Skip to main content

3D Graph Description of the Intracerebral Vasculature from Segmented MRA and Tests of Accuracy by Comparison with X-ray Angiograms

  • Conference paper
  • First Online:

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 1613))

Abstract

This paper describes largely automated methods of creating connected, 3D vascular trees from individual vessels segmented from magnetic resonance angiograms. Vessel segmentation is initiated by user-supplied seed points, with automatic calculation of vessel skeletons as image intensity ridges and automatic estimation of vessel widths via medialness calculations. The tree-creation process employs a variant of the minimum spanning tree algorithm and evaluates image intensities at each proposed connection point. We evaluate the accuracy of nodal connections by registering a 3D vascular tree with 4 digital subtraction angiograms (DSAs) obtained from the same patient, and by asking two neuroradiologists to evaluate each nodal connection on each DSA view. No connection was judged incorrect. The approach permits new, clinically useful visualizations of the intracerebral vasculature.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alperin, N., Levin, D.N., Pelizzari, C.A.: Retrospective registration of x-ray angiograms with MR images by using vessels as intrinsic landmarks. JMRI 4 (1994) 139–144

    Article  Google Scholar 

  2. Aylward, S.R., Pizer, S.M., Bullitt, E., Eberly, D.: Intensity ridge and widths for 3D object segmentation and description. IEEE WMMBIA IEEE 96TB100056 (1996) 131–138

    Google Scholar 

  3. Bullitt, E., Liu, A., Aylward, S.R., Soltys, M., Boxwala, A., Rosenman, J., Pizer, S.: Methods for displaying intracerebral vascular anatomy. Am. J. Neuroradiol. 18 (1997) 417–420

    Google Scholar 

  4. Bullitt, E., Liu, A., Pizer, S.M.: Three dimensional reconstruction of curves from pairs of projection views in the presence of error. I. Algorithms. Med. Phys. 24 (1997) 1671–8

    Google Scholar 

  5. Bullitt, E., Liu, A., Pizer, S.M.: Three dimensional reconstruction of curves from projection views. II. Analysis of error. Med. Phys. 24 (1997) 1679–87

    Google Scholar 

  6. Bullitt, E., Liu, A., Aylward, S., Pizer, S.M.: Reconstruction of the intracerebral vasculature from MRA and a pair of projection views. Lect. Notes Comp. Sci. 1230 (1997) 537–542

    Google Scholar 

  7. Chapman, B.E., Sanderson, A.R., Goodrich, K.C., Alexander, A.L., Blatter, D.D., Parker, D.L.: Observer performance methodologies for evaluating blood vessel visibility in MR angiograms using accurate geometric registration to high resolution x-ray angiograms. MRM 37 (1997) 519–529

    Google Scholar 

  8. Feldmar, J., Malandain, G., Ayache, N., Fernandez-Vidal, S., Maurincomme, E., Trousset, Y.: Matching 3D MR angiography data and 2D X-ray angiograms. Lect. Notes Comp. Sci. 1205 (1997) 129–138

    Article  Google Scholar 

  9. Gerig, G,. Koller, T., Székely, G., Brechbühler, C., Kübler, O.: Symbolic description of 3-D structures applied to cerebral vessel tree obtained from MR angiography volume data. Lect. Notes Comp. Sci. 687 (1993) 94–111

    Article  Google Scholar 

  10. Johnson, N.L., Kotz, S., Kemp, A.W.: Univariate Discrete Distributions. New York, Wiley (1992)

    MATH  Google Scholar 

  11. Liu, A., Bullitt, E., Pizer, S.M.: 3D/2D registration using tubular anatomical structures as a basis. Lect. Notes Comp. Sci, 1496 (1998) 952–963

    Article  Google Scholar 

  12. Michiels, J., Pelgrims, P., Bosmans, H., Vandermeulen, D., Gybels, J., Marchal, G., Suetens, P.: On the problem of geometric distortion in magnetic resonance images for stereotactic neurosurgery. Mag. Res. Imag. 12 (1994) 749–765

    Article  Google Scholar 

  13. Michiels, J., Bosmans, H., Nuttin, B., Knauth, M., Verbeeck, R., Vandermeulen, D,. Wilms, G., Marchal, G., Suetens, P., Gybels, J.: The use of magnetic resonance angiography in stereotactic neurosurgery. J. Neurosurg. 82 (1995) 982–987

    Article  Google Scholar 

  14. Navab, N., Bani-Hashemi, A., Nadar, M.S., Wiesent, K., Durlak, P., Brunner, T., Barth, K., Graumann, R.: 3D reconstruction from projection matrices in a C-arm based 3D angiography system. Lecture Notes in Computer Science 1496 (1998) 119–129

    Google Scholar 

  15. Sato, Y., Nakajima, S., Shiraga, N., Atsumi, H., Yoshida, S., Koller, T., Gerig, G., Kikinis, R.: Three-dimensional multi-scale line filter for segmentation and visualization of curvilinear structures in medical images. Medical Image Analysis 2 (1998) 143–168

    Article  Google Scholar 

  16. StatXact: CYTEL Software Corporation, Cambridge, Mass (1995)

    Google Scholar 

  17. Szekely, G., Koller, T., Kikinis, R., Gerig, G.: Structural description and combined 3D display for superior analysis of cerebral vascularity from MRA. SPIE 2359 (1994) 272–281

    Article  Google Scholar 

  18. Wilson, D., Noble, J.A.: Segmentation of cerebral vessels and aneurysms from MR angiography data. Lect. Notes Comp. Sci. 1230 (1997) 428–433

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Bullitt, E. et al. (1999). 3D Graph Description of the Intracerebral Vasculature from Segmented MRA and Tests of Accuracy by Comparison with X-ray Angiograms. In: Kuba, A., Šáamal, M., Todd-Pokropek, A. (eds) Information Processing in Medical Imaging. IPMI 1999. Lecture Notes in Computer Science, vol 1613. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-48714-X_23

Download citation

  • DOI: https://doi.org/10.1007/3-540-48714-X_23

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66167-2

  • Online ISBN: 978-3-540-48714-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics