Skip to main content
SpringerLink
Log in

Active Coating of Implants used in Orthopedic Surgery

  • Chapter
Practice of Intramedullary Locked Nails

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Beck A, Kinzl L, Bischoff M (1999) [Antibiotic prophylaxis and therapy in trauma surgery]. Unfallchirurg 102: 955–966.

    Article  CAS  PubMed  Google Scholar 

  2. Coventry M, Nolan D, Bukenbauch R (1973) “Delayed” prophylactic anticoagulation: a study of results and complications in 2,012 total hip arthroplasties. J Bone Joint Surg 55: 1487–1492.

    CAS  PubMed  Google Scholar 

  3. Einhorn TA (1995) Enhancement of fracture healing. J Bone Joint Surg Am 77: 940–956.

    CAS  PubMed  Google Scholar 

  4. Einhorn TA, Lane JM (1998) Significant advances have been made in the way surgeons treat fractures [editorial]. Clin Orthop S2–S3.

    Google Scholar 

  5. Fujimoto R, Tanizawa T, Nishida S, Yamamoto N, Soshi S, Endo N, Takahashi HE (1999) Local effects of transforming growth factor-betal on rat calvaria: changes depending on the dose and the injection site. J Bone Miner Metab 17: 11–17.

    CAS  PubMed  Google Scholar 

  6. Gristina AG, Costerton JW (1985) Bacterial adherence to biomaterials and tissue. The significance of its role in clinical sepsis. J Bone Joint Surg Am 67: 264–273.

    CAS  PubMed  Google Scholar 

  7. Kandziora F, Pflugmacher R, Scholz M, Schäfer J, Schollmeier G, Schmidmaier G, Duda G, Raschke M, Haas NP (2003) Dose-dependent effects of combined IGF-I and TGF-β1 application in a sheep cervical spine fusion model. Eur Spine J 12: 464–473.

    Article  CAS  PubMed  Google Scholar 

  8. Kandziora F, Bail H, Schmidmaier G, Schollmeier G, Scholz M, Knispel C, Hiller T, Pflugmacher R, Mittlmeier T, Raschke M, Haas NP (2002) Bone morphogenic protein-2 application by a poly(D,L-lactide)-coated interbodycage: in vivo results of a new carrier for growth factors. J Neurosurg (Spine 1) 97: 40–48.

    CAS  PubMed  Google Scholar 

  9. Kandziora F, Schmidmaier G, Schollmeier G, Bail H, Pflugmacher R, Gorke T, Wagner M, Raschke M, Mittlmeier T, Haas NP (2002) IGF-I and TGF-betal application by a poly-(D,L-lactide)-coated cage promotes intervertebral bone matrix formation in the sheep cervical spine. Spine 27: 1710–1723.

    PubMed  Google Scholar 

  10. Li RH, Wozney JM (2001) Delivering on the promise of bone morphogenetic proteins. Trends Biotechnol 19: 255–265.

    Article  CAS  PubMed  Google Scholar 

  11. Littlewood EA, Hattenberger M, Zak O, O’Reilly T (1997) Effect of combination therapy of rifampicin and azithromycin on TNF levels during a rat model of chronic osteomyelitis. J Antimicrob Chemother 39: 493–498.

    Google Scholar 

  12. Lucke M, Schmidmaier G, Sadoni S, Wildemann B, Schiller R, Haas N, Raschke M (2003) Gentamicin coating of metallic implants reduces implant related osteomyelitis in rats. Bone 32: 521–531.

    Article  CAS  PubMed  Google Scholar 

  13. Lucke M, Schmidmaier G, Sadoni S, Wildemann B, Schiller R, Stemberger A, Haas N, Raschke M (2003) A new model of implant related osteomyelitis in rats. J Biomed Mater Res 67B: 593–602.

    Article  CAS  Google Scholar 

  14. Raschke M, Wildemann B, Inden P, Bail H, Flyvbjerg A, Hoffmann J, Haas NP, Schmidmaier G (2002) Insulin-like growth factor-1 and transforming growth factor-betal accelerates osteotomy healing using polylactide-coated implants as a delivery system: a biomechanical and histological study in minipigs. Bone 30(1): 144–151.

    Article  CAS  PubMed  Google Scholar 

  15. Raschke M, Kolbeck S, Bail H, Schmidmaier G, Flyvbjerg A, Lindner T, Dahne M, Roenne I, Haas N (2001) Homologous growth hormone accelerates healing of segmental bone defects. Bone 29: 368–373.

    Article  CAS  PubMed  Google Scholar 

  16. Raschke MJ, Bail H, Windhagen HJ, Kolbeck SF, Weiler A, Raun K, Kappelgard A, Skiaerbaek C, Haas NP (1999) Recombinant growth hormone accelerates bone regenerate consolidation in distraction osteogenesis. Bone 24: 81–88.

