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Gynaecomastia and Benign Breast Hyperplasia Including Iatrogenic Causes

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Andrology for the Clinician

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References

  • Ambrogetti D, Ciatto S, Catarzi S, Muraca MG (1996) The combined diagnosis of male breast lesions: a review of a series of 748 consecutive cases. Radiol Med (Torino) 91:356–359

    CAS  PubMed  Google Scholar 

  • Amrikachi M, Green LK, Rone R, Ramzy I (2001) Gynecomastia: cytologic features and diagnostic pitfalls in fine needle aspirates. Acta Cytol 45:948–952

    PubMed  CAS  Google Scholar 

  • Appelbaum AH, Evans GF, Levy KR, Amirkhan RH, Schumpert TD (1999) Mammographic appearances of male breast disease. Radiographics 19:559–568

    PubMed  CAS  Google Scholar 

  • Bernard-Gallon DJ, Dechelotte PJ, Le Corre L, Vissac-Sabatier C, Favy DA, Cravello L, De Latour MP, Bignon YJ (2003) Expression of BRCA1 and BRCA2 in male breast cancers and gynecomastias. Anticancer Res 23:661–667

    PubMed  CAS  Google Scholar 

  • Calzada L, Torres-Calleja J, Martinez JM, Pedron N (2001) Measurement of androgen and estrogen receptors in breast tissue from subjects with anabolic steroid-dependent gynecomastia. Life Sci 69:1465–1469

    Article  PubMed  CAS  Google Scholar 

  • Coppola A, Cuomo MA (1998) Prolactinoma in themale. Physiopathological, clinical, and therapeutic features. Minerva Endocrinol 23:7–16

    PubMed  CAS  Google Scholar 

  • Damsa C, Bumb A, Bianchi-Demicheli F, Vidailhet P, Sterck R, Andreoli A, Beyenburg S (2004) “Dopamine-dependent” side effects of: a clinical review. J Clin Psychiatry 65:1064–1068

    Article  PubMed  CAS  Google Scholar 

  • Daniels IR, Layer GT (2003) Testicular tumours presenting as gynaecomastia. Eur J Surg Oncol 29:437–439

    Article  PubMed  CAS  Google Scholar 

  • Das DK, Junaid TA, Mathews SB et al (1995) Fine needle aspiration cytology diagnosis of male breast lesions. Acta Cytol 39:870–876

    PubMed  CAS  Google Scholar 

  • De Jong MM, Nolte IM, te Meerman GJ, van der Graaf WT, Oosterwijk JC, Kleibeuker JH, Schaapveld M, de Vries EG (2002) Genes other than BRCA1 and BRCA2 involved in breast cancer susceptibility. J Med Genet 39:225–242

    Article  PubMed  Google Scholar 

  • Doughty JC, Wilson CR (2003) Tamoxifen is unproved for gynaecomastia (letter). BMJ 327:1050

    Article  PubMed  Google Scholar 

  • Frank TS, Deffenbaugh AM, Reid JE, Hulick M, Ward BE, Lingenfelter B, Gumpper KL, Scholl T, Tavtigian SV, Pruss DR, Critchfield GC (2002) Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: analysis of 10,000 individuals. J Clin Oncol 20:1480–1490

    Article  PubMed  CAS  Google Scholar 

  • Gatalica Z, Norris BA, Kovatich AJ (2000) Immunohistochemical localization of prostate-specific antigen in ductal epithelium of male breast. Potential diagnostic pitfall in patients with gynecomastia. Appl Immunohistochem Mol Morphol 8:158–161

    Article  PubMed  CAS  Google Scholar 

  • Gill MS, Kayani N, Khan MN, Hasan SH (2000) Breast diseases in males-a morphological review of 150 cases. J Pak Med Assoc 50:177–179

    PubMed  CAS  Google Scholar 

  • Giordano SH, Buzdar AU, Hortobagyi GN (2002) Breast cancer in men. Ann Intern Med 137:678–687

    PubMed  Google Scholar 

  • Hunfeld KP, Bassler R, Kronsbein H (1997) “Diabetic mastopathy” in the male breast-a special type of gynecomastia. A comparative study of lymphocyticmastitis and gynecomastia. Pathol Res Pract 193:197–205

    PubMed  CAS  Google Scholar 

  • Ioulios P, Charalampos M, Efrossini T (2003) The spectrum of cutaneous reactions associated with calcium antagonists: a review of the literature and the possible etiopathogenic mechanisms. Dermatol Online J 9:6

    PubMed  Google Scholar 

  • Joshi A, Kapila K, Verma K (1999) Fine needle aspiration cytology in the management of male breast masses. Nineteen years of experience. Acta Cytol 43:334–338

    PubMed  CAS  Google Scholar 

  • Jover F, Cuadrado JM, Roig P, Rodriguez M, Andreu L, Merino J (2004) Efavirenz-associated gynecomastia: report of five cases and review of the literature. Breast J 10:244–246

    Article  PubMed  Google Scholar 

  • Jun Yang Y (2002) Gynecomastia with marked cellular atypia associated with chemotherapy. Arch Pathol Lab Med 126:613–614

    PubMed  Google Scholar 

  • Khan HN, Blamey KW (2003) Endocrine treatment of physiological gynaecomastia. Tamoxifen seems to be effective. BMJ 327:301–302

    Article  PubMed  Google Scholar 

  • Kidwai N, Gong Y, Sun X, Deshpande CG, Yeldandi AV, Rao MS, Badve S (2004) Expression of androgen receptor and prostate-specific antigen in male breast carcinoma. Breast Cancer Res 6:R18–R23

    Article  PubMed  CAS  Google Scholar 

  • Krause W, Splieth B (1996) Erkrankungen der männlichen Brustdrüse. Hautarzt 47:422–426

    Article  PubMed  CAS  Google Scholar 

  • Labhart A, Hedinger C, Kistler G, Müller J, et al (1978) Testis. In Labhart Klinik der inneren Sekretion, 3. Auflage, Springer, Berlin Heidelberg New York, pp 497–499

    Google Scholar 

  • Leiber B (1995) Aspekte eines polyätiologischen Symptoms: Gynäkomastie. Gyne 116: 237–241

    Google Scholar 

  • Llort G, Munoz CY, Tuser MP, Guillermo IB, Lluch JR, Bale AE, Franco MA (2002) Low frequency of recurrent BRCA1 and BRCA2 mutations in Spain. Hum Mutat 19:307

    Article  PubMed  Google Scholar 

  • Magro G, Gurrera A, Scavo N, Lanzafame S, Bisceglia M (2002) Fibromatosis of the breast: a clinical, radiological and pathological study of 6 cases. Pathologica 94:238–246

    Article  PubMed  CAS  Google Scholar 

  • Mcleod DG (2002) Emerging role of adjuvant hormonal therapy. Urology 60[3 Suppl 1]:13–20

    Article  PubMed  Google Scholar 

  • McLeod DG, Iversen P (2000) Gynecomastia in patients with prostate cancer: a review of treatment options. Urology 56:713–720

    Article  PubMed  CAS  Google Scholar 

  • Merkle E, Muller M, Vogel J, Klatt S, Gorich J, Beger HG, Brambs HJ (1996) Clinical relevance of mammography in men. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 164:7–12

    Article  PubMed  CAS  Google Scholar 

  • Milazzo G, Yip CC, Maddux BA, Vigneri R, Goldfine ID (1992) High-affinity insulin binding to an atypical insulin-like growth factor-I receptor in human breast cancer cells. J Clin Invest 89:899–908

    Article  PubMed  CAS  Google Scholar 

  • Niewöhner CB, Nuttall RQ (1984) Gynecomastia in a hospitalized male population. Am J Med 77:633–638

    Article  Google Scholar 

  • O’Hanlon DM, Kent P, Kerin MJ, Given HF (1995) Unilateral breast masses in men over 40: a diagnostic dilemma. Am J Surg 825:170:24–26

    Article  Google Scholar 

  • Olsson H, Bladstrom A, Alm P (2002) Male gynecomastia and risk for malignant tumors — a cohort study. BMC Cancer 2:26

    Article  PubMed  CAS  Google Scholar 

  • Rohrich RJ, Ha RY, Kenkel JM, Adams WP Jr (2003) Classification and management of gynecomastia: defining the role of ultrasound-assisted liposuction. Plast Reconstr Surg 111:909–923

    Article  PubMed  Google Scholar 

  • Satoh T, Munakata H, Fujita K, Itoh S, Itoh S, Kamataki T, Yoshizawa I (2003) Studies on the interactions between drug and estrogen. II. On the inhibitory effect of 29 drugs reported to induce gynecomastia on the oxidation of estradiol at C-2 or C-17. Biol Pharm Bull 26:695–700

    Article  PubMed  CAS  Google Scholar 

  • Scheike O, Visfeldt J, Petersen B (1973) Male breast cancer. 4. Gynecomastia in patients with breast cancer. Arch PathMicrobiol Scand A 81:359–365

    CAS  Google Scholar 

  • Schinina V, Busi Rizzi E, Zaccarelli M, Carvelli C, Bibbolino C (2002) Gynecomastia in male HIV patients MRI and US findings. Clin Imaging 26:309–313

    Article  PubMed  Google Scholar 

  • Seibel V, Müller HH, Krause W (1998) Die Inzidenz der Gynäkomastie bei dermatologischen Patienten. Hautarzt 49:382–387

    Article  PubMed  CAS  Google Scholar 

  • Shozu M, Sebastia S, Takayama K, Wei-Tong Hsu, Schultz RA, Neely K, Bryant M, Bulun SE (2003) Estrogen excess associated with novel gain-of functionmutation affecting the aromatase gene. New Engl J Med 348:1855–1865

    Article  PubMed  CAS  Google Scholar 

  • Siddiqui MT, Zakowski MF, Ashfaq R, Ali SZ (2002) Breast masses in males: multi-institutional experience on fine-needle aspiration. Diagn Cytopathol 26:87–91

    Article  PubMed  Google Scholar 

  • Tyrrell CJ, Payne H, Tammela TL, Bakke A, Lodding P, Goedhals L, Van Erps P, Boon T, Van De Beek C, Andersson SO, Morris T, Carroll K (2004) Prophylactic breast irradiation with a single dose of electron beam radiotherapy (10 Gy) significantly reduces the incidence of bicalutamide-induced gynecomastia. Int J Radiat Oncol Biol Phys 60:476–483

    Article  PubMed  Google Scholar 

  • Vesoulis Z, Kashkari S (1998) Fine needle aspiration of secretory breast carcinoma resembling lactational changes. A case report. Acta Cytol 42:1032–1036

    PubMed  CAS  Google Scholar 

  • Vetto J, Schmidt W, Pommier R, DiTomasso J, Eppich H, Wood W, Moseson D (1998) Accurate and cost-effective evaluation of breast masses in males. Am J Surg 175:383–387

    Article  PubMed  CAS  Google Scholar 

  • Volpe CM, Raffetto JD, Collure DW, Hoover EL, Doerr RJ (1999) Unilateral male breast masses: cancer risk and their evaluation and management. Am Surg 65:250–253

    PubMed  CAS  Google Scholar 

  • Westenend PJ, Jobse C (2002) Evaluation of fine-needle aspiration cytology of breast masses in males. Cancer 96:101–104

    Article  PubMed  Google Scholar 

  • Williams MJ (1963) Gynecomastia. Its incidence, recognition and host characterization in 447 autopsy cases. Am J Med 34:103–112

    Article  PubMed  CAS  Google Scholar 

  • Yang WT, Whitman GJ, Yuen EH, Tse GM, Stelling CB (2001) Sonographic features of primary breast cancer in men. AJR Am J Roentgenol 176:413–416

    PubMed  CAS  Google Scholar 

  • Zimmerman RL, Fogt F, Cronin D, Lynch R (2000) Cytologic atypia in a 53-year-old man with finasteride-induced gynecomastia. Arch Pathol Lab Med 124:625–627

    PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Andrology and Venerology, University Hospital, Philipp University, 35033, Marburg, Germany

    W. Krause

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  1. W. Krause
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Editor information

Editors and Affiliations

  1. Center of Dermatology and Andrology, Justus Liebig University Giessen, Gaffystraße 14, 35385, Giessen, Germany

    Wolf-Bernhard Schill

  2. Center for Medical and Urological Andrology and Reproductive Endocrinology, University Hospital Ghent 6K12IE, De Pintelaan 185, 9000, Ghent, Belgium

    Frank Comhaire

  3. Department of Oncology, University of Edinburgh, Western General Hospital, Human Genetics Building, Edinburgh, EH4 2XU, Scotland UK

    Timothy B. Hargreave

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© 2006 Springer-Verlag Berlin Heidelberg

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Krause, W. (2006). Gynaecomastia and Benign Breast Hyperplasia Including Iatrogenic Causes. In: Schill, WB., Comhaire, F., Hargreave, T.B. (eds) Andrology for the Clinician. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-33713-X_50

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  • DOI: https://doi.org/10.1007/3-540-33713-X_50

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-23171-4

  • Online ISBN: 978-3-540-33713-3

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