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Exact and Asymptotic Distribution of the Local Score of One i.i.d. Random Sequence

  • Sabine Mercier
  • Dominique Cellier
  • François Charlot
  • Jean-Jacques Daudin
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 2066)

Abstract

We propose two new and complementary methods to assess the statistical significance of high scoring segments, within both long and short sequences. The numerical results show that these methods improve the work of Karlin et al. implemented in BLAST for the comparison of two sequences.

Keywords

local score statistical significance sequence analysis 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • Sabine Mercier
    • 1
  • Dominique Cellier
    • 2
  • François Charlot
    • 2
  • Jean-Jacques Daudin
    • 3
  1. 1.UFR SES, Département Mathématique et InformatiqueUniversité de Toulouse IIFrance
  2. 2.Analyse et Modèles Stochastiques UPRES A 6085Université de RouenFrance
  3. 3.Département OMIP, UMR INAPG-INRA 96021111Institut National Agronomique Paris-GrignonFrance

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