
  • Sheridan B. 
    • 3
  • Bak A. 
    • 2
  • Kessler C. 
    • 4
  • Muncer D. 
    • 4
  1. 1.Pathology InstituteUniversity of CologneGermany
  2. 2.MDS LaboratoriesEtobicokeCanada
  3. 3.Dept. of Pathology, Sunnybrook Health Science CenterUniversity of TorontoOntarioCanada
  4. 4.Coulter Technology CenterMiamiUSA

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