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Radiation Effects on Polymers for Biological Use pp 1–34Cite as

Engineering and Characterization of Polymer Surfaces for Biomedical Applications

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Part of the book series: Advances in Polymer Science ((POLYMER,volume 162))

Abstract

The application of synthetic polymers in the growing field of materials for medical applications is illustrated by examples from recent work at the Materials Institute of the Swiss Federal Institute of Technology in Lausanne. The review highlights the need for functionalization and chemical control of material surfaces at a molecular/functional level. After a brief introduction into the surface chemical analysis tools, i.e., X-ray Photoelectron Spectroscopy (XPS) and Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) combined with contact angle measurements, phosphorylcholine biomimicking polymers as well as immobilization of carbohydrates on polystyrene are presented.

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References

  1. Ratner BD, Chilkoti A, Lopez GP (1990) Plasma deposition and treatment for biomaterial applications. In:d’Agostino R (ed) Plasma deposition, treatment and etching of polymers. Academic Press, San Diego, pp 463–516

    Google Scholar 

  2. Williams DF ( 1992) Biofunctionality and biocompatibility. In:Williams DF (ed) Medical and dental materials. VCH, Weinheim, pp 1–27

    Google Scholar 

  3. Hubbell JA, Langer R (1995) Chem Eng News 73:42–54

    CAS  Google Scholar 

  4. Mathieu HJ (2001) Surf Interface Anal 32:3–9

    Article  CAS  Google Scholar 

  5. Briggs D, Seah MP (1990) (ed) Practical surface analysis, vol I-Auger and X-ray photoelectron spectroscopy, 2nd edn, vol 1. Wiley, Chichester

    Google Scholar 

  6. Briggs D, Seah MP (1992) (ed) Practical surface analysis, vol II-ion and neutral spectroscopy, vol 2. Wiley, Chichester

    Google Scholar 

  7. Mathieu HJ (2001) Elemental analysis by AES, XPS and SIMS. In:Alfassi ZB (ed) Nondestructive elemental analysis. Blackwell Science, Oxford, pp 201–231

    Google Scholar 

  8. ISO (2001) Surface chemical analysis-X-ray photoelectron spectrometers-calibration of energy scales. In:International Standard 15472, 2001

    Google Scholar 

  9. Beamson G, Briggs D (1992) High resolution XPS of organic polymers. The Scienta ESCA300 database, Wiley, Chichester

    Google Scholar 

  10. Powell CJ, Jablonski A (1999) J Phys Chem Ref Data 28:19–62

    Article  CAS  Google Scholar 

  11. Frydman E, Cohen H, Maoz R, Sagiv J (1997) Langmuir 13:5089–5106

    Article  CAS  Google Scholar 

  12. Buchwalter LP, Czornyj G (1990) J Vac Sci Tech A 8:781–784

    Article  CAS  Google Scholar 

  13. Chaney R, Barth G (1987) Fresenius J Anal Chem 326:143

    Google Scholar 

  14. Clark DT, Brennan WJ (1986) J Electron Spectrosc 41:399–410

    Article  CAS  Google Scholar 

  15. Storp S (1985) Spectrochim Acta B 40:745–756

    Article  Google Scholar 

  16. Coullerez G, Chevolot Y Léonard D, Xanthopoulos N, Mathieu HJ (1999) J Surf Anal 5:235–239

    CAS  Google Scholar 

  17. Vickerman JC (ed) (1997) Surface analysis-the principal techniques. Wiley, Chichester

    Google Scholar 

  18. Briggs D (1992) Static SIMS-surface analysis of organic materials. In:Briggs D, Seah MP (eds) Practical surface analysis, vol 2-ion and neutral spectroscopy. Wiley, Chichester, pp 367–423

    Google Scholar 

  19. Benninghoven A, Stapel D, Brox O, Burkhardt H, Crone C, Thiemann M, Arlinghaus HA (1999) Static SIMS with molecular primary ions. In:SIMS XII. Elsevier, Brussels

    Google Scholar 

  20. Stapel D, Thiemann M, Hagenhoff B, Benninghoven A (1999) Secondary ion emission from LB-layers under molecular primary ion bombardment. In:SIMS XII. Elsevier, Brussels

    Google Scholar 

  21. Hagenhoff B, Cobben PL, Bendel C, Niehuis E, Benninghoven A (1997) Polymers under SF5 bombardment-a systematic investigation. In:SIMS XI. Wiley, Orlando, Florida

    Google Scholar 

  22. Justes DR, Harris RD, Stipdonk MJV, Schweikert AE (1997) A comparison of Cs and C60 primary projectiles for the characterization of GaAs and Si surfaces. In:SIMS XI. Wiley, Orlando, Florida

    Google Scholar 

  23. Vickerman JC, Briggs D (eds) (2001) ToF-SIMS: surface analysis by mass spectrometry. IM Publications and Surface Spectra, Chichester

    Google Scholar 

  24. Vickerman JC, Swift AW (1997) Secondary ion mass spectrometry. In:Vickerman JC (ed) Surface analysis-the principal techniques. Wiley, Chichester, pp 135–214

    Google Scholar 

  25. Young T (1805) Philos Trans R Soc London 96:65

    Google Scholar 

  26. Swain PS, Lipowsky R (1998) Langmuir 14:6772–6780

    Article  CAS  Google Scholar 

  27. Garbassi F, Morra M, Occhiello E (eds) (1994) Polymer surfaces from physics to technology. Wiley, Chichester

    Google Scholar 

  28. Good RJ (1993) Contact angle, wetting, and adhesion: a critical review. In:Mittal KL (ed) Contact angle, wettability and adhesion. VSP-Wiley, Weinheim, pp 3–36

    Google Scholar 

  29. Li D (1996) Colloid Surf A 116:1–23

    Article  CAS  Google Scholar 

  30. Zisman WA (1964) Relation of equilibrium contact angle to liquid and solid constitution. In:Fowkes FM (ed) Contact angle, wettability, and adhesion. American Chemical Society, Washington, D.C., pp 1–51

    Google Scholar 

  31. Boksanyi L, Liardon O, Kovats E (1976) Adv Colloid Interface Sci 6:95–137

    Article  CAS  Google Scholar 

  32. Erard J-F, Nagy L, Kovats E (1983) Colloid Surf 9:109–132

    Article  Google Scholar 

  33. Gobet J, Kovats E (1984) Adsorpt Sci Technol 1:111–122

    CAS  Google Scholar 

  34. Korösi G, Kovats E (1981) J Colloid Surf 2:315–355

    Article  Google Scholar 

  35. Riedo F, Czencz M, Liardon O, Kovats E (1978) Helv Chim Acta 61:1912–1941

    Article  CAS  Google Scholar 

  36. de Gennes PG (1985) Rev Mod Phys 57:827–863

    Article  Google Scholar 

  37. Fowkes FM (1964) Contact angle, wettability, and adhesion. Advances in Chemistry Series, vol 43. American Chemical Society

    Google Scholar 

  38. Holloway PJ (1970) Pestic Sci 1:156–163

    Article  CAS  Google Scholar 

  39. Öner D, McCarthy TJ (2000) Langmuir 16:7777–7782

    Article  CAS  Google Scholar 

  40. Youngblood JP, McCarthy TJ (1999) Macromolecules 32:6800–6806

    Article  CAS  Google Scholar 

  41. Walliser A (1992) Caracterisation des interactions liquide-fibres élémentaires par mouillage. Université de Haute Alsace (F), 92-MUHL-0248

    Google Scholar 

  42. Connor M (1995) Consolidation mechanisms and interfacial phenomena in thermoplastic powder impregnated composites. EPFL Thesis No 1413

    Google Scholar 

  43. Ruiz L (1997) Thesis: synthesis and characterisation of phosphorylcholine containing polymers designed to promote specific cell attachment via surface derivatisation. École Polytechnique Fédérale de Lausanne: Lausanne

    Google Scholar 

  44. Marieb EN (1998) Human anatomy and physiology, 4th edn. Addison-Wesley Publishing

    Google Scholar 

  45. Williams DF (1987) Definitions in Biomaterials, vol 4. Progress in biomedical engineering. Elsevier

    Google Scholar 

  46. Kadoma Y, Nakabayashi N, Masuhara E, Yamauchi J (1978) Kobunshi Ronbunshu 35:423–427

    CAS  Google Scholar 

  47. Chapman D (1993) Langmuir 9:39–45

    Article  CAS  Google Scholar 

  48. Hayward JA, Chapman D (1984) Biomaterials 5:135–142

    Article  CAS  Google Scholar 

  49. Ishihara K, Aragaki R, Ueda T, Watenabe A, Nakabayashi N (1990) J Biomed Mater Res 24:1069–1077

    Article  CAS  Google Scholar 

  50. Ishihara K, Aragaki R,Y amazaki JI, Ueda T, Watenabe A, Nakabayashi N (1990) Seitai Zairyo 8:231–236

    CAS  Google Scholar 

  51. Ishihara K, Oshida H, Endo Y, Ueda T, Watenabe A, Nakabayashi N (1992) J Biomed Mater Res 26:1543–1552

    Article  CAS  Google Scholar 

  52. Lelah MD, Cooper SL (1986) Polyurethanes in medicine. CRC Press

    Google Scholar 

  53. Ruiz L, Johnston DS, Makohliso SA, Aebischer P, Mathieu HJ (1995) Biomimetic coatings on silicon wafers: synthesis and characterisation in ECASIA 95 Montreux, Switzerland. Mathieu HJ, Reike B, Briggs D (eds.) Wiley, Chichester

    Google Scholar 

  54. Yung LL, Cooper LS (1998) Biomaterials 19:31

    Article  CAS  Google Scholar 

  55. Baumgartner JN, Yang CZ, Cooper SL (1997) Biomaterials 18:831

    Article  CAS  Google Scholar 

  56. Ruiz L, Fine E, Vörös J, Makohliso SA, Léonard D, Johnston DS, Textor M, Mathieu HJ (1999) JBiomater Sci Polym E 10:931–955

    Google Scholar 

  57. Peyser P (1989) Glass transition temperatures of polymers. In: Brandrup J, Immergut EH (eds) Polymer handbook. Wiley, pp VI 209–277

    Google Scholar 

  58. Ruiz L, Hilborn JG, Léonard D, Mathieu HJ (1998) Biomaterials 19:987–998

    Article  CAS  Google Scholar 

  59. Davies MC, Lynn RAP (1990) Crit Rev Biocompat 5:297–341

    CAS  Google Scholar 

  60. Yianni YP (1992) Biocompatible surfaces based upon biomembrane mimicry In:Quinn PJ, Cherry RJ (eds) Structural and dynamic properties of lipids and membranes. Portland Press, London, UK, pp 187–216

    Google Scholar 

  61. Hearn MJ, Briggs D (1988) Surf Interface Anal 11:198–213

    Article  CAS  Google Scholar 

  62. Phillips MC, Finer EG, Hauser H (1972) Biochim Biophys Acta 290:397–402

    Article  CAS  Google Scholar 

  63. Hauser H (1975) Phospholipid model membranes: demonstration of a structure-activity relationship in chemoreception. Infr Retr Ltd, London

    Google Scholar 

  64. Briggs D, Hearn MJ (1988) Surf Interface Anal 13:647–669

    Google Scholar 

  65. Chilkoti A, Castner DG, Ratner BD, Briggs D (1990) J Vac Sci Technol A8:2274

    Google Scholar 

  66. Tanuma S, Powell CJ, Penn DR (1993) Surf Interface Anal 21:165–176

    Article  Google Scholar 

  67. Seah MP, Dench WA (1979) Surf Interface Anal 1:2–11

    Article  CAS  Google Scholar 

  68. Garbassi F, Morra M, Occhiello E (1994) Surface energetics and contact angle. In:Polymer surfaces from physics to technology. Wiley, Chichester, chap 4, pp 161–219

    Google Scholar 

  69. Holly FJ, Refojo MF (1975) J Biomed Mater Res 9:315–326

    Article  CAS  Google Scholar 

  70. Lavielle L, Schultz J (1985) J Colloid Interface Sci 106:438–445

    Article  CAS  Google Scholar 

  71. Lavielle L, Schultz J,S anfeld A (1985) J Colloid Interface Sci 106:446–451

    Article  CAS  Google Scholar 

  72. Andrade JD (1988) Polymer surface dynamics. Plenum Press, New York London

    Google Scholar 

  73. Ratner BD, Weathersby P, Hoffman AS, Kelly MA, Scharpen LH (1978) J Appl Polym Sci 22:643–664

    Article  CAS  Google Scholar 

  74. Wirpsza Z (1993) Polyurethanes: chemistry, technology and applications. Polymer science series. Ellis Horwood PTR Prentice Hall

    Google Scholar 

  75. Chevolot Y (1999) Thesis: Surface photoimmobilisation of aryl dyazirine containing carbohydrates-tools toward surface glycoengineering. École Polytechnique Fédérale de Lausanne, Lausanne

    Google Scholar 

  76. Lee YC, Lee RT (1995) Acc Chem Res 28:321–327

    Article  CAS  Google Scholar 

  77. Monsigny M (1995) Biofutur 142:27–32

    Article  Google Scholar 

  78. Petrak K (1994) Adv Drug Deliver Rev 13:211–213

    Article  Google Scholar 

  79. Varki A (1995) Glycobiology 3:97–130

    Article  Google Scholar 

  80. Hatanaka K, Takeshige H, Akaike T (1994) Carbohydr Chem 13:603–610

    Article  CAS  Google Scholar 

  81. Hermanson GT, Mallia AK, Smith PK (1992) Immobilized affinity ligand techniques. Academic Press

    Google Scholar 

  82. Kobayashi K, Kobayashi A, Akaike T (1994) Method Enzymol 247:409–419

    Article  CAS  Google Scholar 

  83. Onyiriuka EC (1990) Appl Spectrosc 44:808–811

    Article  CAS  Google Scholar 

  84. Kobyashi K, Akaike T, Usui T (1994) Method Enzymol 242:226–235

    Article  Google Scholar 

  85. Guire PE (1990) Method of improving the biocompatibility of solid surfaces. Pat 4-973-493, Bio-Metric Systems, Inc, US

    Google Scholar 

  86. Guire PE (1990) Biocompatible Coating for Solid Surfaces. Pat 4-979-959, Bio-Metric Systems, Inc, US

    Google Scholar 

  87. Erdtmann M, Keller R, Baumann H (1994) Biomaterials 15:1043–1049

    Article  CAS  Google Scholar 

  88. Anderson AB, Tran TH, Hamilton MJ, Chudzik SJ, Hasting BP, Melchior MJ, Hergen-rother RW (1996) Am J Neuroradiol 17:859–863

    CAS  Google Scholar 

  89. Anderson AB, Enrico LS, Melchior MJ, Pietig JA, Tran LV, Tran TH, Duquette PH (1994) Photochemical immobilization of heparin to reduce thrombogenesis. Tewntieth Annual Meeting of the Society for Biomaterials, Boston, MA, USA

