Skip to main content

Aralkylamine N-acetyltransferase

  • Chapter
Springer Handbook of Enzymes

Part of the book series: Springer Handbook of Enzymes ((HDBKENZYMES,volume 30))

  • 64 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Namboodiri, M.A.A.; Dubbels, R.; Klein, D.C.: Arylalkylamine N-acetyltransferase from mammalian pineal gland. Methods Enzymol., 142, 583–590 (1987)

    Article  PubMed  CAS  Google Scholar 

  2. Voisin, P.; Namboodiri, M.A.A.; Klein, D.C.: Arylamine N-acetyltransferase and arylalkylamine N-acetyltransferase in the mammalian pineal gland. J. Biol. Chem., 259, 10913–10918 (1984)

    PubMed  CAS  Google Scholar 

  3. Withyachumnarnkul, B.; Pongsa-Asawapaiboon, A.; Poolsanguan, B.: Characteristics of the enzyme N-acetyltransferase in the optic lobe of the giant freshwater prawn, Macrobrrachium rosenbergii. Comp. Biochem. Physiol. B Comp. Biochem., 104, 449–454 (1993)

    Article  Google Scholar 

  4. Namboodiri, M.A.A.; Brownstein, M.J.; Voisin, P.; Weller, J.L.; Klein, D.C.: A simple and rapid method for the purification of ovine pineal arylalkylamine N-acetyltransferase. J. Neurochem., 48, 580–585 (1987)

    Article  PubMed  CAS  Google Scholar 

  5. Ohtomi, M.; Sasaki, M.; Deguchi, T.: Two arylamine N-acetyltransferases from chicken pineal gland as identified by cDNA cloning. Eur. J. Biochem., 185, 253–261 (1989)

    Article  PubMed  CAS  Google Scholar 

  6. Fajardo, N.; Abreu, P.; Alonso, R.: Determination of kinetic properties of serotonin-N-acetyltransferase in bovine pineal gland using HPLC with fluorimetric detection. J. Pineal Res., 13, 80–84 (1992)

    Article  PubMed  CAS  Google Scholar 

  7. Rodriguez-Cabello, J.C.; Agapito, M.T.; Garcia-Herrero, I.; Recio, J.M.: Effects of EGTA and calmodulin, neutral thiol proteinases and protein kinase C inhibitors on loss of chicken pineal serotonin N-acetyltransferase activity. J. Comp. Physiol. B, 159, 583–588 (1989)

    Article  PubMed  CAS  Google Scholar 

  8. Namboodiri, M.A.A.; Brownstein, M.J.; Weller, J.L.; Voisin, P.; Klein, D.C.: Multiple forms of arylalkylamine N-acetyltransferases in the rat pineal gland: purification of one molecular form. J. Pineal Res., 4, 235–246 (1987)

    Article  PubMed  CAS  Google Scholar 

  9. Deguchi, T.: Characteristics of serotonin-acetyl coenzyme A N-acetyltransferase in pineal gland of rat. J. Neurochem., 24, 1083–1085 (1975)

    Article  PubMed  CAS  Google Scholar 

  10. Morrissey, J.J.; Edwards, S.B.; Lovenberg, W.: Comparison of rat pineal gland and rat liver serotonin-N-acetyltransferase. Biochem. Biophys. Res. Commun., 77, 118–123 (1977)

    Article  PubMed  CAS  Google Scholar 

  11. Fleming, J.V.; Barrett, P.; Coon, S.L.; Klein, D.C.; Morgan, P.J.: Ovine arylalkylamine N-acetyltransferase in the pineal and pituitary glands: differences in function and regulation. Endocrinology, 140, 972–978 (1999)

    Article  PubMed  CAS  Google Scholar 

  12. Falcon, J.; Galarneau, K.M.; Weller, J.L.; Ron, B.; Chen, G.; Coon, S.L.; Klein, D.C.: Regulation of arylalkylamine N-acetyltransferase-2 (AANAT2, EC 2.3.1.87) in the fish pineal organ: evidence for a role of proteasomal proteolysis. Endocrinology, 142, 1804–1813 (2001)

    Article  PubMed  CAS  Google Scholar 

  13. Coon, S.L.; Del Olmo, E.; Young, W.S.; Klein, D.C.: Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87). J. Clin. Endocrinol. Metab., 87, 4699–4706 (2002)

    Article  PubMed  CAS  Google Scholar 

  14. Aisien, S.O.; Hellmund, C; Walter, R.D.: Characterization of the arylalkylamine N-acetyltransferase in Onchocerca volvulus. Parasitol. Res., 82, 369–371 (1996)

    Article  PubMed  CAS  Google Scholar 

  15. Obsil, T.; Ghirlando, R.; Klein, D.C.; Ganguly, S.; Dyda, F.: Crystal structure of the 14-3-3ζ:serotonin N-acetyltransferase complex: a role for scaffolding in enzyme regulation. Cell, 105, 257–267 (2001)

    Article  PubMed  CAS  Google Scholar 

  16. Hamada, T.; Ootomi, M.; Horikawa, K.; Niki, T.; Wakamatu, H.; Ishida, N.: The expression of the melatonin synthesis enzyme: arylalkylamine N-acetyltransferase in the suprachiasmatic nucleus of rat brain. Biochem. Biophys. Res. Commun., 258, 772–777 (1999)

    Article  PubMed  CAS  Google Scholar 

  17. Amherd, R.; Hintermann, E.; Walz, D.; Affolter, M.; Meyer, U.A.: Purification, cloning, and characterization of a second arylalkylamine N-acetyltransferase from Drosophila melanogaster. DNA Cell Biol., 19, 697–705 (2000)

    Article  PubMed  CAS  Google Scholar 

  18. Alonso-Gomez, A.L.; Valenciano, A.I.; Alonso-Bedate, M.; Delgado, M.J.: Differential characteristics and regulation of arylamine and arylalkylamine N-acetyltransferases in the frog retina (Rana perezi). Neurochem. Int., 26, 223–231 (1995)

    Article  PubMed  CAS  Google Scholar 

  19. Ivanova, T.N.; Michael Iuvone, P.: Melatonin synthesis in retina: circadian regulation of arylalkylamine N-acetyltransferase activity in cultured photoreceptor cells of embryonic chicken retina. Brain Res., 973, 56–63 (2003)

    Article  PubMed  CAS  Google Scholar 

  20. De Angelis, J.; Gastel, J.; Klein, D.C.; Cole, P.A.: Kinetic analysis of the catalytic mechanism of serotonin N-acetyltransferase (EC 2.3.1.87). J. Biol. Chem., 273, 3045–3050 (1998)

    Article  PubMed  Google Scholar 

  21. Tsuboi, S.; Kotani, Y.; Ogawa, K.i.; Hatanaka, T.; Yatsushiro, S.; Otsuka, M.; Moriyama, Y.: An intramolecular disulfide bridge as a catalytic switch for serotonin N-acetyltransferase. J. Biol. Chem., 277, 44229–44235 (2002)

    Article  PubMed  CAS  Google Scholar 

  22. Scheibner, K.A.; De Angelis, J.; Burley, S.K.; Cole, P.A.: Investigation of the roles of catalytic residues in serotonin N-acetyltransferase. J. Biol. Chem., 277, 18118–18126 (2002)

    Article  PubMed  CAS  Google Scholar 

  23. Khalil, E.M.; De Angelis, J.; Cole, P.A.: Indoleamine analogs as probes of the substrate selectivity and catalytic mechanism of serotonin N-acetyltransferase. J. Biol. Chem., 273, 30321–30327 (1998)

    Article  PubMed  CAS  Google Scholar 

  24. Ferry, G.; Loynel, A.; Kucharczyk, N.; Bertin, S.; Rodriguez, M.; Delagrange, P.; Galizzi, J.P.; Jacoby, E.; Volland, J.P.; Lesieur, D.; Renard, P.; Canet, E.; Fauchere, J.L.; Boutin, J.A.: Substrate specificity and inhibition studies of human serotonin N-acetyltransferase. J. Biol. Chem., 275, 8794–8805 (2000)

    Article  PubMed  CAS  Google Scholar 

  25. Ichihara, N.; Okada, M.; Takeda, M.: Characterization and purification of polymorphic arylalkylamine N-acetyltransferase from the American cockroach, Periplaneta americana. Insect Biochem. Mol. Biol., 32, 15–22 (2001)

    Article  PubMed  CAS  Google Scholar 

  26. Ichihara, N.; Okada, M.; Nakagawa, H.; Takeda, M.: Purification and characterization of arylalkylamine N-acetyltransferase from cockroach testicular organs. Insect Biochem. Mol. Biol., 27, 241–246 (1997)

    Article  PubMed  CAS  Google Scholar 

Download references

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

(2006). Aralkylamine N-acetyltransferase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Springer Handbook of Enzymes. Springer Handbook of Enzymes, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-37717-4_28

Download citation

Publish with us

Policies and ethics