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The Effects of Radiation on the Structural and Mechanical Properties of Medical Polymers

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Radiation Effects on Polymers for Biological Use

Part of the book series: Advances in Polymer Science ((POLYMER,volume 162))

Abstract

Medical polymers undergo changes in both structural and mechanical properties when subjected to ionizing radiation. Certain classes of polymers are susceptible to chain scission mechanisms while others are altered through crosslinking processes. These generalizations are complicated by the atmosphere in which the polymer is exposed to the ionizing treatment. Because these devices must be sterilized prior to implantation their long-term structural evolution owing to the effects of ionizing radiation coupled with environment must be understood. This work summarizes the wide-ranging effects of ionizing radiation on the mechanical and structural properties of medical polymers.

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References

  1. Matthews IP, Gibson C, Samuel AH (1994) Biomaterials 15:191

    CAS  Google Scholar 

  2. Zimmerli W, Woldvogel FA, Vandaux P, Nydegger UE (1982) Curr Prob Surg 146:487

    CAS  Google Scholar 

  3. Shinozaki T, Deane RS, Mazuzan JE, Hamel AJ, Hazelton D (1983) J Am Med Assoc 249:223

    Article  CAS  Google Scholar 

  4. Leake ES, Glristina AG, Wright MJ (1982) J Clin Microbiol 13:320

    Google Scholar 

  5. Stone HH, Fabian TC, Turkeson ML, Jurkiwicz MJ (1981) Ann Surg 193:612

    Article  CAS  Google Scholar 

  6. Goldman M, Pruitt L (1998) J Biomed Matls Res 40:378

    Article  CAS  Google Scholar 

  7. Shalaby S (1993) Radiation effects on Polymers of biomedical significance. In: Reichmanis E, Frnk CW, O’Donnell HO (eds)Irradiation of Polymeric materials. ACS,Washington, p 315

    Google Scholar 

  8. Gaughran ERL, Goudie AJ (eds)(1978) Sterilization of medical products by ionizing radiation. Multisience Publ, Montreal

    Google Scholar 

  9. Harris LE, Skopek AJ (eds)(1985) Sterilization of medical products. Johnson and Johnson, New South Wales

    Google Scholar 

  10. Reichmanis E, Frank CW, O’Donnell HO (eds)(1993) Irradiation of Polymeric materials. ACS, Washington

    Google Scholar 

  11. Clough RL, Shalaby SW (eds)(1991) Radiation effects on Polymers. ACS, Washington

    Google Scholar 

  12. Clegg DW, Collyer (eds)(1991) Irradiation effects on Polymers. Elsevier, London

    Google Scholar 

  13. Dole M (ed) (1972) Radiation chemistry of Macromolecules, vol I. Academic Press, New York

    Google Scholar 

  14. Dole M (ed) (1973) Radiation chemistry of Macromolecules, vol II. Academic Press, New York

    Google Scholar 

  15. Chapiro A (1962) Radiation chemistry of Polymeric systems. Interscience, New York

    Google Scholar 

  16. Charlesby A (1960) Atomic radiation and Polymers. Pergamon Press, London

    Google Scholar 

  17. Singh A, Silverman J (eds)(1992) Radiation processing of Polymers. Hanser, Munich

    Google Scholar 

  18. Parkinson WW (1987) Radiation resistant Polymers in EPST. Oak Ridge National Lab, Oak Ridge

    Google Scholar 

  19. Brynjolfsson A (1974) Sterilization by ionizing radiation: 145. Multiscience, Montreal

    Google Scholar 

  20. Harrod RA (1977) Radiat Phys Chem 9:91

    Article  Google Scholar 

  21. Eymery R (1974) Sterilization by ionizing radiation: 84. Multiscience, Montreal

    Google Scholar 

  22. McLaughlin WL (1978) Conference on national and international standardization of dosimetry. NIST, Gaithersburg

    Google Scholar 

  23. Tomita K, Sugimoto S, (1977) Radiat Phys Chem 9:576

    Google Scholar 

  24. Burton M (1952) Disc Faraday Soc 12:317

    Google Scholar 

  25. Lyons BJ, Fox AS (1968) JPolym Sci C 21:159

    Google Scholar 

  26. Moore PW (1993) In: Frank CW, O’Donnell HO (eds)Irradiation of Polymeric materials, vol 2. ACS, Washington, p 9

    Google Scholar 

  27. Charlesby A (1954) Proc R Soc London A222:542

    CAS  Google Scholar 

  28. Saito O (1959) JPhys Soc Japan 13:798

    Article  Google Scholar 

  29. Saito O (1972) In: Dole M (ed) The Radiation chemistry of Macromolecules, vol 11. Academic Press New York, p 223

    Google Scholar 

  30. Clough RL (1980) J Am Chem Soc 102:5242

    Article  CAS  Google Scholar 

  31. Wasserman H, Murray R (1979) Singlet oxygen. Academic Press, NY

    Google Scholar 

  32. Clough RL, Gillen KT, Quintana CA (1985) JPolym Sci Polym Chem Ed 23:359

    Article  CAS  Google Scholar 

  33. Bowmer T, Cowen L, O’Donnell, Winzor D (1979) J Appl Polym Sci 24:425

    Article  CAS  Google Scholar 

  34. Matsuo H, Dole M (1959) JPhys Chem 63:395

    Google Scholar 

  35. Wundrich K (1973) JPolym Sci Polym Phys Ed 11:1293

    Google Scholar 

  36. Clough RL, Gillen KT, Campan JL, Gaussens G, Schonbacher H, Seguchi T, Wilski H, Machi S (1984) Nucl Safety 25:198

    Google Scholar 

  37. Kusy RP, Turner DT (1971) Macromolecules 4:337

    Article  Google Scholar 

  38. Bhateja SK, Andrews EH, Young RJ (1983) J Polym Sci Polym Phys Ed 21:523

    Article  CAS  Google Scholar 

  39. Charlesby A (1991) In: Clegg DW, Collyer (eds)Irradiation effects on Polymers. Elsevier, London

    Google Scholar 

  40. Ratner B, Hoffman AS, Schoen FJ, Lemons JE (1996) Introduction to Biomaterials science. Academic Press, New York

    Google Scholar 

  41. Park JB (1979) Biomaterials: an introduction. Plenum Press, New York

    Google Scholar 

  42. Keller A (1981) In: Basset DC (ed) Developments in crystalline Polymers. Applied Science, London, p 37

    Google Scholar 

  43. Bhateja SK (1983) J Appl Polym Sci 28:861

    Article  CAS  Google Scholar 

  44. Salovey R, Bassett DC (1964) J Appl Phys 35:3216

    Article  CAS  Google Scholar 

  45. Shinde A, Salovey R (1985) JPolym Sci 23:1681

    CAS  Google Scholar 

  46. Klein PG, Gonzalez-Orozco JA, Ward IM (1991) Polymer 32:10

    Google Scholar 

  47. Chen CJ, Boose DC, Yeh GSY (1991) Colloid Polym Sci 269:469

    Article  CAS  Google Scholar 

  48. Dole M, Milner DC, Williams TF (1958) J Am Chem Soc 80:1580

    Article  CAS  Google Scholar 

  49. Dijkstra DJ, Hoogsteen W, Pennings AJ (1989) Polymer 30:866

    Article  CAS  Google Scholar 

  50. Grobbelaar CJ, Du Plessis TA, Marais F (1978) J Bone Joint Surg 60B:374

    Google Scholar 

  51. Wroblewski BM, Siney PD, Dowson D, Collins SN (1996) J Bone Joint Surg 78B:280

    Google Scholar 

  52. Shen FW, McKellop HA, Salovey R (1995) J Poly Sci Poly Phys 24:1063

    Google Scholar 

  53. Oonishi H (1995) Orthop Surg Trauma 38:1255

    Google Scholar 

  54. McKellop H, Shen FW, Salovey R (1998) Trans Orth Res Soc 23:98

    Google Scholar 

  55. Premnath V, Harris WH, Jasty M, Merrill EW (1996) Biomaterials 17:1741

    Article  CAS  Google Scholar 

  56. Williams D (1978) Stabilization and degradation of Polymers. In: Allara (ed) Advances in chemistry 169:142

    Google Scholar 

  57. Dunn TS, Epperson BJ, Sugg HW, Stannett VT, Williams JL (1979) Radiat Phys Chem 14:625

    Article  CAS  Google Scholar 

  58. Gavrila DE, Gosse B (1994) J Radioanal Nucl Chem 185:311

    Article  CAS  Google Scholar 

  59. Hegazy EA, Seguchi T, Arakawa K, Machi S (1981) J Appl Polym Sci 26:1361

    Article  CAS  Google Scholar 

  60. Pruitt L (2001) Encyclopedia of materials: science and technology. Williams DF (ed) Advances in Polymer science. Elsevier Science Limited, Oxford

    Google Scholar 

  61. Lyons BJ (1995) Radiat Phys Chem 45:159

    Article  CAS  Google Scholar 

  62. Uscold RE (1984) Appl Polym Sci 29:1335

    Article  Google Scholar 

  63. Licht WR, Kline DE (1964) J Polym Sci A 2:4673

    Google Scholar 

  64. Harada K, Kogure O, Murase K (1982) IEEE Trans Electron Dev 29:518

    Article  Google Scholar 

  65. Dickens B, Martin JW, Waksman D (1984) Polymer 25:107

    Article  Google Scholar 

  66. Lyons BJ, Glover LC (1991) Radiat Phys Chem 37:93

    CAS  Google Scholar 

  67. Zamore A (2001) http://www.nasatech.com

  68. Sanford WM, Lilly WB, Moore WC (1996) Trans 42nd Orthop Res Soc 21:23

    Google Scholar 

  69. Choudhury M, Hutchings IM (1997) Wear 203:335

    Article  Google Scholar 

  70. Rimnac CM, Burstein AH, Carr JM (1994) J Appl Biomater 5:17

    Article  Google Scholar 

  71. Pascaud RS, Evans WT, McCulagh PJ, FitzPatrick D (1995) Soc Biomater 18:809

    Google Scholar 

  72. Rimnac CM, Klein RW, Burstein A, Wight TM, Santner T (1994) Trans Orth Res Soc 19:175

    Google Scholar 

  73. Goldman M, Gronsky R, Long GG, Pruitt L (1998) Polymer Degr Stab 62:97

    Article  CAS  Google Scholar 

  74. McCord JM (1983) Surgery 94:412

    CAS  Google Scholar 

  75. Frank MR, Smith JJ, Bacon RC (1964) J Polym Sci 13:535

    Google Scholar 

  76. Kurtz SM, Muratoglu OK, Evans M, Ediden AA (1999) Biomaterials 20:1659

    Article  CAS  Google Scholar 

  77. Kurtz SM, Rimnac CM, Bartel DL (1997) J Orthop Res 15:57

    Article  CAS  Google Scholar 

  78. Besong AA, Hailey JL, Ingham E (1997) Biomed Mater Eng 7:59

    CAS  Google Scholar 

  79. Currier BH, Currier JH, Collier JP, Mayor MB, Scott RD (1997) Clin Orthop 342:111

    Google Scholar 

  80. Sun DC, Stark C, Dumbleton JH (1994) Polymer 35:969

    Article  CAS  Google Scholar 

  81. Sun DC, Smidig G, Stark C, Dumbleton JH (1996) Trans Orthop Res Soc 21:493

    Google Scholar 

  82. Sanford WM, Saum KA (1995) Trans Orthop Res Soc 20:119

    Google Scholar 

  83. Crane D, Kurtz SM, Pruitt L, Edidin AA (1998) Trans Soc Biomater 21:503

    Google Scholar 

  84. Frank MR, Smith JJ, Bacon RC (1954) J Polym Sci 13:535

    Article  Google Scholar 

  85. Bartell DL, Rimnac CM, Wright TM (1991) In: Goldberg VM (ed) Controversies of total knee arthroplasty. Raven Press, New York, p 61

    Google Scholar 

  86. Baker D, Hastings R, Pruitt L (2000) Polymer 41:795

    Article  CAS  Google Scholar 

  87. Jasty M, Bragdon CR, O’Connor DO (1997) Trans Orthop Res Soc 43:785

    Google Scholar 

  88. McKellop H (1996) Gamma radiation crosslinked UHMWPE. Harvard Hip Course, Boston

    Google Scholar 

  89. Oonishi H, Takayama Y, Tsuji E (1992) Rad Phys Chem 39:495

    CAS  Google Scholar 

  90. McKellop H, Shen FW, Salovey R (1998) Trans Orthop Res Soc 23:98

    Google Scholar 

  91. Edidin AA, Jewett CW, Foulds JR, Kurtz SM (1998) Trans Soc Biomater 21:220

    Google Scholar 

  92. Wang A, Polineni VK, Essner A (1997) Trans Soc Biomater 20:394

    Google Scholar 

  93. Oonishi H, Takayama Y, Tsuji E (1992) Radiat Phys Chem 39:495

    CAS  Google Scholar 

  94. Jasty M, Bragdon CR, O’Connor DO (1997) Trans Orthop Res Soc 43:785

    Google Scholar 

  95. Muratoglu OK, Bragdon CR, O’Connor DO (1997) Soc Biomater 20:74

    Google Scholar 

  96. Baker D, Hastings R, Pruitt L (1999) J Biomed Mat Res 46:573

    Article  CAS  Google Scholar 

  97. Baker D, Bellare A, Pruitt L (2001) J Mat Sci Lett

    Google Scholar 

  98. Bartell DL, Bicknell VL, Wright TM (1986) J Bone Jnt Surg 68:1041

    Google Scholar 

  99. Klapperich C, Komvopoulos K, Pruitt L (1999) In: Biomedical materials for drug delivery, medical implants, and tissue engineering, p 331

    Google Scholar 

  100. Klapperich C (2000) Ph D Thesis, UC Berkeley

    Google Scholar 

  101. Davies J, Harris W (1989) Soc Biomat 89

    Google Scholar 

  102. Harper EP, Braden M, Bonfield W, Dingeldein H, Wahlig H (1997) J Mater Sci Mater Med 8:849

    Article  CAS  Google Scholar 

  103. Lewis G, Mladsi S (1998) Bio materials 19:117

    CAS  Google Scholar 

  104. Goldman M, Pelletier B, Muller S, Ries M, Pruitt L (1998) Trans Orthop Res Soc 217

    Google Scholar 

  105. Hertzberg RW (1983) Deformation and fracture mechanics of engineering materials. Wiley, New York

    Google Scholar 

  106. Graham J, Ries M, Pruitt L, Gundiah N (2000) J Arthroplasty 15:1028

    Article  CAS  Google Scholar 

  107. Park JB, Turner RC, Atkins PE (1980) Biomater Med Dev Artif Organs 8:23

    CAS  Google Scholar 

  108. Pelletier B, Hughes K, Gundiah N, Muller S, Pruitt L, Ries M (1999) Trans Orthop Res Soc 513

    Google Scholar 

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Authors and Affiliations

  1. Departments of Mechanical Engineering and Bioengineering, UC Berkeley, Berkeley, CA, 94720, USA

    Lisa A. Pruitt

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  1. Lisa A. Pruitt
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Editors and Affiliations

  1. c/o IGC I, Lab. of Polyelectrolytes and Biomacromolecules, EPFL-Ecublens, 1015, Lausanne, Switzerland

    Henning Kausch

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Pruitt, L.A. (2003). The Effects of Radiation on the Structural and Mechanical Properties of Medical Polymers. In: Kausch, H., et al. Radiation Effects on Polymers for Biological Use. Advances in Polymer Science, vol 162. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45668-6_3

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  • DOI: https://doi.org/10.1007/3-540-45668-6_3

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  • Print ISBN: 978-3-540-44020-8

  • Online ISBN: 978-3-540-45668-1

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