    Google Scholar 

  90. Sigrist H, Collioud A, Clémence J-F, Gao H, Luginbühl R, Sänger M, Sundarababu G (1995) Opt Eng 34:2339–2347

    Article  CAS  Google Scholar 

  91. Gao H, Sanger M, Luginbühl R, Sigrist H (1995) Biosens Biolectron 10:317–328

    Article  CAS  Google Scholar 

  92. Gao H, Luginbühl R, Sigrist H (1997) Sens Actuators B 38/39:38–41

    Article  Google Scholar 

  93. Collioud A, Clémence J-F, Sänger M, Sigrist H (1993) Bioconjugate Chem 4:528–536

    Article  CAS  Google Scholar 

  94. Léonard D, Chevolot Y, Bucher O, Haenni W, Sigrist H, Mathieu HJ (1998) Surf Interface Anal 26:783–792

    Article  Google Scholar 

  95. Chevolot Y, Bucher O, Léonard D, Mathieu HJ, Sigrist H (1999) Bioconjugate Chem 10:169–175

    Article  CAS  Google Scholar 

  96. Léonard D, Chevolot Y, Bucher O, Sigrist H, Mathieu HJ (1998) Surf Interface Anal 26:793–799

    Article  Google Scholar 

  97. Léonard D, Chevolot Y, Heger F, Martins J, Crout DHG, Sigrist H, Mathieu HJ (2001) Surf Interface Anal 2001:457–464

    Article  Google Scholar 

  98. Yamashita K (1989) Method Enzymol 179:331

    Article  CAS  Google Scholar 

  99. Stockert RJ, Morell AG, Ashwell G (1991) 12:441

    Google Scholar 

  100. Baenziger JU, Maynard Y (1980)J Biol Chem 255:4607–4613

    CAS  Google Scholar 

  101. Schwartz AL (1990) Annu Rev Immunol 8:195–229

    Article  CAS  Google Scholar 

  102. Ashwell G, Harford J (1982) Annu Rev Biochem 51:531–554

    Article  CAS  Google Scholar 

  103. Kawasaki T, Ashwell G (1976)J Biol Chem 251:12

    Google Scholar 

  104. Malissard M, Zeng S, Berger EG (1999) Bioconjugate Chem 16:125

    CAS  Google Scholar 

  105. Chevolot Y, Martins J, Milosevic N, Léonard D, Zeng S, Malissard M, Berger EG, Maier P, Mathieu HJ, Crout DHG, Sigrist H (2001) Bioorgan Med Chem 9:2943–2953

    Article  CAS  Google Scholar 

  106. Sigrist H, Chevolot Y, Crout D, Martins J, Mathieu HJ, Lohmann D (2000) European Patent Application 99112422.3-2110

    Google Scholar 

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Authors and Affiliations

  1. Materials Institute, École Polytechnique Fédérale de Lausanne (EPFL), 1015, Lausanne EPFL, Switzerland

    Hans Jörg Mathieu

  2. Laboratoires Goëmar, UMR 1931 CNRS/Laboratoires Goëmar, Station biologique, 29660, Roscoff, France

    Yann Chevolot

  3. Zyomyx Inc., 26101 Research Road, Hayward, CA, 94545, USA

    Laurence Ruiz-Taylor

  4. Analytical Technology, Microanalysis group, GE Plastics Europe, NL-4600 AC, Bergen op Zoom, The Netherlands

    Didier Léonard

Authors
  1. Hans Jörg Mathieu
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  2. Yann Chevolot
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  3. Laurence Ruiz-Taylor
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  4. Didier Léonard
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Editor information

Editors and Affiliations

  1. c/o IGC I, Lab. of Polyelectrolytes and Biomacromolecules, EPFL-Ecublens, 1015, Lausanne, Switzerland

    Henning Kausch

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Mathieu, H.J., Chevolot, Y., Ruiz-Taylor, L., Léonard, D. (2003). Engineering and Characterization of Polymer Surfaces for Biomedical Applications. In: Kausch, H., et al. Radiation Effects on Polymers for Biological Use. Advances in Polymer Science, vol 162. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45668-6_1

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  • DOI: https://doi.org/10.1007/3-540-45668-6_1

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