Abstract
The behavior of single molecular motors such as kinesin or myosin V, which move on linear filaments, involves a nontrivial coupling between the bio-chemical motor cycle and the stochastic movement. This coupling can be studied in the framework of nonuniform ratchet models which are characterized by spa-tially localized transition rates between the different internal states of the motor. These models can be classified according to their functional relationships between the motor velocity and the concentration of the fuel molecules. The simplest such relationship applies to two subclasses of models for dimeric kinesin and agrees with experimental observations on this molecular motor.
It is amusing to note that these pumps act as Maxwell’s demons [2] who (or which!) are able to sort two types of molecules into two different compartments.
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Lipowsky, R. (2000). Molecular Motors and Stochastic Models. In: Freund, J.A., Pöschel, T. (eds) Stochastic Processes in Physics, Chemistry, and Biology. Lecture Notes in Physics, vol 557. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45396-2_2
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DOI: https://doi.org/10.1007/3-540-45396-2_2
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