Abstract
The year 2000 will be remembered in history as the year in which the human genome has been sequenced. This marks the end of the pre-genomic era which was characterized by strong world-wide efforts to sequence the human genome and, in fact, ended significantly ahead of schedule. Today, we are at the entry of the probably much longer post-genomic era, which is characterized by the grand quest of making sense of the genomic text. This goal can only be achieved by a concerted effort involving biological experiments and computer analyses. Conquering the computer part is the task of the scientific field of computational biology or bioinformatics. Here we will describe two facets of computational biology. One is that of a discipline shaped by several grand challenge basic research problems. The other is that of a field driven by a strong demand for immediate answers to pressing practical problems in biotechnology, notably in pharmaceutics and medicine.
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Lengauer, T. (2001). Computational Biology at the Beginning of the Post-genomic Era. In: Wilhelm, R. (eds) Informatics. Lecture Notes in Computer Science, vol 2000. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-44577-3_24
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DOI: https://doi.org/10.1007/3-540-44577-3_24
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