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Central Nervous System Tumors

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References

  • American Cancer Society (2005) Cancer facts and figures 2005. American Cancer Society, Atlanta, Georgia

    Google Scholar 

  • Babiloni F, Mattia D, Babiloni C et al (2004) Multimodal integration of EEG, MEG and fMRI data for the solution of the neuroimage puzzle. Magn Reson Imaging 22:1471–1476

    PubMed  Google Scholar 

  • Barnes D, Egan G, O’Keefe G et al (1997) Characterization of dynamic 3-D PET imaging for functional brain mapping. IEEE Trans Med Imaging 16:261–269

    PubMed  CAS  Google Scholar 

  • Barnholtz-Sloan JS, Sloan AE, Davis FG et al (2004) Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System. J Clin Oncol 22:2865–2872

    PubMed  Google Scholar 

  • Bell BA, Smith MA, Kean DM et al (1987) Brain water measured by magnetic resonance imaging. Correlation with direct estimation and changes after mannitol and dexamethasone. Lancet 1:66–69

    PubMed  CAS  Google Scholar 

  • Bilsky M, Posner JB (1993) Intensive and postoperative care of intracranial tumors. In: Ropper AH (ed) Neurological and neurosurgical intensive care. Raven Press, New York, pp 309–329

    Google Scholar 

  • Bilsky MH, Lis E, Raizer J et al (1999) The diagnosis and treatment of metastatic spinal tumor. Oncologist 4:459–469

    PubMed  CAS  Google Scholar 

  • Brodmann K (1908a) Beiträge zur histologischen Lokalisation der Grosshirnrinde. VI. Die Cortexgliederung des Menschen. J Psychol Neurol 10:287–334

    Google Scholar 

  • Brodmann K (1908b) Beiträge zur histologischen Lokalisation der Grosshirnrinde. VI. Die Cortexgliederung des Menschen. J Psychol Neurol 10:231–246

    Google Scholar 

  • Brown PD, Buckner JC, O’Fallon JR et al (2004) Adult patients with supratentorial pilocytic astrocytomas: a prospective multicenter clinical trial. Int J Radiat Oncol Biol Phys 58:1153–1160

    PubMed  Google Scholar 

  • Byrne TN (1992) Spinal cord compression from epidural metastases. N Engl J Med 327:614–619

    PubMed  CAS  Google Scholar 

  • Carson PL, Giger M, Welch MJ et al (2003) Biomedical imaging research opportunities workshop: report and recommendations. Radiology 229:328–339

    PubMed  Google Scholar 

  • CBTRUS (2004) Statistical Report: Primary Brain Tumors in the United States, 1997—2001 Years Data Collected. Central Brain Tumor Registry United States

    Google Scholar 

  • Chang EL, Yi W, Allen PK et al (2003) Hypofractionated radiotherapy for elderly or younger low-performance status glioblastoma patients: outcome and prognostic factors. Int J Radiat Oncol Biol Phys 56:519–528

    PubMed  Google Scholar 

  • Choi SJ, Kim JS, Kim JH et al (2005) [(18)F]3’-deoxy-3’-fluorothymidine PET for the diagnosis and grading of brain tumors. Eur J Nucl Med Mol Imaging (in press)

    Google Scholar 

  • Cohen L, Creditor M (1981) An iso-effect table for radiation tolerance of the human spinal cord. Int J Radiat Oncol Biol Phys 7:961–966

    PubMed  CAS  Google Scholar 

  • Condra KS, Buatti JM, Mendenhall WM et al (1997) Benign meningiomas: primary treatment selection affects survival. Int J Radiat Oncol Biol Phys 39:427–436

    PubMed  CAS  Google Scholar 

  • Connoly ES (1982) Spinal cord tumors in adults. In: Winn RH (ed) Youmans’ neurological surgery. Saunders, Philadelphia, p 3196

    Google Scholar 

  • Daumas-Duport C, Scheithauer B, O’Fallon J et al (1988) Grading of astrocytomas. A simple and reproducible method. Cancer 62:2152–2165

    PubMed  CAS  Google Scholar 

  • Deye J, Abrams J, Coleman N (2005) The National Cancer Institute Guidelines for the use of intensity-modulated radiation therapy in clinical trials. DCTD, NCI. 1-14-2005. http://www3.cancer.gov/rrp/imrt2004.pdf

