Skip to main content
SpringerLink
Log in
Book cover

Technical Basis of Radiation Therapy pp 379–394Cite as

Clinical Applications of High-Dose-Rate Brachytherapy

  • Chapter

  • 2836 Accesses

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   109.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Alekhteyar KM, Porter AT, Herskovic AM (1994) Preliminary results of hyperfractionated high dose rate brachytherapy in soft tissue sarcoma. Endocuriether Hypertherm Oncol 10:179–184

    Google Scholar 

  • Alektiar KM, Hu K, Anderson L et al (2000) High dose rate intraoperative radiation therapy (HDR-IORT) for retroperitoneal sarcomas. Int J Radiat Oncol Biol Phys 47:157–163

    Article  PubMed  CAS  Google Scholar 

  • Alektiar KM, Leung D, Zelefsky MJ et al (2002) Adjuvant brachytherapy for primary high-grade soft tissue sarcoma of the extremity. Ann Surg Oncol 9:48–56

    Article  PubMed  Google Scholar 

  • Alektiar KM, Ventakatraman E, Chi DS, Barakat RR (2005) Intravaginal brachytherapy alone for intermediate-risk endometrial cancer. Int J Radiat Oncol Biol Phys 62:111–117

    Article  PubMed  Google Scholar 

  • Arai T, Nakano T, Morita S, Sakashita K, Nakamura YK, Fukuhisa K (1992) High-dose-rate remote afterloading intracavitary radiation therapy for cancer of the uterine cervix: a 20-year experience. Cancer 69:175–180

    Article  PubMed  CAS  Google Scholar 

  • Arthur DW, Vicini F, Kuske RR, Wazer DE, Nag S (2002) Accelerated partial breast irradiation: an updated report from the American Brachytherapy Society. Brachytherapy 1:184–190

    Article  PubMed  Google Scholar 

  • Astrom L, Pederson D, Mercke C et al (2005) Long-term outcome of high dose rate brachytherapy in radiotherapy of localised prostate cancer. Radiother Oncol 74:157–161

    Article  PubMed  Google Scholar 

  • Aygun C, Weiner S, Scariato A et al (1992) Treatment of non-small cell lung cancer with external beam radiotherapy and high dose rate brachytherapy. Int J Radiat Oncol Biol Phys 23:127–132

    PubMed  CAS  Google Scholar 

  • Barendsen GW (1982) Dose fractionation, dose rate, and isoeffect relationships for normal tissue responses. Int J Radiat Oncol Biol Phys 8:1981–1997

    PubMed  CAS  Google Scholar 

  • Bedwinek J, Petty A, Bruton C et al (1992) The use of high dose rate endobronchial brachytherapy to palliate symptomatic endobronchial recurrence of previously irradiated bronchogenic carcinoma. Int J Radiat Oncol Biol Phys 22:23–30

    PubMed  CAS  Google Scholar 

  • Borghede G, Hedelin H, Holmang S, Johansson KA (1997) Combined treatment with temporary short-term high dose rate iridium-192 brachytherapy and external beam radiotherapy for irradiation of localized prostatic carcinoma. Radiother Oncol 44:237–244

    Article  PubMed  CAS  Google Scholar 

  • Chang LFL, Horvath J, Peyton W (1994) High dose rate after-loading intraluminal brachytherapy in malignant airway obstruction of lung cancer. Int J Radiat Oncol Biol Phys 28:589–596

    PubMed  CAS  Google Scholar 

  • Crownover RL, Marks KE, Zehr RJ (1997) Initial results with high dose rate brachytherapy for soft-tissue sarcomas. Sarcoma 1:196–205

    Google Scholar 

  • Demanes JD, Rodriguez RR, Schour L et al (2005) High dose rate intensity-modulated brachytherapy with external beam radiotherapy for prostate cancer: California Endocurietherapy’s 10 year results. Int J Radiat Oncol Biol Phys 61:1306–1316

    Article  PubMed  Google Scholar 

  • Dinges S, Deger S, Koswig S, Boehmer D (1998) High-dose rate interstitial with external beam irradiation for localized prostate cancer-results of a prospective trial. Radiother Oncol 48:197–202

    Article  PubMed  CAS  Google Scholar 

  • Dixit S, Baboo HA, Rakesh V (1997) Interstitial high dose rate brachytherapy in head and neck cancers: preliminary results. J Brachyther Int 13:363–370

    Google Scholar 

  • Donath D, Vuong T, Shnouda G et al (1995) The potential uses of high-dose-rate brachytherapy in patients with head and neck cancer. Eur Arch Otorhinolaryngol 252:321–354

    Article  PubMed  CAS  Google Scholar 

  • Duchesne GM, Peters LJ (1999) What is the α/β ratio for prostate cancer? Rationale for hypofractionated high-dose-rate brachytherapy. Int J Radiat Oncol Biol Phys 44:747–748

    Article  PubMed  CAS  Google Scholar 

  • Edmundson GK, Yan D, Martinez A (1995) Intraoperative optimization of needle placement and dwell times for conformal prostate brachytherapy. Int J Radiat Oncol Biol Phys 33:1257–1264

    Article  PubMed  CAS  Google Scholar 

  • Flamant F, Gerbaulet A, Nihoul-Fekete C et al (1990) Long-term sequelae of conservative treatment by surgery brachytherapy and chemotherapy for vulval and vaginal rhabdomyosarcoma in children. J Clin Oncol 8:1847–1853

    PubMed  CAS  Google Scholar 

  • Fowler J, Chappell R, Ritter M (2001) Is α/β for prostate tumors really low? Int J Radiat Oncol Biol Phys 50:1021–1031

    Article  PubMed  CAS  Google Scholar 

  • Fu K, Phillips T (1990) High-dose-rate versus low-dose-rate intracavitary brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys 19:791–796

    PubMed  CAS  Google Scholar 

  • Furuta M, Tsukiyama I, Ohno T et al (1999) Radiation therapy for roentogenographically occult lung cancer by external beam irradiation and endobronchial high dose rate brachytherapy. Lung Cancer 25:183–189

    Article  PubMed  CAS  Google Scholar 

  • Galalae RM, Martinez A, Mate T et al (2004) Long-term outcome by risk factors using conformal high dose rate brachytherapy (HDR-BT) boost with or without neoadjuvant androgen suppression for localized prostate cancer. Int J Radiat Oncol Biol Phys 58:1048–1055

    Article  PubMed  Google Scholar 

  • Gao Li, Xu Guo-zhen, Yin Wei-bo et al (1992) Preliminary experience in HDR brachytherapy for 72 nasopharyngeal carcinoma patients. In: Mould RF (ed) Brachytherapy in the Peoples Republic of China. Kowloon, Nucletron Far East, pp E76–E81

    Google Scholar 

  • Gaspar LE (1998) Brachytherapy in lung cancer. J Surg Oncol 67:60–70

    Article  PubMed  CAS  Google Scholar 

  • Gaspar LE, Nag S, Herskovic A, Mantravadi P, Speiser B (1997) American Brachytherapy Society (ABS) consensus guidelines for brachytherapy of esophageal cancer. Int J Radiat Oncol Biol Phys 38:127–132

    Article  PubMed  CAS  Google Scholar 

  • Grills IS, Martinez AA, Hollander M et al (2004) High-dose rate brachytherapy as prostate cancer monotherapy reduces toxicity compared to low dose rate palladium seeds. J Urology 171:1098–1104

    Article  Google Scholar 

  • Guix B, Finestres F, Tello J, Palma C (2000) Treatment of skin carcinomas of the face by high-dose-rate brachytherapy and custom-made surface molds. Int J Radiat Oncol Biol Phys 47:95–102

    Article  PubMed  CAS  Google Scholar 

  • Hareyama M, Sakata K, Oouchi A et al (2002) High-dose-rate versus low-dose-rate intracavitary therapy for carcinoma of the uterine cervix. A randomized trial. Cancer 94:117–124

    Article  PubMed  Google Scholar 

  • Harrison LB, Franzese F, Gaynor JJ, Brennan MF (1992) Long-term results of a prospective randomized trial of adjuvant brachytherapy in the management of completely resected soft tissue sarcomas of the extremity and superficial trunk. Int J Radiat Oncol Biol Phys 27:259–265

