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Experimental and Computational Modeling of Cardiac Electromechanical Coupling

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Functional Imaging and Modeling of the Heart (FIMH 2001)

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Abstract

Perturbations in ventricular mechanical loading can be arrhythmogenic and have been associated with sudden cardiac death in patients suffering from congestive heart failure, dilated cardiomyopathy, or ventricular volume overload (1–3). Stretch-induced changes in action potential propagation or repolarization could provide a mechanism for mechanically induced arrhythmias. However, there is a paucity of information regarding the effects of altered load on conduction velocity. The few existing reports present an unclear picture; some of the discrepancies may be due to the varying techniques used.

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Author information

Authors and Affiliations

  1. Department of Bioengineering, The Whitaker Institute for Biomedical Engineering, University of California San Diego, La Jolla, California

    Andrew D. McCulloch, Derrick Sung, Mary Ellen Thomas & Anushka Michailova

Authors
  1. Andrew D. McCulloch
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  2. Derrick Sung
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  3. Mary Ellen Thomas
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  4. Anushka Michailova
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Editor information

Editors and Affiliations

  1. Helsinki University of Technology, Institute of Biomedical Engineering, P.O.Box 2200, 02015, Finland

    Toivo Katila  & Jukka Nenonen  & 

  2. bâtiment Blaise Pascal, CREATIS, CNRS, INSA, 20, boulevard Albert Einstein, 69621, Villeurbanne cedex, France

    Isabelle E. Magnin , Patrick Clarysse  & Johan Montagnat ,  & 

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© 2001 Springer-Verlag Berlin Heidelberg

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McCulloch, A.D., Sung, D., Thomas, M.E., Michailova, A. (2001). Experimental and Computational Modeling of Cardiac Electromechanical Coupling. In: Katila, T., Nenonen, J., Magnin, I.E., Clarysse, P., Montagnat, J. (eds) Functional Imaging and Modeling of the Heart. FIMH 2001. Lecture Notes in Computer Science, vol 2230. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45572-8_16

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  • DOI: https://doi.org/10.1007/3-540-45572-8_16

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42861-9

  • Online ISBN: 978-3-540-45572-1

  • eBook Packages: Springer Book Archive

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