    Google Scholar 

  • Emami B, Lyman J, Brown A et al (1991) Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21:109–122

    PubMed  CAS  Google Scholar 

  • Epilepsy Foundation of America (1993) Treatment of convulsive status epilepticus. Recommendations of the Epilepsy Foundation of America’s Working Group on Status Epilepticus. JAMA 270:854–859

    Google Scholar 

  • Ferlay J, Bray F, Pisani P, Parkin DM (2001) GLOBOCAN 2002: cancer incidence, mortality and prevalence worldwide, version 1.0. IARC CancerBase 5. IARC, Lyon

    Google Scholar 

  • Forsyth PA, Weaver S, Fulton D et al (2003) Prophylactic anticonvulsants in patients with brain tumour. Can J Neurol Sci 30:106–112

    PubMed  Google Scholar 

  • French L (1966) The use of steroids in the treatment of cerebral edema. Bull NY Acad Med 42:301–311

    Google Scholar 

  • Fuller DB, Bloom JG (1988) Radiotherapy for chordoma. Int J Radiat Oncol Biol Phys 15:331–339

    PubMed  CAS  Google Scholar 

  • Gaspar L, Scott C, Rotman M et al (1997) Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys 37:745–751

    PubMed  CAS  Google Scholar 

  • Gaspar L, Scott C, Murray K et al (2000) Validation of the RTOG recursive partitioning analysis (RPA) classification for brain metastases. Int J Radiat Oncol Biol Phys 47:1001–1006

    PubMed  CAS  Google Scholar 

  • Gerszten PC, Welch WC (2000) Current surgical management of metastatic spinal disease. Oncology (Huntingt) 14:1013–1024

    CAS  Google Scholar 

  • Gilbert RW, Kim JH, Posner JB (1978) Epidural spinal cord compression from metastatic tumor: diagnosis and treatment. Ann Neurol 3:40–51

    PubMed  CAS  Google Scholar 

  • Glantz MJ, Cole BF, Friedberg MH et al (1996) A randomized, blinded, placebo-controlled trial of divalproex sodium prophylaxis in adults with newly diagnosed brain tumors. Neurology 46:985–991

    PubMed  CAS  Google Scholar 

  • Goldsmith BJ, Wara WM, Wilson CB et al (1994) Postoperative irradiation for subtotally resected meningiomas. A retrospective analysis of 140 patients treated from 1967 to 1990. J Neurosurg 80:195–201

    PubMed  CAS  Google Scholar 

  • Greenberg HS, Kim JH, Posner JB (1980) Epidural spinal cord compression from metastatic tumor: results with a new treatment protocol. Ann Neurol 8:361–366

    PubMed  CAS  Google Scholar 

  • Gripp S, Kambergs J, Wittkamp M et al (2004) Coverage of anterior fossa in whole-brain irradiation. Int J Radiat Oncol Biol Phys 59:515–520

    PubMed  Google Scholar 

  • Hazuka MB, Burleson WD, Stroud DN et al (1993) Multiple brain metastases are associated with poor survival in patients treated with surgery and radiotherapy. J Clin Oncol 11:369–373

    PubMed  CAS  Google Scholar 

  • Healey JH, Brown HK (2000) Complications of bone metastases: surgical management. Cancer 88:2940–2951

    PubMed  CAS  Google Scholar 

  • Heimdal K, Hirschberg H, Slettebo H et al (1992) High incidence of serious side effects of high-dose dexamethasone treatment in patients with epidural spinal cord compression. J Neurooncol 12:141–144

    PubMed  CAS  Google Scholar 

  • Helweg-Larsen S, Sorensen PS, Kreiner S (2000) Prognostic factors in metastatic spinal cord compression: a prospective study using multivariate analysis of variables influencing survival and gait function in 153 patients. Int J Radiat Oncol Biol Phys 46:1163–1169

    PubMed  CAS  Google Scholar 

  • Hoskin PJ, Grover A, Bhana R (2003) Metastatic spinal cord compression: radiotherapy outcome and dose fractionation. Radiother Oncol 68:175–180

    PubMed  Google Scholar 

  • Huang E, Teh BS, Strother DR et al (2002) Intensity-modulated radiation therapy for pediatric medulloblastoma: early report on the reduction of ototoxicity. Int J Radiat Oncol Biol Phys 52:599–605