    Article  CAS  PubMed  Google Scholar 

  17. Sanderson PJ (1989) Preventing infection in orthopaedic implants. J Antimicrob Chemother 24: 277–280.

    CAS  PubMed  Google Scholar 

  18. Schmidmaier G, Wildemann B, Bail H, Lucke M, Fuchs T, Stemberger A, Flyvbjerg A, Haas NP, Raschke M (2001) Local application of growth factors (insulin-like growth factor-1 and transforming growth factor-β1) from a biodegradable poly(D,L-lactide) coating of osteosynthetic implants accelerates fracture healing in rats. Bone 28: 341–350.

    Article  CAS  PubMed  Google Scholar 

  19. Schmidmaier G, Wildemann B, Stemberger A, Haas NP, Raschke M (2001) Biodegradable poly(D,L-lactide) coating of implants for continuous release of growth factors. J Biomed Mater Res, Applied Biomat 58: 449–455.

    CAS  Google Scholar 

  20. Southorn PA, Plevak DJ, Wright AJ, Wilson WR (1986) Adverse effects of vancomycin administered in the perioperative period. Mayo Clin Proc 61: 721–724.

    CAS  PubMed  Google Scholar 

  21. Sumner DR, Turner TM, Purchio AF, Gombotz WR, Urban RM, Galante JO (1995) Enhancement of bone ingrowth by transforming growth factor-beta. J Bone Joint Surg Am 77: 1135–1147.

    CAS  PubMed  Google Scholar 

  22. Suter F, Avai A, Fusco U, Gerundini M, Caprioli S, Maggiolo F (1994) Teicoplanin versus cefamandole in the prevention of infection in total hip replacement. Eur J Clin Microbiol Infect Dis 13: 793–796.

    Article  CAS  PubMed  Google Scholar 

  23. Taylor GJ, Bannister GC, Calder S (1990) Perioperative wound infection in elective orthopaedic surgery [published erratum appears in J Hosp Infect 1991; 17(2): 155]. J Hosp Infect 16: 241–247.

    Article  CAS  PubMed  Google Scholar 

  24. Wall R, Klenerman L, McCullough C, Fyfe I (1988) A comparison of teicoplanin and cefuroxime as prophylaxis for orthopaedic implant surgery: a preliminary report. J Antimicrob Chemother 21(Suppl A): 141–146.

    PubMed  Google Scholar 

  25. Wood MJ (1996) The comparative efficacy and safety of teicoplanin and vancomycin [see comments] [published erratum appears in J Antimicrob Chemother 1996; 38(5): 919 and 1997; 40(1): 147]. J Antimicrob Chemother 37: 209–222.

    CAS  PubMed  Google Scholar 

  26. Yasko AW, Lane JM, Fellinger EJ, Rosen V, Wozney JM, Wang EA (1992) The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats. J Bone Joint Surg Am 74: 659–670.

    CAS  PubMed  Google Scholar 

  27. Zheng MH, Wood DJ, Papadimitriou JM (1992) What’s new in the role of cytokines on osteoblast proliferation and differentiation? Pathol Res Pract 188: 1104–1121.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Klinik und Poliklinik für Unfall-, Hand- und Wiederherstellungschirurgie, Westfälische Wilhelms-Universität Münster, Waldeyerstraße 1, 48149, Münster, Germany

    M. J. Raschke, T. Fuchs & R. Stange

  2. Zentrum für Muskolo Skeletale Chirurgie der Charité Berlin (CMSC) Klinik für Unfall- und Wiederherstellungschirurgie, Champus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany

    M. Lucke, B. Wildemann & G. Schmidmaier

  3. Zentrum für Muskolo Skeletale Chirurgie der Charité Berlin (CMSC) Klinik für Orthopädie, Champus Charité Mitte, Schumannstraße 20/21, 10117, Berlin, Germany

    F. Kandziora

Authors
  1. M. J. Raschke
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. Fuchs
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Stange
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. Lucke
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. F. Kandziora
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. B. Wildemann
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. G. Schmidmaier
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, Republic of China

    Kwok-Sui Leung

  2. Centre de Traumatologie et d’Orthopédie, 10 Avenue A. Baumann, 67400, Illkirch-Graffenstaden, France

    Gilbert Taglang

  3. Klinik und Poliklinik für Unfallchirurgie, Universitätsklinikum Gießen, Rudolf-Buchheim-Str. 7, 35385, Gießen, Germany

    Reinhard Schnettler  & Volker Alt  & 

  4. Department of Surgery, Academisch Ziekenhuis, De Boelelaan 1117, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands

    H. J. T. M. Haarman

  5. Rewentlowstr. 48, 22605, Hamburg, Germany

    Hartmut Seidel

  6. AIOD, Rue du Parc, 16, 67205, Oberhausbergen, France

    Ivan Kempf

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer Berlin · Heidelberg

About this chapter

Cite this chapter

Raschke, M.J. et al. (2006). Active Coating of Implants used in Orthopedic Surgery. In: Leung, KS., et al. Practice of Intramedullary Locked Nails. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-32345-7_29

Download citation

  • DOI: https://doi.org/10.1007/3-540-32345-7_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-25349-5

  • Online ISBN: 978-3-540-32345-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation