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Trauma: Bleeding, Coagulopathy, and Blood Component Transfusion

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Yearbook of Intensive Care and Emergency Medicine

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 2006))

Conclusion

The resuscitation of patients with trauma and hemorrhagic shock has improved over recent years but there is still a need to control bleeding that cannot be corrected surgically, particularly coagulopathic bleeding, in order to reduce the morbidity and mortality associated with major trauma.

Although blood component therapy remains the mainstay of management for coagulopathic bleeding, and RBC transfusion can be life-saving, many patients remain at risk of exsanguination, and there are well-documented post-injury problems associated with high rates of RBC transfusion in trauma. Hemostatic agents may offer effective adjunctive control in cases of coagulopathic bleeding, helping to reduce the reliance on transfusion and potentially decreasing the morbidity and mortality burden.

Blood transfusion therapy is unlikely to be replaced completely, but the role of new agents capable of improving bleeding control in emergency settings clearly warrants close consideration and further study.

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Author information

Authors and Affiliations

  1. Department of Anesthesiology, University Hospital, Pauwelsstraße 30, 52074, Aachen, Germany

    R. Rossaint

  2. Department of Anesthesiology, University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland

    D. R. Spahn

Authors
  1. R. Rossaint
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  2. D. R. Spahn
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Head) (Head)

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© 2006 Springer-Verlag Berlin Heidelberg

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Rossaint, R., Spahn, D.R. (2006). Trauma: Bleeding, Coagulopathy, and Blood Component Transfusion. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 2006. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-33396-7_24

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  • DOI: https://doi.org/10.1007/3-540-33396-7_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-30155-4

  • Online ISBN: 978-3-540-33396-8

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