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Perspectives in Liquid Membrane Extraction of Cephalosporin Antibiotics

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History and Trends in Bioprocessing and Biotransformation

Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 75))

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Abstract

In this paper an overview of the developments in liquid membrane extraction of cephalosporin antibiotics has been presented. The principle of reactive extraction via the so-called liquid-liquid ion exchange extraction mechanism can be exploited to develop liquid membrane processes for extraction of cephalosporin antibiotics. The mathematical models that have been used to simulate experimental data have been discussed. Emulsion liquid membrane and supported liquid membrane could provide high extraction flux for cephalosporins, but stability problems need to be fully resolved for process application. Non-dispersive extraction in hollow fiber membrane is likely to offer an attractive alternative in this respect. The applicability of the liquid membrane process has been discussed from process engineering and design considerations.

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References

  1. Martin JF, Liras P ( 1989) Enzymes involved in penicillin, cephalosporin and cephamycin biosynthesis. In: Fiechter A (ed) Adv in Biochem Eng Biotech. Springer, Berlin Heidelberg New York

    Google Scholar 

  2. Newton GGF, Abraham EP (1955) Nature 24:443

    Google Scholar 

  3. Lancini G, Lorenzetti R (1993) Biotechnology of antibiotics and other bioactive microbial metabolites, 2nd edn. Plenum Press, New York

    Google Scholar 

  4. Vandamme EJ (1990) Recent advances in the biotechnology of β-lactam and microbial bioactive peptides. In: Klein Kauf H, Von Dohren H (eds) Biochemistry of peptides antibiotics. Watter De Gruyter, Berlin

    Google Scholar 

  5. Hyun CK, Kim JK, Ruy DDY (1993) Biotech Bioeng 42:800

    Article  CAS  Google Scholar 

  6. Schewale JG, Sivaraman H (1998) Proc Biochem 8X: 148

    Google Scholar 

  7. Leinn JJ (1988) Eur Pat 0,293,218

    Google Scholar 

  8. Aramori I, Fukugawa M, Tsumara M, Iwami M, Ono H, Ishitani Y, Kojo H, Kohsaka M, Ueda Y, Iomanak H (1992) J Ferment Bioeng 73:185

    Article  CAS  Google Scholar 

  9. Abraham EP, Loder HP (1972) In: Flynn HE (ed) Cephalosporins and penicillins: chemistry and biology. Academic Press, New York

    Google Scholar 

  10. Binder R, Brown J, Romanick G (1994) Appl Environ Microbiol 60:1805

    CAS  Google Scholar 

  11. Parmer A, Kumar H, Marwaha SS, Kenedy JF (1998) Crit Rev Biotech 18:1

    Article  Google Scholar 

  12. Ghosh AC, Mathur RK, Dutta NN (1997) Extraction and purification of cephalosporin antibiotics. In: Scheper T (ed) Adv Biochem Eng Biotech 56:111–145

    Google Scholar 

  13. Li NN (1971) Ind Eng Chem (Proc Des Devel) 10:215

    Article  CAS  Google Scholar 

  14. Wald AS, Leysez LJ, Matson LS (1989) Paper presented at the 3rd Annual meeting of the North American Membrane Society, 19 May, Texas, USA

    Google Scholar 

  15. Schugerl K (1994) Solvent extraction in biotechnology: recovery of primary and secondary metabolites, 1st edn. Springer, Berlin Heidelberg New York

    Google Scholar 

  16. Likidis Z, Schugerl K (1987) J Biotechnol 5:293

    Article  CAS  Google Scholar 

  17. Reschke N, Schugerl K (1986) Chem Eng Biochem Eng J 32: B1–B5

    CAS  Google Scholar 

  18. Muller B, Schlichting E, Schugerl K ( 1988) Appl Microbiol. Biotechnol, 27:484

    Google Scholar 

  19. Likidis Z, Schlichting E, Bishoff E, Schugerl K (1989) Biotech Bioeng 33:1385

    Article  CAS  Google Scholar 

  20. Lee KH, Lee WK (1994) Sep Sci. Technol 29:602

    Google Scholar 

  21. Harris TAJ, Khan S, Reuban GB, Shokoya T (1990) In: Pyle DL (ed) Separations for biotechnology. Elsevier, London, pp 172–180

    Google Scholar 

  22. Hano T, Matsumoto M, Ohtake T, Hori F (1992) J Chem Eng Jpn 25:293

    Article  CAS  Google Scholar 

  23. Sahoo GC, Ghosh AC, Dutta NN, Mathur RK (1996) J Membr Sci 112:147

    Article  CAS  Google Scholar 

  24. Sahoo GC, Ghosh AC, Dutta NN (1997) Process Biochem 32:265

    Article  CAS  Google Scholar 

  25. Sahoo GC, Dutta NN (1998) J Membr Sci 145:15

    Article  CAS  Google Scholar 

  26. Sahoo GC, Dass NN, Dutta NN (1999) J Membr Sci 157:251

    Article  CAS  Google Scholar 

  27. Sahoo GC, Borthakur S, Dass NN, Dutta NN (1999) Bioprocess Eng 20:117

    Article  CAS  Google Scholar 

  28. Li NN (1968) US Pat 3,410,794

    Google Scholar 

  29. Ho WSW, Li NN (1992) In: Ho WSW, Sirkar KK (eds) Membrane handbook, 1st edn. Van Nostrand Reinhold, New York

    Google Scholar 

  30. Mutihac L, Mutihac RZ, Nocolace LC, Constantinescu T (1992) Rev Roum Chim 37:91

    CAS  Google Scholar 

  31. Mutihac L, Luca C (1991) Rev Roum Chim 36:85

    CAS  Google Scholar 

  32. Mutihac L, Mutihac R (1992) Acta Chim Hung 129:573

    CAS  Google Scholar 

  33. Lazarova Z, Peeva L (1994) Biotechnol Bioeng 43:907

    Article  CAS  Google Scholar 

  34. Roberts J, Caserio M (1964) Basic principles of organic chemistry, 1st edn. Benjamin Inc, New York, 2:247

    Google Scholar 

  35. Scheper T, Likidis Z, Makryaleas K, Nowottry C, Schugerl K (1987) Enz Microb Technol 9:625

    Article  CAS  Google Scholar 

  36. Boayadzhiev L, Attanassova I (1991) Biotech Bioeng 38:1059

    Article  Google Scholar 

  37. Smith BD (1996) In: Bartsch RA, Way JD (eds) Chemical separation with liquid membrane. ACS Symposium Series: 642. American Chemical Society, Washington, DC, pp 194–205

    Google Scholar 

  38. Smith BD (1996) Supramol Chem 7:55

    Article  CAS  Google Scholar 

  39. Smith BD, Gardiner SJ (1998) Adv Supramol Chem 5:157

    Google Scholar 

  40. Cascaval D, Oniscu C, Cascaval C, Romanic M (1997) Roum Biotechnol Lett 2:407

    CAS  Google Scholar 

  41. Sahoo GC, Dutta NN, Dass NN (2000) Chem Eng Comm (in press)

    Google Scholar 

  42. Habaki H, Isobe S, Ega-Shiva R, Kawasaki J ( 1998) J Chem Eng Jpn 31:47

    Article  CAS  Google Scholar 

  43. Tsikas D, Scheper T, Schugerl K ( 1989) Chem Ing Tech 61:418

    Article  CAS  Google Scholar 

  44. Chan CC, Yang JF (1995) Sep Sci Technol 30(15):3001

    Article  CAS  Google Scholar 

  45. Thien MP, Hatton TA, Wang DIC (1988) Biotechnol Bioeng 32:604

    Article  CAS  Google Scholar 

  46. Reisinger H, Marr R (1993) J Membr Sci 80:85

    Article  CAS  Google Scholar 

  47. Hong S-A, Choi H-J, Nam SW (1992) J Membr Sci 70:225

    Article  CAS  Google Scholar 

  48. Chaudhuri JB, Pyle DL ( 1992) Chem Eng Sci 47:49

    Article  CAS  Google Scholar 

  49. Wildfenur EM (1985) In: Leroith O, Schiloach J, Leaby JT (eds) ACS Symposium Series, ACS, Washington DC, 77:155–174

    Google Scholar 

  50. Hano T, Ohtake T, Matsumoto M, Ogawa SI, Hari F ( 1990) J Chem Eng Jpn 23:772

    Article  CAS  Google Scholar 

  51. Bora MM, Dutta NN, Bhattacharya KG ( 1998) J Chem Eng Data 43:318

    Article  CAS  Google Scholar 

  52. Bora MM, Ghosh AC, Dutta NN, Mathur RK (1997) Canad J Chem Eng 75:520

    Article  CAS  Google Scholar 

  53. Lee SC, Lee WK (1992) J Chem Tech Biotechnol 53:251

    Google Scholar 

  54. Lee KH, Lee SC, Lee WK ( 1994) J Chem Tech Biotech 59:365

    Article  CAS  Google Scholar 

  55. Lee KH, Lee SC, Lee WK (1994) J Chem Tech Biotech 59:371

    Article  CAS  Google Scholar 

  56. Ghosh AC, Borthakur S, Roy MK, Dutta NN (1995) Sep Technol 5:121

    Article  CAS  Google Scholar 

  57. Marchese J, Lopez L, Quin JA (1989) J Chem Tech Biotech 46:149

    Article  CAS  Google Scholar 

  58. Lee JC, Yeh JH, Yang WJ, Kan RC (1993) Biotech Bioeng 42:527

    Article  CAS  Google Scholar 

  59. Lee JC, Yeh JH, Kan RC ( 1994) Biotech Bioeng 43:309

    Article  CAS  Google Scholar 

  60. Tsikas D, Kaltsidon SE, Brunner G (1992) Chem Ing Tech 64:545

    Article  CAS  Google Scholar 

  61. Basu R, Sirkar KK (1991) AIChE J 37:383

    Article  CAS  Google Scholar 

  62. Yang FZ, Rindfleisch D, Scheper T, Schuregl K (1993) 3rd International Conference on Effective Membrane Processes, New Perspectives, Bath, UK, 12–14 May

    Google Scholar 

  63. Prasad R, Sirkar KK ( 1989) J Membr Sci 47:235

    Article  CAS  Google Scholar 

  64. Basu R, Sirkar KK (1992) Solvent Extr Ion Exch 10:119

    Article  CAS  Google Scholar 

  65. Dahuron L, Cussler EL (1988) AIChE J 37:383

    Google Scholar 

  66. Dekker M, Riet K Van’t, Wijmans JMGM, Baltussen JWA (1987) 1st International Congress Membrane and Membrane Processes, Tokyo

