Skip to main content

Extended Bayesian Regression Models: A Symbiotic Application of Belief Networks and Multilayer Perceptrons for the Classification of Ovarian Tumors

  • Conference paper
  • First Online:
Artificial Intelligence in Medicine (AIME 2001)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 2101))

Included in the following conference series:

  • 1045 Accesses

Abstract

We describe a methodology based on a dual Belief Network-Multilayer Perceptron representation to build Bayesian classifiers. This methodology combines efficiently the prior domain knowledge and statistical data. We overview how this Bayesian methodology is able (1) to define constructively a valuable “informative” prior for black-box models, (2) to provide uncertainty information with predictions and (3) to handle missing values based on an auxiliary domain model. We assume that the prior domain model is formalized as a Belief Network (since this representation is a practical solution to acquiring prior domain knowledge) while we use black-box models (such as Multilayer Perceptrons) for learning to utilize the statistical data. In a medical task of predicting the malignancy of ovarian masses we demonstrate these two symbiotic applications of Belief Network models and summarize the practical advantages of the Bayesian approach.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. P. Antal, G. Fannes, S. Van Huffel, B. De Moor, J. Vandewalle, and Dirk Timmerman, Bayesian predictive models for ovarian cancer classiffication: evaluation of logistic regresseion, multi-layer perceptron and belief network models in the bayesian context, Proceedings of the Tenth Belgian-Dutch Conference on Machine Learning, BENELEARN 2000, 2000, pp. 125–132.

    Google Scholar 

  2. P. Antal, G. Fannes, H. Verrelst, B. De Moor, and J. Vandewalle, Incorporation of prior knowledge in black-box models: Comparison of transformation methods from bayesian network to multilayer perceptrons, Workshop on Fusion of Domain Knowledge with Data for Decision Support, 16th UAI Conf., 2000, pp. 42–48.

    Google Scholar 

  3. P. Antal, H. Verrelst, D. Timmerman, Y. Moreau, S. Van Huffel, B. De Moor, and I. Vergote, Bayesian networks in ovarian cancer diagnosis: Potential and limitations, Proc. of the 13th IEEE Symp. on Comp.-Based Med.Sys., 2000, Houston, pp. 103–109.

    Google Scholar 

  4. E. Castillo, J.M. Guttiérrez, and A.S. Hadi, Expert systems and probabilistic network models, Springer, 1997.

    Google Scholar 

  5. J. Cloete and J.M. Zurada, Knowledge-based neurocomputing, MIT Press, 2000.

    Google Scholar 

  6. D.J. Spiegelhalter et al., Bayesian analysis in expert systems, Statistical Science 8 (1993), no. 3, 219–283.

    Article  MATH  MathSciNet  Google Scholar 

  7. D. Timmerman et al., Artificial neural network models for the pre-operative discrimination between malignant and benign adnexal masses, Ultrasound Obstet. Gynecol. 13 (1999), 17–25.

    Article  Google Scholar 

  8. J.A. Hanley et al., The meaning and use of the area under receiver operating characteristic (roc) curve, Radiology 143 (1982), 29–36.

    Google Scholar 

  9. J.M. Bernardo et al., Bayesian theory, Wiley & Sons, 1995.

    Google Scholar 

  10. A. Gelman, J.B. Carlin, H.S. Stern., and D.B. Rubin, Bayesian data analysis, Chapman & Hall, 1995.

    Google Scholar 

  11. M.F. Moller, A scaled conjugate gradient algorithm for fast supervised learning, Neural Networks 6 (1993), 525–533.

    Article  Google Scholar 

  12. P. Müller and R.D. Insua, Issues in bayesian analysis of neural network models, Neural Computation 10 (1998), 571–592.

    Article  Google Scholar 

  13. R.M. Neal, Bayesian learning for neural networks, Springer, 1996.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Antal, P., Fannes, G., De Moor, B., Vandewalle, J., Moreau, Y., Timmerman, D. (2001). Extended Bayesian Regression Models: A Symbiotic Application of Belief Networks and Multilayer Perceptrons for the Classification of Ovarian Tumors. In: Quaglini, S., Barahona, P., Andreassen, S. (eds) Artificial Intelligence in Medicine. AIME 2001. Lecture Notes in Computer Science(), vol 2101. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-48229-6_26

Download citation

  • DOI: https://doi.org/10.1007/3-540-48229-6_26

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42294-5

  • Online ISBN: 978-3-540-48229-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics