Skip to main content

Web-Enabled Knowledge-Based Analysis of Genetic Data

  • Conference paper
  • First Online:
Medical Data Analysis (ISMDA 2001)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2199))

Included in the following conference series:

Abstract

We present a web-based implementation of GenePath, an intelligent assistant tool for data analysis in functional genomics. GenePath considers mutant data and uses expert-defined patterns to find gene-to-gene or gene-to-outcome relations. It presents the results of analysis as genetic networks, wherein a set of genes has various influence on one another and on a biological outcome. In the paper, we particularly focus on its web-based interface and explanation mechanisms.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bratko, I.: Prolog Programming for Artificial Intelligence. 3rd edition. Addison-Wesley (2001)

    Google Scholar 

  2. Flach, P.: Simply Logical: Intelligent Reasoning by Example. John Wiley & Sons (1994)

    Google Scholar 

  3. Hieter, P., Boguski, M.: Related Articles Functional genomics: it’s all how you read it. Science (1997) 278(5338):601–2

    Article  Google Scholar 

  4. Souza, G. M., da Silva, A. M., Kuspa, A.: Starvation promotes dictyostelium development by relieving PufA inhibition of PKA translation through the YakA kinase pathway. Development (1999) 126(14):3263–3274

    Google Scholar 

  5. Souza, G. M., Lu, S., Kuspa, A.: YakA, a protein kinase, required for the transition from growth to development in Dictyostelium. Development (1998) 125(12):2291–2302

    Google Scholar 

  6. Zhang, M. Q.: Large-scale gene expression data analysis: a new challenge to computational biologists. Genome Res (1999) 9:681–688

    Google Scholar 

  7. Zimmer, C.: The slime alternative. Discover (May 1998) 86–93

    Google Scholar 

  8. Zupan, B., Bratko, I., Demšar, J., Beck, J. R., Kuspa, A., Shaulsky, G.: Abductive Inference of Genetic Networks. Proc. Artificial Intelligence in Medicine Europe. Cascais, Portugal (2001)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Juvan, P. et al. (2001). Web-Enabled Knowledge-Based Analysis of Genetic Data. In: Crespo, J., Maojo, V., Martin, F. (eds) Medical Data Analysis. ISMDA 2001. Lecture Notes in Computer Science, vol 2199. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45497-7_17

Download citation

  • DOI: https://doi.org/10.1007/3-540-45497-7_17

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42734-6

  • Online ISBN: 978-3-540-45497-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics