Modeling Morphological Changes During Contraction of Muscle Fibres by Active Contours

  • Aleš Klemencic
  • Franjo Pernus
  • Stanislav Kovacic
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 1689)


An active contour model with expansion “balloon” forces was used as a tool to simulate the changes in shape and increase in cross-sectional area, which occur during the contraction of isolated muscle fiber. A polygon, imitating the boundaries of the relaxed muscle fiber cross-section, represented the initial position of the active contour model. This contour was then expanded in order to increase the cross-sectional area and at the same time intrinsic elastic properties smoothed the contour. The process of expansion was terminated, when the area of the inflated contour surpassed the preset value. The equations that we give, lead to a controlled expansion of the active contour model.


Active Contour Active Contour Model Shrinking Effect Circular Contour Step Size Parameter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    L.D. Cohen, “On Active Contour Models and Balloons”, CVGIP: Image Understanding, vol. 53/2, pp. 211–218, March 1991.zbMATHCrossRefGoogle Scholar
  2. 2.
    S.R. Gunn, “Dual Active Contour Models for Image Feature Extraction”, Ph.D. Thesis, Faculty of Engineering and Applied Science, Department of Electronics and Computer Science, University of Southampton, 10th May 1996.Google Scholar
  3. 3.
    H. Honda, “Description of cellular patterns by Dirichlet domains: The two-dimensional case” J Theor Biol 72:523–543, 1978.CrossRefMathSciNetGoogle Scholar
  4. 4.
    M. Kass, A. Witkin, D. Terzopoulus, “Snakes: Active Contour Models”, International Journal of Computer Vision, vol. 1/4, pp. 321–331, 1988.CrossRefGoogle Scholar
  5. 5.
    A. Klemeni, S. Kovai, F. Pernus, “Automated Segmentation of Muscle Fiber Images Using Active Contour Models”, Cytometry 32, pp. 317–326, August 1998.CrossRefGoogle Scholar
  6. 6.
    R.L. Lieber, “Skeletal Muscle Structure and Function: Implications for Rehabilitation and Sports Medicine”, Williams & Wilkins, Baltimore, 1992.Google Scholar
  7. 7.
    I.R. Neering, L.A. Quesenberry, V.A. Morris, S.R. Taylor, “Nonuniform volume changes during muscle contraction”, Biophys. J., vol. 59, pp. 926–932, 1991.CrossRefGoogle Scholar
  8. 8.
    S. Lobregt, M.A. Viergever, “A Discrete Dynamic Contour Model”, IEEE Transactions on Medical Imaging, vol. 14/1, pp. 12–24, 1995.CrossRefGoogle Scholar
  9. 9.
    T. McInerney, D. Terzopoulos, “Deformable models in medical image analysis: A survey”, Medical Image Analysis, vol. 1, pp. 91–108, 1996.CrossRefGoogle Scholar
  10. 10.
    S.R. Taylor, I.R. Neering, L.A. Quesenberry, V.A. Morris, “Volume changes during contraction of isolated frog muscle fibers”, In: Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, (Ed.: G.B. Frank), pp. 91–101, Plenum Press, New York, 1992.Google Scholar
  11. 11.
    K. Trombias, P. Baatsen, J. Schreuder, G.H. Pollac, “Contraction-induced movements of water in single fibers of frog skeletal muscle”, J. of Muscle Research and Cell Motility, vol. 14, pp. 573–584, 1993.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • Aleš Klemencic
    • 1
  • Franjo Pernus
    • 1
  • Stanislav Kovacic
    • 1
  1. 1.Faculty of Electrical EngineeringUniversity of LjubljanaLjubljanaSlovenia

Personalised recommendations