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Nonequilibrium Fluctuations of a Single Biomolecule

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Controlled Nanoscale Motion

Part of the book series: Lecture Notes in Physics ((LNP,volume 711))

Abstract

In recent years it has been realized that equilibrium information is subtly encoded in the fluctuations of a microscopic system that is driven away from equilibrium, such as a biomolecule stretched irreversibly using optical tweezers. The key to decoding this information resides in the external work, W, performed on the system. I will give a brief summary of three theoretical predictions that relate nonequilibrium statistical fluctuations in W to equilibrium properties of the system, and which remain valid even in the far-from-equilibrium limit.

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Author information

Authors and Affiliations

  1. Theoretical Division, T-13, MS B213, Los Alamos National Laboratory, 87545, LAUR-05-4612, Los Alamos, New Mexico

    C. Jarzynski

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  1. C. Jarzynski
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Editor information

Editors and Affiliations

  1. Physics Department, University of Oregon, 97403-1274, Eugene, OR, USA

    Heiner Linke

  2. Department of Chemistry and Biomedical Sciences, University of Kalmar, SE-39182, Kalmar, Sweden

    Alf Månsson

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Jarzynski, C. (2007). Nonequilibrium Fluctuations of a Single Biomolecule. In: Linke, H., Månsson, A. (eds) Controlled Nanoscale Motion. Lecture Notes in Physics, vol 711. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-49522-3_10

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