    Google Scholar 

  • Hishikawa Y, Kamikonya N, Tanaka S, Miura T (1987) Radiotherapy of esophageal carcinoma: role of high dose rate intracavitary irradiation. Radiother Oncol 9:13–20

    PubMed  CAS  Google Scholar 

  • Huber RM, Fischer R, Haútmann H et al (1997) Does additional brachytherapy improve the effect of external irradiation? A prospective, randomized study in central lung tumors. Int J Radiat Oncol Biol Phys 38:533–540

    Article  PubMed  CAS  Google Scholar 

  • Inoue T, Inoue T, Teshima T, Murayama S (1996) Phase III trial of high and low dose rate interstitial radiotherapy for early oral tongue cancer. Int J Radiat Oncol Biol Phys 36:1201–1204

    Article  PubMed  CAS  Google Scholar 

  • Jolly DE, Nag S (1992) Technique for construction of dental molds for high-dose-rate remote brachytherapy. Spec Care Dentist 12:219–224

    Article  PubMed  CAS  Google Scholar 

  • Khanavkar B, Stern P, Alberti W, Nakhosteen JA (1991) Complications associated with brachytherapy alone or with laser in lung cancer. Chest 99:1062–1065

    PubMed  CAS  Google Scholar 

  • Koizumi M, Inoue T, Yamazaki H et al (1999) Perioperative fractionated high-dose rate brachytherapy for malignant bone and soft tissue tumors. Int J Radiat Oncol Biol Phys 43:989–993

    Article  PubMed  CAS  Google Scholar 

  • Kuske RR, Bolton JS, Harrison W (1998) RTOG 95-17. A phase I/II trial to evaluate brachytherapy as the sole method of radiation therapy for stage I and II breast carcinoma. Radiation Therapy Oncology Group. Philadelphia, PA

    Google Scholar 

  • Lau HY, Hay JH, Flores AD et al (1996) Seven fractions of twice daily high dose-rate brachytherapy for node-negative carcinoma of the mobile tongue results in loss of therapeutic ratio. Radiother Oncol 39:15–18

    Article  PubMed  CAS  Google Scholar 

  • Leung TW, Wong VYW, Wong CM et al (1998) Technical hints for high dose rate interstitial tongue brachytherapy. Clin Oncol 10:231–236

    Article  CAS  Google Scholar 

  • Levendag PC, Vikram B, Flores AD et al (1994) High dose rate brachytherapy for cancer of the head and neck. In: Nag S (ed). High dose rate brachytherapy: a textbook. Futura Publishing Co., Armonk, NY, pp 237–273

    Google Scholar 

  • Li S, Frassica D, DeWeese T (2003) A real-time image-guided intraoperative high-dose-rate brachytherapy system. Brachytherapy 2:5–16

    Article  PubMed  Google Scholar 

  • Lorvidhaya V, Tonusin A, Changwiwit W, Chitapanarux I (2000) High-dose-rate afterloading brachytherapy in carcinoma of the cervix: and experience of 1992 patients. Int J Radiat Oncol Biol Phys 46:1185–1191

    Article  PubMed  CAS  Google Scholar 

  • Lybeert MLM, van Putten WLJ, Ribot JG, Crommelin MA (1989) Endometrial carcinoma: high dose rate brachytherapy in combination with external irradiation — a multivariate analysis of relapses. Radiother Oncol 16:245–252

    Article  PubMed  CAS  Google Scholar 

  • Macha HN, Wahlers B, Reichle C, von Zwehl (1995) Endobronchial radiation therapy for obstructing malignancies: ten years’ experience with iridium-192 high-dose radiation brachytherapy afterloading technique in 365 patients. Lung 173:271–280

    Article  PubMed  CAS  Google Scholar 

  • Mandell LM, Nori D, Anderson LL, Hilaris BS (1985) Postoperative vaginal radiation in endometrial cancer using a remote afterloading technique. Int J Radiat Oncol Biol Phys 11:473–478

    PubMed  CAS  Google Scholar 

  • Manning MA, Arthur DW, Schmidt-Ullrich RK et al (2000) Interstitial high dose rate brachytherapy boost: The feasibility and cosmetic outcome of a fractionated outpatient delivery scheme. Int J Radiat Oncol Biol Phys 48:1301–1306

    Article  PubMed  CAS  Google Scholar 

  • Marsiglia H, Baldeyrou P, Lartigau E et al (2000) High-dose-rate brachytherapy as a sole modality for early-stage endobronchial carcinoma. Int J Radiat Oncol Biol Phys 47:665–672

    Article  PubMed  CAS  Google Scholar 

  • Martinez A, Kestin L, Stromberg J (2000) Interim report of image guided conformal high dose rate brachytherapy for patients with unfavorable prostate cancer: the William Beaumont phase II dose escalating trial. Int J Radiat Oncol Biol Phys 47:343–352

    Article  PubMed  CAS  Google Scholar 

  • Martinez A, Pataki I, Edmundson G et al (2001) Phase II prospective study of the use of conformal high-dose rate brachytherapy as monotherapy for the treatment of favorable stage prostate cancer: a feasibility report. Int J Radiat Oncol Biol Phys 49:61–69

    Article  PubMed  CAS  Google Scholar 

  • Mehta MP, Petereit DG, Chosy L et al (1992) Sequential comparison of low dose rate and hyperfractionated high dose rate endobronchial radiation for malignant airway occlusion. Int J Radiat Oncol Biol Phys 23:133–139

    PubMed  CAS  Google Scholar 

  • Mehta MP, Lamond JP, Nori D, Speiser BL (1997) Brachytherapy of lung cancer. In: Nag S (ed). Principles and practice of brachytherapy. Futura Publishing Co., Armonk, NY, pp 323–349

    Google Scholar 

  • Merchant TE, Zelefsky MJ, Sheldon JM et al (1998) High-dose rate intraoperative radiation therapy for pediatric solid tumors. Med Ped Oncol 30:34–39

    Article  CAS  Google Scholar 

  • Nag S (1996) Modern techniques of radiation therapy for endometrial cancer. Clin Obstet Gynecol 39:728–744

    Article  PubMed  CAS  Google Scholar 

  • Nag S, Samsami N (2000) Pitfalls of inappropriate optimization. J Brachyther Int 16:187–198

    Google Scholar 

  • Nag S, Gupta N (2000) A simple method of obtaining equivalent doses for use in HDR brachytherapy. Int J Radiat Oncol Biol Phys 46:507–513

    Article  PubMed  CAS  Google Scholar 

  • Nag S, Hu KS (2003) Intraoperative high-dose-rate brachytherapy. Surg Oncol Clin N Am 12:1079–1097

    Article  PubMed  Google Scholar 

  • Nag S, Tippin D (2003) Brachytherapy for pediatric tumors. Brachytherapy 2:131–138

    Article  PubMed  Google Scholar 

  • Nag S, Olson T, Ruymann F et al (1995) High dose rate brachytherapy in childhood sarcomas: a local control strategy preserving bone growth and function. Med Ped Oncol 25:463–469

    CAS  Google Scholar 

  • Nag S, MartÍnez-Monge R, Ruymann FB, Bauer C (1998) Feasibility of intraoperative high-dose rate brachytherapy to boost low dose external beam radiation therapy to treat pediatric soft tissue sarcomas. Med Ped Oncol 31:79–85

    Article  CAS  Google Scholar 

  • Nag S, Gunderson L, Harrison L (1999) Techniques of intraoperative radiation therapy vs. intraoperative high dose rate brachytherapy. In: Intraoperative irradiation: techniques and results. Gunderson LL, Willet CG, Harrison LV, Calvo FA (eds) Humana Press, Totowa, NJ, pp 111–130

    Google Scholar 

  • Nag S, Erickson B, Parikh S, Gupta N, Varia M, Glasgow G (2000a) The American Brachytherapy Society recommendations for HDR brachytherapy for carcinoma of the endometrium. Int J Radiat Oncol Biol Phys 48:779–790

    Article  PubMed  CAS  Google Scholar 

  • Nag S, Erickson B, Thomadsen B, Orton C, Demanes JD, Petereit D (2000b) The American Brachytherapy Society recommendations for HDR brachytherapy of the cervix. Int J Radiat Oncol Biol Phys 48:201–211

    Article  PubMed  CAS  Google Scholar 

  • Nag S, Kelly JF, Horton JL, Komaki R, Nori D (2001a) The American Brachytherapy Society recommendations for HDR brachytherapy for carcinoma of the lung. Oncology 15:371–381

    PubMed  CAS  Google Scholar 

  • Nag S, Kuske RR, Vicini F, Arthur DW, Zwicker RD (2001b) The American Brachytherapy Society recommendations for brachytherapy for carcinoma of the breast. Oncology 15:195–207

    PubMed  CAS  Google Scholar 

  • Nag S, Shasha D, Janjan N, Petersen I, Zaider M (2001c) The American Brachytherapy Society recommendations for brachytherapy of soft tissue sarcomas. Int J Radiat Oncol Biol Phys 49:1033–1043

    Article  PubMed  CAS  Google Scholar 

  • Nag S, Tippin D, Ruymann FB (2001d) Intraoperative high-dose-rate brachytherapy for the treatment of pediatric soft tissue sarcomas. Int J Radiat Oncol Biol Phys 51:729–735

    Article  PubMed  CAS  Google Scholar 

  • Nag S, Vikram B, Demanes JD, Cano E, Puthawala AA (2001e) The American Brachytherapy Society recommendations for HDR brachytherapy for head and neck carcinoma. Int J Radiat Oncol Biol Phys 50:1190–1198

    Article  PubMed  CAS  Google Scholar 

  • Nag S, Dally M, De la Torre M et al (2002) Recommendations for implementation of high dose rate 192Ir brachytherapy in developing countries by the advisory group of international atomic energy agency. Radiother Oncol 64:297–308

    Article  PubMed  Google Scholar 

  • Nag S, Tippin D, Ruymann FB (2003) Long term morbidity in children treated with fractionated high dose rate brachytherapy for soft tissue sarcomas. J Pediatr Hematol Oncol 25:448–452

    Article  PubMed  Google Scholar 

  • Nag S, Cardenes H, Chang S et al (2004a) Proposed guidelines for image-based intracavitary brachytherapy for cervical carcinoma: a report from the image-guided brachytherapy working group. Int J Radiat Oncol Biol Phys 60:1160–1172

    Article  PubMed  Google Scholar 

  • Nag S, Tippin D, Grecula J, Schuller D (2004b) Intraoperative high dose rate brachytherapy for paranasal sinus tumors. Int J Radiat Oncol Biol Phys 58:155–160

    Article  PubMed  Google Scholar 

  • Nag S, Koc M, Schuller D, Tippin D, Grecula JC (2005) Intraoperative single fraction high dose rate brachytherapy for head and neck cancers. Brachytherapy 4:217–223

    Article  PubMed  Google Scholar 

  • Nakano T, Kato S, Ohno T et al (2005) Long-term results of high-dose-rate intracavitary brachytherapy for squamous cell carcinoma of the uterine cervix. Cancer 103:92–101

    Article  PubMed  Google Scholar 

  • Nori D, Merimsky O, Batata M et al (1994) Postoperative high-dose-rate intravaginal brachytherapy combined with external irradiation for early stage endometrial cancer: A long term follow-up. Int J Radiat Oncol Biol Phys 30:831–837

    PubMed  CAS  Google Scholar 

  • Orton CG, Seyedsadr M, Somnay A (1991) Comparison of high and low dose rate remote afterloading for cervix cancer and the importance of fractionation. Int J Radiat Oncol Biol Phys 21:1425–1434

    PubMed  CAS  Google Scholar 

  • Patel FD, Sharma SC, Negi PS et al (1993) Low dose rate versus high dose rate brachytherapy in the treatment of carcinoma of the uterine cervix: A clinical trial. Int J Radiat Oncol Biol Phys 28:335–341

    Google Scholar 

  • Patel FD, Rai B, Mallick I, Sharma SC (2005) High dose rate brachytherapy in uterine cervical carcinoma. Int J Radiat Oncol Biol Phys 62:125–130

    Article  PubMed  Google Scholar 

  • Perol M, Caliandro R, Pommier P, Malet C (1997) Curative irradiation of limited endobronchial carcinomas with high-dose-rate brachytherapy. Results of a pilot study. Chest 111:1417–1423

    PubMed  CAS  Google Scholar 

  • Petereit DG, Sarkaria JN, Potter DM, Schink JC (1999) High dose-rate versus low-dose-rate brachytherapy in the treatment of cervical cancer: analysis of tumor recurrence — the University of Wisconsin experience. Int J Radiat Oncol Biol Phys 45:1267–1274

    Article  PubMed  CAS  Google Scholar 

  • Polgar C, Major T, Somogyi A, Fodor J et al (2004) High-dose-rate brachytherapy alone versus whole breast radiotherapy with or without tumor bed boost after breast-conserving surgery: seven-year results of a comparative study. Int J Radiat Oncol Biol Phys 60:1173–1181

    Article  PubMed  Google Scholar 

  • Poortmans P, Bartelink H, Horiot JC et al (2004) The influence of the boost technique on local control in breast conserving treatment in the EORTC ‘boost versus no boost’ randomized trial. Radiother Oncol 72:25–33

    Article  PubMed  Google Scholar 

  • Rodriguez R, Nag S, Mate T, Martinez, A, Shasha D, Orton C, Tripuraneni P, Linares L, Kelly D, Gustafson G, Devlin P, Alteiri G, Gribble M, Rao J, Perez C, Syed N (2001) High Dose rate brachytherapy for prostate cancer: assessment of current clinical practice and recommendations of the American Brachytherapy Society. J Brachyther Int 17:265–282

    Google Scholar 

  • Romestaing P, Lehingue Y, Carrie C, Coquard R, Montbarbon X, Ardiet JM, Mamelle N, Gerard JP (1997) Role of a 10 Gy boost in the conservative treatment of early breast cancer: results of a randomized clinical trial in Lyon, France. J Clin Oncol 15:963–968

    PubMed  CAS  Google Scholar 

  • Rouanet P, Dubois JB, Gely S et al (1993) Exclusive radiation therapy in endometrial carcinoma. Int J Radiat Oncol Biol Phys 26:223–228

    PubMed  CAS  Google Scholar 

  • Saito M, Yokoyama A, Kurita Y, Uematsu T, Tsukada H, Yamanoi T (2000) Treatment of roentgenographically occult endobronchial with external beam radiotherapy and intraluminal low dose rate brachytherapy: second report. Int J Radiat Oncol Biol Phys 47:673–680

    Article  PubMed  CAS  Google Scholar 

  • Shah NM, Tenenholz T, Arthur D et al (2004) MammoSite and interstitial brachytherapy for accelerated partial breast irradiation: factors that affect toxicity and cosmesis. Cancer 101:727–734

    Article  PubMed  Google Scholar 

  • Shigematsu Y, Nishiyama K, Masaki N, Inoue T (1983) Treatment of carcinoma of the uterine cervix by remotely controlled afterloading intracavitary radiotherapy with high-does rate: a comparative study with a low-dose rate system. Int J Radiat Oncol Biol Phys 9:351–356

    PubMed  CAS  Google Scholar 

  • Sood BM, Gorla G, Gupta S et al (2002) Two fractions of high dose rate brachytherapy in the management of cervix cancer: clinical experience with and without chemotherapy. Int J Radiat Oncol Biol Phys 53:702–706

    Article  PubMed  Google Scholar 

  • Sorbe B, Frankendal B (1989) Intracavitary irradiation of endometrial carcinoma stage I by a high dose rate afterloading technique. Gynecol Oncol 33:135–145

    Article  PubMed  CAS  Google Scholar 

  • Sorbe BG, Smeds AC (1990) Postoperative vaginal irradiation with high dose rate afterloading technique in endometrial carcinoma stage I. Int J Radiat Oncol Biol Phys 18:305–314

    PubMed  CAS  Google Scholar 

  • Sorbe B, Kjelligren O, Stenson S (1990) Prognosis of endometrial carcinoma stage I in two Swedish regions. A study with special regard to the effects of intracavitary irradiation with high dose rate afterloading technique. Acta Oncol 29:29–37

    PubMed  CAS  Google Scholar 

  • Speiser BL (1999) Brachytherapy in the treatment of thoracic tumors. Lung and esophageal. Hematol Oncol Clin North Am 13:609–634

    Article  PubMed  CAS  Google Scholar 

  • Speiser B, Spratling L (1993a) Fatal hemoptysis: complication or failure of treatment. Int J Radiat Oncol Biol Phys 25:925

    PubMed  CAS  Google Scholar 

  • Speiser BL, Spartling L (1993b) Radiation bronchitis and stenosis secondary to high dose rate endobronchial irradiation. Int J Radiat Oncol Biol Phys 25:589–597

    PubMed  CAS  Google Scholar 

  • Strnad V, Ott O, Potter R et al (2004) Interstitial brachytherapy alone after breast conserving surgery: interim results of a German-Austrian multicenter phase II trial. Brachytherapy 3:115–119

    Article  PubMed  Google Scholar 

  • Sur R, Donde B, Falkson C et al (2004) Randomized prospective study comparing high dose rate intraluminal brachytherapy (HDRILBT) alone to HDRILBT and external beam radiotherapy in the palliation of advanced esophageal cancer. Brachytherapy 3:191–195

    Article  PubMed  Google Scholar 

  • Sur RK, Levin CV, Donde B et al (2002) Prospective randomized trial of HDR brachytherapy as a sole modality in palliation of advanced esophageal carcinoma — an international atomic energy agency study. Int J Radiat Oncol Biol Phys 53:127–133

    Article  PubMed  Google Scholar 

  • Svoboda VH, Kovarik J, Morris F (1995) High dose-rate microselectron molds in the treatment of skin tumors. Int J Radiat Oncol Biol Phys 31:967–972

    Article  PubMed  CAS  Google Scholar 

  • Yoshioka Y, Nose T, Yoshida K et al (2003) High-dose rate brachytherapy as monotherapy for localized prostate cancer: a retrospective analysis with special focus on tolerance and chronic toxicity. Int J Radiat Oncol Biol Phys 56:213–220

    Article  PubMed  Google Scholar 

  • Yu L, Vikram B, Chadha M (1996) High dose rate interstitial brachytherapy in patients with cancers of the head and neck. Endocuriether Hyperther Oncol 12:1–6

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiation Medicine, Arthur G. James Cancer Hospital and Solove Research Institute, The Ohio State University, 300 West Tenth Avenue, Columbus, OH, 43210, USA

    Subir Nag MD, FACR, FACRO (Chief of Brachytherapy)

Authors
  1. Subir Nag MD, FACR, FACRO
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Therapeutic Radiation, Oncology MMC 436, University of Minnesota Hospital, 420 Delaware St SE, Minneapolis, MN, 55455, USA

    Seymour H. Levitt MD (Professor and Foreign Adjunct Professor) (Professor and Foreign Adjunct Professor)

  2. Karolinska Institute Stockholm, Sweden

    Seymour H. Levitt MD (Professor and Foreign Adjunct Professor) (Professor and Foreign Adjunct Professor)

  3. Department of Radiation Oncology, UC Davis Medical Center, 4501 X Street, Suite G140, Sacramento, CA, 95817, USA

    James A. Purdy PhD (Professor, Vice Chairman and Chief) (Professor, Vice Chairman and Chief)

  4. Physics Section, UC Davis Medical Center, 4501 X Street, Suite G140, Sacramento, CA, 95817, USA

    James A. Purdy PhD (Professor, Vice Chairman and Chief) (Professor, Vice Chairman and Chief)

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Nag, S. (2006). Clinical Applications of High-Dose-Rate Brachytherapy. In: Levitt, S.H., Purdy, J.A. (eds) Technical Basis of Radiation Therapy. Medical Radiology. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-35665-7_15

Download citation

  • DOI: https://doi.org/10.1007/3-540-35665-7_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-21338-3

  • Online ISBN: 978-3-540-35665-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation