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Isothermal titration calorimetry and fluorescence spectroscopy studies of the interactions between surfactants and a phosphorylcholine-based polybetaine

  • Kazuyuki Miyazawa
  • Francoise M. Winnik
Conference paper
Part of the Progress in Colloid and Polymer Science book series (PROGCOLLOID, volume 122)

Abstract

The interactions between a polybetaine and anionic, cationic, zwitterionic and neutral surfactants were studied by a fluorescence experiment with pyrene as a probe, isothermal titration calorimetry, and 1H NMR spectroscopy. The polybetaine was a phosphorylcholine-based polymer (PNIPAM-PC) consisting of equimolar amounts of N-isopro- pylacrylamide and N-phosphoryl- choline-N′-ethylenedioxybis (ethyl)acrylamide. Strong association took place between PNIPAM-PC and the anionic surfactants sodium n-dodecyl sulfate (SDS) and sodium n-hexadecyl sulfate (SHS) via a cooperative mechanism driven by electrostatic interactions between the surfactant headgroup and the trimethylammonium group of the PC moiety linked to the polymer. The onset of binding between PNIPAM-PC and SDS or SHS takes place for surfactant concentrations of 2.0 and 0.028 mmo11-1, respectively, which are lower than their respective critical micelle concentrations (8.3 and 0.058 mmo11-1). No interactions were detected between PNIPAM-PC and zwitterionic surfactants bearing either a phosphoryl-choline headgroup (n-hexadecanoyl lysophosphocholine) or a dimethyl-3-ammonio-1-propanesulfonate group, cationic surfactants bearing a trimethylammonium headgroup, or neutral surfactants bearing a hepta(ethyleneglycol) headgroup. The mechanism of binding is discussed in terms of surfactant charge and chain length and is compared to the association of surfactants to polyampholytes and polyelectrolytes.

Keywords

Polymer—surfactant interactions Thermodynamics of micellization Electrostatic binding Pyrene fluorescence Microcalorimetry 

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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • Kazuyuki Miyazawa
    • 1
    • 2
  • Francoise M. Winnik
    • 1
  1. 1.Department of Chemistry and Faculty of PharmacyUniversité de MontréalMontréalCanada
  2. 2.Shiseido Basic Research CenterYokohamaJapan

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