    Google Scholar 

  67. Prasad R, Sirkar KK (1990) J Membr Sci 50:153

    Article  CAS  Google Scholar 

  68. Casamatta G, Boyadzhiev L, Angelio H ( 1994) Chem Eng Sci 29:2005

    Article  Google Scholar 

  69. Teramoto M, Matsuyama H, Nakai K, Uesaka T, Ohnishi N (1994) J Membr Sci 91:203

    Article  Google Scholar 

  70. Chaudhuri JB, Pyle DL (1992) Chem Eng Sci 47:41

    Article  CAS  Google Scholar 

  71. Mok YS, Lee WK (1995) Membrane J 5:44

    CAS  Google Scholar 

  72. Calderback PH, Moo-Young MB (1961) Chem Eng Sci 16:39

    Article  Google Scholar 

  73. Wilke CR, Chang P (1955) AIChEJ 264–266

    Google Scholar 

  74. Jefferson TB, Witzell OW, Libbit WL (1958) Ind Eng Chem 50:1518

    Article  Google Scholar 

  75. Gu ZM, Wasan DT, Li NN (1985) Sep Sci Tech 20:599

    Article  CAS  Google Scholar 

  76. Fuji T, Matsumoto K, Watanabe T (1976) Proc Biochem 11:12

    Google Scholar 

  77. Eyal AM, Bressler E ( 1993) Biotech Bioeng 41:287

    Article  CAS  Google Scholar 

  78. Li NN (1973) US Pat. 3,779,907

    Google Scholar 

  79. Friensen DI, Babcock WC, Brose DJ, Chambers AR ( 1991) J Membr Sci 56:127

    Article  Google Scholar 

  80. Bhakta A, Ruckenstein E (1995) Langmuir 11:4642

    Article  CAS  Google Scholar 

  81. Szabo C (1992) Biotechnol Bioeng 4:247

    Article  Google Scholar 

  82. Draxler J, Marr R (1986) Chem Eng Process 20:319

    Article  CAS  Google Scholar 

  83. Li W, Dai X, Shi Y (1992) Proc Int. Solvent Extraction Conf., Kyoto, Japan, Part B, p 1655

    Google Scholar 

  84. Sirkar KK (1991) US Pat. 4,921,612

    Google Scholar 

  85. Sirkar KK (1991) US Pat. 4,997,569

    Google Scholar 

  86. Kemperman AJB, Bergeman D, Van Den BT, Strathmann H (1996) Sep Sci Technol 31(20):2733

    Article  CAS  Google Scholar 

  87. Neplenbrock AM, Bergeman D, Smolders CA (1992) J Membr Sci 67:149

    Article  Google Scholar 

  88. Zhang X-J, Huang P-Y, Chen X-J (1988) Proc First Sino-Jap Symp Liq Membr 24–27 Sept, Chona,pp 83–85

    Google Scholar 

  89. Kato S, Kawasaki J ( 1988) Proc First Sino-Jap Symp Liq Membr 24–27 September, Chona, pp 86–88

    Google Scholar 

  90. Lu G, Lu Q, Li P (1997) J Membr Sci 128:1

    Article  CAS  Google Scholar 

  91. Sun D, Duan X, Yanling X, Zhang LT, Zhou D ( 1996) Harbin Gongye Daxue Xuebao 28:68

    CAS  Google Scholar 

  92. Ghosh AC, Bora MM, Dutta NN (1996) Bioseparation 6:91

    CAS  Google Scholar 

  93. Behr JP (1973) J Am Chem Soc 95:6108

    Article  CAS  Google Scholar 

  94. Lehn JM (1975) J Am Chem Soc 97:2532

    Article  CAS  Google Scholar 

  95. Itosh H, Thien MP, Hatton TA, Wang DIC (1990) Biotech Bioeng 35:853

    Article  Google Scholar 

  96. Boydzhiev L, Atannossova I (1994) Proc Biochem 29:237

    Article  Google Scholar 

  97. Hano T, Matsumoto M, Kawozu T, Ohtake T ( 1995) J Chem Tech Biotech 62:66

    Article  Google Scholar 

  98. Yamaguchi T, Nishimura K, Shinbo T, Seigura M (1985) Chem Lett 10:1552

    Google Scholar 

  99. Bryjak M, Weiczorek P, Kafarski P, Leiczark B ( 1988) J Membr Sci 37:287

    Article  CAS  Google Scholar 

  100. Wieczorek P, Kocorek A, Bryjak M, Kafarski P, Lejczak B ( 1993) J Membr Sci 78:83

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Chemical Engineering Division, Regional Research Laboratory, Jorhat, 785 006, India

    G. C. Sahoo & N. N. Dutta

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  1. G. C. Sahoo
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  2. N. N. Dutta
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N. N. Dutta F. Hammar K. Haralampidis N. G. Karanth A. König S. H. Krishna G. Kunze E. Nagy B. Orlich A. E. Osbourn K. S. M. S. Raghavarao K. Riedel G. C. Sahoo R. Schomäcker N. D. Srinivas M. Trojanowska

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Sahoo, G.C., Dutta, N.N. (2002). Perspectives in Liquid Membrane Extraction of Cephalosporin Antibiotics. In: Dutta, N.N., et al. History and Trends in Bioprocessing and Biotransformation. Advances in Biochemical Engineering/Biotechnology, vol 75. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-44604-4_7

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  • DOI: https://doi.org/10.1007/3-540-44604-4_7

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  • Print ISBN: 978-3-540-42371-3

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