Abstract
The aim of the paper is to present the application of fuzzy sets to image processing and analysis of renal biopsies in light and confocal microscopy. Fuzzy segmentation was applied to processing of grey scale images. Colour images were processed by fuzzy-like approach. Segmented glomerular profiles and interstitial fibrosis were then quantitatively assessed. The mean glomerular volume and the degree of fibrosis were estimated in light microscopy. The volume of glomerular mesangium was assessed with a confocal microscope. Concluding, fuzzy processing makes morphometric studies of renal biopsies more practical for clinical diagnosis of diseases.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Jendrysik F., Eichweld H., Graumann R.: Fuzzy Segmentation Method Applied to the Extraction of Kidney Boundaries in Medical Images. Proc. EUFIT’97, Aachen, Spetember 8–11, 1997: 2360–2364
Kaczmarek E: Quantification of three-dimensional vascular patterns in renal glomeruli. Acta Stereol. 1998 Vol. 15/2: 147–152
Kaczmarek E., Becker R. L.: Three-Dimensional Modeling of Renal Glomerular Capillary Networks. Analytical and Quantitative Cytology and Histology. Vol. 19, (1997): 93–101
Kaczmarek E: Visualization and modelling of renal capillaries from confocal images. Med. Biol. Eng. Comput. 1999 Vol. 37: 273–277
Lee C.-Y., Kuo Y.-H., Yu P.-T.: Weighted fuzzy mean filter for image processing. Fuzzy Sets and Systems. 1997 Vol. 89: 157–180
Paparaskevakou H. Et al.: Membranous glomerulonephritis: A morphometric study. Pathology, Research & Practice. 2000 Vol. 196(3): 141–144
Russ J.C., Computer Assisted Microscopy. The Measurement and Analysis of Images. Plenum, New York, third edition, 1992
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2001 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Kaczmarek, E., Wozniak, A., Salwa-Zurawska, W. (2001). Fuzzy Sets Applied to Image Processing and Quantification of Interstitial Fibrosis and Glomerular Size in Computer Assisted Microscopy. In: Crespo, J., Maojo, V., Martin, F. (eds) Medical Data Analysis. ISMDA 2001. Lecture Notes in Computer Science, vol 2199. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45497-7_18
Download citation
DOI: https://doi.org/10.1007/3-540-45497-7_18
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-42734-6
Online ISBN: 978-3-540-45497-7
eBook Packages: Springer Book Archive