Zusammenfassung
Muskelrelaxanzien sind Substanzen, die eine reversible Lähmung der Skelettmuskulatur bewirken. Ihre Anwendung erfolgt in der Anästhesie und Notfallmedizin vor allem, um die endotracheale Intubation zu ermöglichen und um bei bestimmten Operationen eine vollständige Erschlaffung der Muskulatur zur Verbesserung der Operationsbedingungen zu erzielen. In deutlich geringem Maße werden Muskelrelaxanzien in der Intensivmedizin eingesetzt, um die Beatmung zu erleichtern und bei Bedarf eine völlig Ruhigstellung des Patienten zu erzielen.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Berg H, Roed J, Viby-Mogensen J et al. (1997) Residual neuromuscular block is a risk factor or pulmonary complications. A prospective, randomized and double blind study of postoperative pulmonary complications after atracurium, vecuronium and pancuronium. Acta Anaesth Scand 41: 1095–1103
Debaene B, Plaud B, Dilly MP, Donati F (2003) Residual paralysis in the PACU after a single intubating dose of nondepolarizing muscle relaxant with an intermediate duration of action. Anesthesiology 98: 1042–1048
Erikkson LI (2003) Evidence-based practice and neuromuscular monitoring: it’s time for routine quantitative assessment. Anesthesiology 98: 1037–1039
Eriksson LI, Sundman E, Olsson R et al. (1997) Functional assessment of the pharynx at rest and during swallowing in partially pralyzed humans: simultaneous videomanometry and mechanomyography of awake volunteers. Anesthesiology 87: 1035–1043
Eyzaguirre C, Monti-Bloch L (1982) Nicotinergic and muscarinic reactive sites in mammalian glomus cells. Brain Res 252: 181–184
Fitzgerald RS, Shirahata M (1994) Acetylcholine and carotid body excitation during hypoxemia in the cat. J Appl Physiol: pharmakokinetische Daten 76: 1566–1574
Kopman AF, Zhaku B, Lai KS (2003) The intubating dose of succinylcholine: the effect of decreasing doses on recovery time. Anesthesiology 99: 1050–1054
Paton WDM, Waud DR (1967) The margin of savety of muscle relaxant drugs. J Physiol 191: 59–90
Silverman DG (1994) Neuromuscular block in perioerative and intensive care. Lippincrott-Raven, Philadelphia
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer Medizin Verlag Heidelberg
About this chapter
Cite this chapter
Pühringer, F.K. (2006). Pharmakologisches Wissen — Muskelrelaxanzien. In: Kretz, FJ., Teufel, F. (eds) Anästhesie und Intensivmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-32808-4_4
Download citation
DOI: https://doi.org/10.1007/3-540-32808-4_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-62739-5
Online ISBN: 978-3-540-32808-7
eBook Packages: Medicine (German Language)