    PubMed  Google Scholar 

  • Huntington HW, Kernohan JW, Stapley LA (1965) Tumors of the central nervous system. Ariz Med 22:683–686

    PubMed  CAS  Google Scholar 

  • Husband DJ, Grant KA, Romaniuk CS (2001) MRI in the diagnosis and treatment of suspected malignant spinal cord compression. Br J Radiol 74:15–23

    PubMed  CAS  Google Scholar 

  • International Agency for Research on Cancer (2000) World Health Organization classification of tumours: pathology and genetics. Tumours of the nervous system, 2nd edn. Oxford Univ Press, Lyon

    Google Scholar 

  • International Commission on Radiation Units and Measurements I (1993) ICRU report 50, prescribing, recording, and reporting photon beam therapy. Nuclear Technology Publishing, Bethesda, MD, USA

    Google Scholar 

  • International Commission on Radiation Units and Measurements I (1999) ICRU report 62: prescribing, recording and reporting photon beam therapy (supplement to ICRU report 50). Nuclear Technology Publishing, Bethesda, MD, USA

    Google Scholar 

  • Jankovic M, Brouwers P, Valsecchi MG, Van Veldhuizen A, Huisman J, Kamphuis R et al. (1994) Association of 1800 cGy cranial irradiation with intellectual function in children with acute lymphoblastic leukaemia. ISPACC. International Study Group on Psychosocial Aspects of Childhood Cancer. Lancet 344:224–227

    PubMed  CAS  Google Scholar 

  • Jasper KR, Hummel SM, Laramore GE (2004) 3D naming system. Med Dosim 29:97–103

    PubMed  Google Scholar 

  • Jeremic B, Djuric L, Mijatovic L (1991) Incidence of radiation myelitis of the cervical spinal cord at doses of 5500 cGy or greater. Cancer 68:2138–2141

    PubMed  CAS  Google Scholar 

  • Kalkanis SN, Eskandar EN, Carter BS et al (2003) Microvascular decompression surgery in the United States, 1996 to 2000: mortality rates, morbidity rates, and the effects of hospital and surgeon volumes. Neurosurgery 52:1251–1261

    PubMed  Google Scholar 

  • Karim AB, Maat B, Hatlevoll R et al (1996) A randomized trial on dose-response in radiation therapy of low-grade cerebral glioma: European Organization for Research and Treatment of Cancer (EORTC) Study 22844. Int J Radiat Oncol Biol Phys 36:549–556

    PubMed  CAS  Google Scholar 

  • Karim AB, Afra D, Cornu P et al (2002) Randomized trial on the efficacy of radiotherapy for cerebral low-grade glioma in the adult: European Organization for Research and Treatment of Cancer Study 22845 with the Medical Research Council study BRO4: an interim analysis. Int J Radiat Oncol Biol Phys 52:316–324

    PubMed  Google Scholar 

  • Loblaw DA, Laperriere NJ (1998) Emergency treatment of malignant extradural spinal cord compression: an evidence-based guideline. J Clin Oncol 16:1613–1624

    PubMed  CAS  Google Scholar 

  • Loblaw DA, Laperriere NJ, Mackillop WJ (2003) A population-based study of malignant spinal cord compression in Ontario. Clin Oncol (R Coll Radiol) 15:211–217

    CAS  Google Scholar 

  • Long DM, Hartmann JF, French LA (1966) The response of experimental cerebral edema to glucosteroid administration. J Neurosurg 24:843–854

    PubMed  CAS  Google Scholar 

  • Macbeth FR, Wheldon TE, Girling DJ et al (1996) Radiation myelopathy: estimates of risk in 1048 patients in three randomized trials of palliative radiotherapy for non-small cell lung cancer. The Medical Research Council Lung Cancer Working Party. Clin Oncol (R Coll Radiol) 8:176–181

    CAS  Google Scholar 

  • Maranzano E, Latini P (1995) Effectiveness of radiation therapy without surgery in metastatic spinal cord compression: final results from a prospective trial. Int J Radiat Oncol Biol Phys 32:959–967

    PubMed  CAS  Google Scholar 

  • Maranzano E, Latini P, Checcaglini F et al (1992) Radiation therapy of spinal cord compression caused by breast cancer: report of a prospective trial. Int J Radiat Oncol Biol Phys 24:301–306

    PubMed  CAS  Google Scholar 

  • Maranzano E, Latini P, Beneventi S et al (1996) Radiotherapy without steroids in selected metastatic spinal cord compression patients. A phase II trial. Am J Clin Oncol 19:179–183

    PubMed  CAS  Google Scholar 

  • Maranzano E, Latini P, Perrucci E et al (1997) Short-course radiotherapy (8 Gy x 2) in metastatic spinal cord compression: an effective and feasible treatment. Int J Radiat Oncol Biol Phys 38:1037–1044

    PubMed  CAS  Google Scholar 

  • Maranzano E, Frattegiani A, Rossi R, Bagnoli R, Mignogna M, Bellavista R, Perrucci E, Lupattelli M, Ponticelli P, Latini P (2002) Randomized trial of two different hypofractionated radiotherapy (RT) schedules (8 Gyx2 vs 5 Gyx3; 3 Gyx5) in metastatic spinal cord compression (MSCC) [abstract]. Radiother Oncol 64:82–83

    Google Scholar 

  • Marcus RB Jr, Million RR (1990) The incidence of myelitis after irradiation of the cervical spinal cord. Int J Radiat Oncol Biol Phys 19:3–8

    PubMed  Google Scholar 

  • McAleese JJ, Stenning SP, Ashley S et al (2003) Hypofractionated radiotherapy for poor prognosis malignant glioma: matched pair survival analysis with MRC controls. Radiother Oncol 67:177–182

    PubMed  CAS  Google Scholar 

  • McCunniff AJ, Liang MJ (1989) Radiation tolerance of the cervical spinal cord. Int J Radiat Oncol Biol Phys 16:675–678

    PubMed  CAS  Google Scholar 

  • McKnight TR, dem Bussche MH, Vigneron DB et al (2002) Histopathological validation of a three-dimensional magnetic resonance spectroscopy index as a predictor of tumor presence. J Neurosurg 97:794–802

    PubMed  Google Scholar 

  • Michalski JM (1998) Spinal canal. In: Leibel SA, Phillips TL (eds) Textbook of radiation oncology. Saunders, Philadelphia, pp 860–875

    Google Scholar 

  • Miller AD, Leslie RA (1994) The area postrema and vomiting. Frontiers Neuroendocrinol 15:301–320

    CAS  Google Scholar 

  • Minehan KJ, Shaw EG, Scheithauer BW et al (1995) Spinal cord astrocytoma: pathological and treatment considerations. J Neurosurg 83:590–595

    PubMed  CAS  Google Scholar 

  • Mintz AH, Kestle J, Rathbone MP et al (1996) A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis. Cancer 78:1470–1476

    PubMed  CAS  Google Scholar 

  • Morris D, Bourland J, Rosenman J et al (2001) Three-dimensional conformal radiation treatment planning and delivery for low-and intermediate-grade gliomas. Semin Radiat Oncol 11:124–137

    PubMed  CAS  Google Scholar 

  • Munley MT, Kearns WT, Hinson WH et al (2002) Bioanatomic IMRT treatment planning with dose function histograms. Int J Radiat Oncol Biol Phys 54:126–126

    Google Scholar 

  • Nieder C, Milas L, Ang KK (2000) Tissue tolerance to reirradiation. Semin Radiat Oncol 10:200–209

    PubMed  CAS  Google Scholar 

  • Niemierko A (1997) Reporting and analyzing dose distributions: a concept of equivalent uniform dose. Med Phys 24:103–110

    PubMed  CAS  Google Scholar 

  • Niewald M, Feldmann U, Feiden W et al (1998) Multivariate logistic analysis of dose-effect relationship and latency of radiomyelopathy after hyperfractionated and conventionally fractionated radiotherapy in animal experiments. Int J Radiat Oncol Biol Phys 41:681–688

    PubMed  CAS  Google Scholar 

  • Nuutinen J, Sonninen P, Lehikoinen P et al (2000) Radiotherapy treatment planning and long-term follow-up with [C-11]methionine pet in patients with low-grade astrocytoma. Int J Radiat Oncol Biol Phys 48:43–52

    PubMed  CAS  Google Scholar 

  • O’Rourke T, George CB, Redmond J III et al (1986) Spinal computed tomography and computed tomographic metrizamide myelography in the early diagnosis of metastatic disease. J Clin Oncol 4:576–583

    PubMed  CAS  Google Scholar 

  • Patchell RA (2003) The management of brain metastases. Cancer Treat Rev 29:533–540

    PubMed  Google Scholar 

  • Patchell RA, Tibbs PA, Walsh JW et al (1990) A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 322:494–500

    PubMed  CAS  Google Scholar 

  • Patchell RA, Tibbs PA, Regine WF et al (2005) Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomized trial. Lancet 366:643–648

    PubMed  Google Scholar 

  • Percy AK, Elveback LR, Okazaki H et al (1972) Neoplasms of the central nervous system. Epidemiologic considerations. Neurology 22:40–48

    PubMed  CAS  Google Scholar 

  • Perry A, Scheithauer BW, Stafford SL et al (1999) “Malignancy” in meningiomas: a clinicopathologic study of 116 patients, with grading implications. Cancer 85:2046–2056

    PubMed  CAS  Google Scholar 

  • Phillips C, Guiney M, Smith J et al (2003) A randomized trial comparing 35 Gy in ten fractions with 60 Gy in 30 fractions of cerebral irradiation for glioblastoma multiforme and older patients with anaplastic astrocytoma. Radiother Oncol 68:23–26

    PubMed  Google Scholar 

  • Pieters RS, O’Farrell D, Fullerton B (1996) Cauda Equina tolerance to radiation therapy [abstract]. Int J Radiat Oncol Biol Phys 36:359

    Google Scholar 

  • Pigott KH, Baddeley H, Maher EJ (1994) Pattern of disease in spinal cord compression on MRI scan and implications for treatment. Clin Oncol (R Coll Radiol) 6:7–10

    CAS  Google Scholar 

  • Pirzkall A, Larson DA, McKnight TR et al (2000) MR-Spectroscopy results in improved target delineation for high-grade gliomas. Int J Radiat Oncol Biol Phys 48:115–115

    Google Scholar 

  • Prados MD, Seiferheld W, Sandler HM et al (2004) Phase III randomized study of radiotherapy plus procarbazine, lomustine, and vincristine with or without BUdR for treatment of anaplastic astrocytoma: final report of RTOG 9404. Int J Radiat Oncol Biol Phys 58:1147–1152

    PubMed  CAS  Google Scholar 

  • Preston-Martin S (1990) Descriptive epidemiology of primary tumors of the spinal cord and spinal meninges in Los Angeles County, 1972—1985. Neuroepidemiology 9:106–111

    PubMed  CAS  Google Scholar 

  • Quinn JA and DeAngelis LM (2000) Neurologic emergencies in the cancer patient. Semin Oncol 27:311–321

    PubMed  CAS  Google Scholar 

  • Rades D, Karstens JH (2002) A comparison of two different radiation schedules for metastatic spinal cord compression considering a new prognostic factor. Strahlenther Onkol 178:556–561

    PubMed  Google Scholar 

  • Rades D, Karstens JH, Alberti W (2002) Role of radiotherapy in the treatment of motor dysfunction due to metastatic spinal cord compression: comparison of three different fractionation schedules. Int J Radiat Oncol Biol Phys 54:1160–1164

    PubMed  Google Scholar 

  • Rades D, Bajrovic A, Alberti W et al (2003a) Is there a doseeffect relationship for the treatment of symptomatic vertebral hemangioma? Int J Radiat Oncol Biol Phys 55:178–181

    PubMed  Google Scholar 

  • Rades D, Fehlauer F, Schild S et al (2003b) Treatment for central neurocytoma: a meta-analysis based on the data of 358 patients. Strahlenther Onkol 179:213–218

    PubMed  Google Scholar 

  • Rades D, Fehlauer F, Hartmann A et al (2004) Reducing the overall treatment time for radiotherapy of metastatic spinal cord compression (MSCC): 3-year results of a prospective observational multi-center study. J Neurooncol 70:77–82

    PubMed  Google Scholar 

  • Rades D, Fehlauer F, Lamszus K et al (2005) Well-differentiated neurocytoma: what is the best available treatment? Neuro Oncol 7:77–83

    PubMed  Google Scholar 

  • Ricci PE, Dungan DH (2001) Imaging of low-and intermediate-grade gliomas. Semin Radiat Oncol 11:103–112

    PubMed  CAS  Google Scholar 

  • Roa W, Brasher PM, Bauman G et al (2004) Abbreviated course of radiation therapy in older patients with glioblastoma multiforme: a prospective randomized clinical trial. J Clin Oncol 22:1583–1588

    PubMed  CAS  Google Scholar 

  • Ruff RL, Lanska DJ (1989) Epidural metastases in prospectively evaluated veterans with cancer and back pain. Cancer 63:2234–2241

    PubMed  CAS  Google Scholar 

  • Sanders KE, Ha CS, Cortes-Franco JE et al (2004) The role of craniospinal irradiation in adults with a central nervous system recurrence of leukemia. Cancer 100:2176–2180

    PubMed  Google Scholar 

  • Sarin R, Murthy V (2003) Medical decompressive therapy for primary and metastatic intracranial tumours. Lancet Neurol 2:357–365

    PubMed  CAS  Google Scholar 

  • Sasanelli F, Beghi E, Kurland LT (1983) Primary intraspinal neoplasms in Rochester, Minnesota, 1935—1981. Neuroepidemiology 2:156–163

    Google Scholar 

  • Schaberg J, Gainor BJ (1985) A profile of metastatic carcinoma of the spine. Spine 10:19–20

    PubMed  CAS  Google Scholar 

  • Schiff D, Shaw EG, Cascino TL (1995) Outcome after spinal reirradiation for malignant epidural spinal cord compression. Ann Neurol 37:583–589

    PubMed  CAS  Google Scholar 

  • Schiff D, Batchelor T, Wen PY (1998) Neurologic emergencies in cancer patients. Neurol Clin 16:449–483

    PubMed  CAS  Google Scholar 

  • Schoenthaler R, Castro JR, Petti PL et al (1993) Charged particle irradiation of sacral chordomas. Int J Radiat Oncol Biol Phys 26:291–298

    PubMed  CAS  Google Scholar 

  • Schouten LJ, Rutten J, Huveneers HA et al (2002) Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma. Cancer 94:2698–2705

    PubMed  Google Scholar 

  • Schultheiss TE (1999) The radiation dose response of the human cervical spinal cord [abstract]. Int J Radiat Oncol Biol Phys 45:174

    Google Scholar 

  • Schultheiss TE, Kun LE, Ang KK et al (1995) Radiation response of the central nervous system. Int J Radiat Oncol Biol Phys 31:1093–1112

    PubMed  CAS  Google Scholar 

  • Scott CB, Scarantino C, Urtasun R et al (1998) Validation and predictive power of Radiation Therapy Oncology Group (RTOG) recursive partitioning analysis classes for malignant glioma patients: a report using RTOG 90–06. Int J Radiat Oncol Biol Phys 40:51–55

    PubMed  CAS  Google Scholar 

  • Shaw E, Arusell R, Scheithauer B et al (2002) Prospective randomized trial of low-versus high-dose radiation therapy in adults with supratentorial low-grade glioma: initial report of a North Central Cancer Treatment Group/Radiation Therapy Oncology Group/Eastern Cooperative Oncology Group Study. J Clin Oncol 20:2267–2276

    PubMed  CAS  Google Scholar 

  • Shaw EG, Seiferheld W, Scott C et al (2003) Reexamining the radiation therapy oncology group (RTOG) recursive partitioning analysis (RPA) for glioblastoma multiforme (GBM) patients. Int J Radiat Oncol Biol Phys 57:S135–S136

    Google Scholar 

  • Shiu AS, Chang EL, Ye JS et al (2003) Near simultaneous computed tomography image-guided stereotactic spinal radiotherapy: an emerging paradigm for achieving true stereotaxy. Int J Radiat Oncol Biol Phys 57:605–613

    PubMed  Google Scholar 

  • Silber JH, Radcliffe J, Peckham V, Perilongo G, Kishnani P, Fridman M et al. (1992) Whole-brain irradiation and decline in intelligence: the influence of dose and age on IQ score. J Clin Oncol 10:1390–1396

    PubMed  CAS  Google Scholar 

  • Solit DB, Goldwein JW (1995) Posterior fossa: analysis of a popular technique for estimating the location in children with medulloblastoma. Radiology 195:697–698

    PubMed  CAS  Google Scholar 

  • Sorensen S, Helweg-Larsen S, Mouridsen H et al (1994) Effect of high-dose dexamethasone in carcinomatous metastatic spinal cord compression treated with radiotherapy: a randomized trial. Eur J Cancer 30A:22–27

    PubMed  CAS  Google Scholar 

  • Stafford SL, Perry A, Suman VJ et al (1998) Primarily resected meningiomas: outcome and prognostic factors in 581 Mayo Clinic patients, 1978 through 1988. Mayo Clin Proc 73:936–942

    PubMed  CAS  Google Scholar 

  • Stieber VW, deGuzman AF (2003) Pituitary. In: Perez C, Brady L, Schmidt-Ullrich R, Halperin E (eds) Principles and practice of radiation oncology. Lippincott Williams and Wilkins, New York

    Google Scholar 

  • Stieber VW, Munley M (2004) Central nervous system tumors. In: Mundt AJ, Roeske JC (eds) Intensity-modulated radiation therapy: a clinical perspective. Decker, Ontario

    Google Scholar 

  • Stieber V, Tatter S, Shaw EG (2005) Primary spinal tumors. In: Schiff D (ed) Cancer of the nervous system: principles and practice of neuro-oncology. McGraw-Hill, Columbus

    Google Scholar 

  • Tortosa A, Vinolas N, Villa S et al (2003) Prognostic implication of clinical, radiologic, and pathologic features in patients with anaplastic gliomas. Cancer 97:1063–1071

    PubMed  Google Scholar 

  • Vecht CJ, Haaxma-Reiche H, Noordijk EM et al (1993) Treatment of single brain metastasis: radiotherapy alone or combined with neurosurgery? Ann Neurol 33:583–590

    PubMed  CAS  Google Scholar 

  • Vecht CJ, Hovestadt A, Verbiest HB et al (1994) Dose-effect relationship of dexamethasone on Karnofsky performance in metastatic brain tumors: a randomized study of doses of 4, 8, and 16 mg per day. Neurology 44:675–680

    PubMed  CAS  Google Scholar 

  • Walker AE, Robins M, Weinfeld FD (1985) Epidemiology of brain tumors: the national survey of intracranial neoplasms. Neurology 35:219–226

    PubMed  CAS  Google Scholar 

  • Wara WM, Phillips TL, Sheline GE et al (1975) Radiation tolerance of the spinal cord. Cancer 35:1558–1562

    PubMed  CAS  Google Scholar 

  • Weiss E, Krebeck M, Kohler B et al (2001) Does the standardized helmet technique lead to adequate coverage of the cribriform plate? An analysis of current practice with respect to the ICRU 50 report. Int J Radiat Oncol Biol Phys 49:1475–1480

    PubMed  CAS  Google Scholar 

  • Weissman DE, Janjan NA, Erickson B et al (1991) Twice-daily tapering dexamethasone treatment during cranial radiation for newly diagnosed brain metastases. J Neurooncol 11:235–239

    PubMed  CAS  Google Scholar 

  • Wolfson AH, Snodgrass SM, Schwade JG et al (1994) The role of steroids in the management of metastatic carcinoma to the brain. A pilot prospective trial. Am J Clin Oncol 17:234–238

    PubMed  CAS  Google Scholar 

  • Wong DA, Fornasier VL, MacNab I (1990) Spinal metastases: the obvious, the occult, and the impostors. Spine 15:1–4

    PubMed  CAS  Google Scholar 

  • Working Group on Status Epilepticus and Epilepsy Foundation of America (1993) Treatment of convulsive status epilepticus. Recommendations of the Epilepsy Foundation of America’s Working Group on Status Epilepticus. JAMA 270:854–859

    Google Scholar 

  • Young RF, Post EM, King GA (1980) Treatment of spinal epidural metastases. Randomized prospective comparison of laminectomy and radiotherapy. J Neurosurg 53:741–748

    PubMed  CAS  Google Scholar 

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Stieber, V.W., McMullen, K.P., Munley, M.T., Shaw, E.G. (2006). Central Nervous System Tumors. In: Levitt, S.H., Purdy, J.A. (eds) Technical Basis of Radiation Therapy. Medical Radiology. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-35665-7_17

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